Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Dorothee Schwinge"'
Autor:
Timur Liwinski, Matthias K. Auer, Johanna Schröder, Ina Pieknik, Christian Casar, Dorothee Schwinge, Lara Henze, Günter K. Stalla, Undine E. Lang, Alina von Klitzing, Peer Briken, Thomas Hildebrandt, Jeanne C. Desbuleux, Sarah V. Biedermann, Paul-Martin Holterhus, Corinna Bang, Christoph Schramm, Johannes Fuss
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Limited data exists regarding gender-specific microbial alterations during gender-affirming hormonal therapy (GAHT) in transgender individuals. This study aimed to investigate the nuanced impact of sex steroids on gut microbiota t
Externí odkaz:
https://doaj.org/article/7f249955ebc14b3d8b189060516f30f8
Autor:
Daria Krzikalla, Alena Laschtowitz, Lisa Leypoldt, Cornelia Gottwick, Pia Averhoff, Sören Weidemann, Ansgar W. Lohse, Samuel Huber, Christoph Schramm, Dorothee Schwinge, Johannes Herkel, Antonella Carambia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 79-91 (2024)
Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also can be detrimental by preventing immune sur
Externí odkaz:
https://doaj.org/article/5bdb57d96fae45dab3880fcdea472873
Autor:
Julian Stürznickel, Friederike Behler-Janbeck, Anke Baranowsky, Tobias Schmidt, Dorothee Schwinge, Clara John, Ansgar W. Lohse, Christoph Schramm, Joerg Heeren, Thorsten Schinke, Michael Amling
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Primary sclerosing cholangitis (PSC) is an idiopathic cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of intra- and extrahepatic bile ducts. Osteoporosis is a frequent comorbidity in PSC, and we could
Externí odkaz:
https://doaj.org/article/d7c763f5573d4cf5bf7c82ef35f5acfe
Autor:
Thomas Theo Brehm, Felix Ullrich, Michelle Thompson, Julia Küchen, Dorothee Schwinge, Anthea Spier, Samuel Huber, Johannes K. Knobloch, Martin Aepfelbacher, Marylyn M. Addo, Ansgar W. Lohse, Marc Lütgehetmann, Julian Schulze zur Wiesch
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1086 (2022)
Background: The immunogenicity of different COVID-19 vaccine regimens and combinations in naïve and convalescent individuals has not been formally tested in controlled studies, and real-life observational studies are scarce. Methods: We assessed the
Externí odkaz:
https://doaj.org/article/72571dcfd8984633938a963ba3901d5b
Autor:
Max Preti, Lena Schlott, David Lübbering, Daria Krzikalla, Anna-Lena Müller, Fenja A. Schuran, Tobias Poch, Miriam Schakat, Sören Weidemann, Ansgar W. Lohse, Christina Weiler-Normann, Marcial Sebode, Dorothee Schwinge, Christoph Schramm, Antonella Carambia, Johannes Herkel
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic control and attack the liver. To elucidate how tolerance to self-antigens is lost during AIH pa
Externí odkaz:
https://doaj.org/article/562c142691284b8baadaf1974c991cea
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immune system responds differently in women and in men. Generally speaking, adult females show stronger innate and adaptive immune responses than males. This results in lower risk of developing most of the infectious diseases and a better ability
Externí odkaz:
https://doaj.org/article/8fb79004c91c429e8f845c1f1777a876
Autor:
Ioannis Evangelakos, Dorothee Schwinge, Anna Worthmann, Clara John, Niklas Roeder, Paul Pertzborn, Janina Behrens, Christoph Schramm, Ludger Scheja, Joerg Heeren
Publikováno v:
Cells, Vol 10, Iss 10, p 2656 (2021)
Ambient temperature is an important determinant of both the alternative bile acid synthesis pathway controlled by oxysterol 7-α hydroxylase (CYP7B1) and the progression of metabolic-associated fatty liver disease (MAFLD). Here, we investigated wheth
Externí odkaz:
https://doaj.org/article/a8d8892c9cc14b3a8b42f45e22b5b9d1
Autor:
Jasmin Heidepriem, Christine Dahlke, Robin Kobbe, René Santer, Till Koch, Anahita Fathi, Bruna M. S. Seco, My L. Ly, Stefan Schmiedel, Dorothee Schwinge, Sonia Serna, Katrin Sellrie, Niels-Christian Reichardt, Peter H. Seeberger, Marylyn M. Addo, Felix F. Loeffler, on behalf of the ID-UKE COVID-19 Study Group
Publikováno v:
Pathogens, Vol 10, Iss 4, p 438 (2021)
The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). A better understanding of its immunogenicity can be important for the development of improved diagnostics, therapeutics, and vaccines. Here,
Externí odkaz:
https://doaj.org/article/dd6757be35ea4e93b0c120867419fac9
Autor:
Tanja Trautmann, Jan-Hendrik Kozik, Antonella Carambia, Kirsten Richter, Timo Lischke, Dorothee Schwinge, Hans-Willi Mittrücker, Ansgar W Lohse, Annette Oxenius, Christiane Wiegard, Johannes Herkel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86348 (2014)
Cytotoxic CD8+ T cells are essential for the control of viral liver infections, such as those caused by HBV or HCV. It is not entirely clear whether CD4+ T-cell help is necessary for establishing anti-viral CD8+ T cell responses that successfully con
Externí odkaz:
https://doaj.org/article/df0c44a94aae4620b2011e6b311ee2af
Autor:
Jonas Bahn, Lilly K. Kunzmann, Jenny Krause, Christian Casar, Silja Steinmann, Marcial Sebode, Samuel Huber, Ansgar W. Lohse, Andre Franke, Nicola Gagliani, Dorothee Schwinge, Christoph Schramm, Tobias Poch
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35c20283b418712325382865cc95784
https://doi.org/10.1055/s-0042-1760065
https://doi.org/10.1055/s-0042-1760065