Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dorothee Terhardt"'
Autor:
Soniya Savant, Silvia La Porta, Annika Budnik, Katrin Busch, Junhao Hu, Nathalie Tisch, Claudia Korn, Aida Freire Valls, Andrew V. Benest, Dorothee Terhardt, Xianghu Qu, Ralf H. Adams, H. Scott Baldwin, Carmen Ruiz de Almodóvar, Hans-Reimer Rodewald, Hellmut G. Augustin
Publikováno v:
Cell Reports, Vol 12, Iss 11, Pp 1761-1773 (2015)
Tie1 is a mechanistically poorly characterized endothelial cell (EC)-specific orphan receptor. Yet, Tie1 deletion is embryonic lethal and Tie1 has been implicated in critical vascular pathologies, including atherosclerosis and tumor angiogenesis. Her
Externí odkaz:
https://doaj.org/article/8a8bd19bf7e943c8ba49e7bf3501a59e
Autor:
Moritz Felcht, Hellmut G. Augustin, Kairbaan M. Hodivala-Dilke, Sergij Goerdt, Markus Thomas, Jochen Utikal, Cyrill Géraud, Dorothee Terhardt, Louise E. Reynolds, Nicolas Gengenbacher, Anja Gampp, Benjamin Schieb, Carolin Mogler, Corinne Hübers, Mahak Singhal, Ashik Ahmed Abdul Pari
The angiopoietin (Angpt)–TIE signaling pathway controls vascular maturation and maintains the quiescent phenotype of resting vasculature. The contextual agonistic and antagonistic Tie2 ligand ANGPT2 is believed to be exclusively produced by endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59e3921bd8e86136df6666680597eaf7
https://doi.org/10.1158/0008-5472.c.6511466.v1
https://doi.org/10.1158/0008-5472.c.6511466.v1
Autor:
Moritz Felcht, Hellmut G. Augustin, Kairbaan M. Hodivala-Dilke, Sergij Goerdt, Markus Thomas, Jochen Utikal, Cyrill Géraud, Dorothee Terhardt, Louise E. Reynolds, Nicolas Gengenbacher, Anja Gampp, Benjamin Schieb, Carolin Mogler, Corinne Hübers, Mahak Singhal, Ashik Ahmed Abdul Pari
This file consists of supplementary figures (SF) 1-11 consisting of: SF1: Melanoma cells express ANGPT2 (A-F). SF2: Melanoma cell-expressed Angpt2 does not modulate tumor cell proliferation (A-B). SF3: Tumor cell knockdown of Angpt2 does not impact g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449cc8e11f6161b45bdcc4084ff2d5e3
https://doi.org/10.1158/0008-5472.22423301
https://doi.org/10.1158/0008-5472.22423301
Autor:
Anja Gampp, Moritz Felcht, Louise E. Reynolds, Jochen Utikal, Carolin Mogler, Hellmut G. Augustin, Dorothee Terhardt, Benjamin Schieb, Mahak Singhal, Corinne Hübers, Cyrill Géraud, Kairbaan Hodivala-Dilke, Markus Thomas, Sergij Goerdt, Nicolas Gengenbacher, Ashik Ahmed Abdul Pari
Publikováno v:
Cancer Research
Cancer Res
Cancer Res
The angiopoietin (Angpt)–TIE signaling pathway controls vascular maturation and maintains the quiescent phenotype of resting vasculature. The contextual agonistic and antagonistic Tie2 ligand ANGPT2 is believed to be exclusively produced by endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838fdbc994b61bcb65b2198d82aeea77
https://doi.org/10.1158/0008-5472.can-19-2660
https://doi.org/10.1158/0008-5472.can-19-2660
Autor:
Arefeh Rouhi, Ingrid Lohmann, Dorothee Terhardt, Bahtiyar Kurtulmus, Gislene Pereira, Stefan Fröhling, Laura Schwarzmüller, Stefan Koch, Hanno Glimm, Christof Niehrs, Claudia Scholl, Karsten Richter, Raffaela K. Bung, Leila R. Martins
Publikováno v:
Developmental biology. 433(1)
Spermiogenesis is the final phase during sperm cell development in which round spermatids undergo dramatic morphological changes to generate spermatozoa. Here we report that the serine/threonine kinase Stk33 is essential for the differentiation of ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7ec0cfc935d0bf858bac543f641966
https://pubmed.ncbi.nlm.nih.gov/29155043
https://pubmed.ncbi.nlm.nih.gov/29155043
Autor:
Yvonne Kienast, Elias K. Loos, Kshitij Srivastava, Christian Klein, Philipp Seidel, Sila Appak, Thomas Wieland, Moritz Felcht, Simone Kutschera, Emmanouil Chavakis, Dorothee Terhardt, Eva Besemfelder, Alexander Schering, Hellmut G. Augustin, Robert Luck, Akiyoshi Uemura, Christiane Vettel, Junhao Hu, Susanne Bartels, Arne Bartol, Sergij Goerdt, Markus Thomas
Publikováno v:
Journal of Clinical Investigation. 122:1991-2005
Angiopoietin-2 (ANG-2) is a key regulator of angiogenesis that exerts context-dependent effects on ECs. ANG-2 binds the endothelial-specific receptor tyrosine kinase 2 (TIE2) and acts as a negative regulator of ANG-1/TIE2 signaling during angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b9bea6d81d05b73f2e26416fd70429
https://doi.org/10.1172/jci58832
https://doi.org/10.1172/jci58832