Výsledky vyhledávání - "Dorothee Langer"

Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic–pharmacodynamic model in gastrointestinal cancer patients

Autor: Usman Arshad, Alexander Jetter, Sami Ullah, Su-arpa Ploylearmsaeng, Semih A. Güner, Uwe Fuhr, Edgar Schömig, Ulrich Jaehde, Mats O. Karlsson, Max Taubert, Sabine Kunze, Oxana Doroshyenko, Dorothee Langer, Roman Skripnichenko

Publikováno v: Cancer Chemotherapy and Pharmacology

Purpose To describe 5-fluorouracil (5FU) pharmacokinetics, myelotoxicity and respective covariates using a simultaneous nonlinear mixed effect modelling approach. Methods Thirty patients with gastrointestinal cancer received 5FU 650 or 1000 mg/m2/day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1255c0837ea1a706d2fca2dd54a4b7
http://europepmc.org/articles/PMC7125253

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