Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Dorothee Buet"'
1
p210BCR-ABL inhibits SDF-1 Chemotactic Response via Alteration of CXCR4 Signaling and Down-regulation of CXCR4 Expression
Autor: Fawzia Louache, Dorothee Buet, Ali G. Turhan, Adlen Foudi, Peggy Jarrier, Magali Berthebaud, Jean-Francois Geay, Yanyan Zhang, William Vainchenker
Publikováno v: Cancer Research. 65:2676-2683
It has been shown that p210BCR-ABL significantly impairs CXCR4 signaling. We report here that the migratory response to SDF-1 was profoundly altered in blast crisis, whereas chronic-phase CD34+ cells migrated normally to this chemokine. This migrator
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d033af01e2a34e04c1e7575d00ca5bba
https://doi.org/10.1158/0008-5472.can-04-2152
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2
p210(BCR-ABL) reprograms transformed and normal human megakaryocytic progenitor cells into erythroid cells and suppresses FLI-1 transcription
Autor: P. Jarrier, Vladimir Lazar, Ali G. Turhan, Jean-Francois Geay, Hana Raslova, F. Morle, Dorothee Buet, William Vainchenker, Fawzia Louache
Publikováno v: Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2007, 21 (5), pp.917-25. ⟨10.1038/sj.leu.2404600⟩
International audience; The BCR-ABL oncoprotein exhibits deregulated protein tyrosine kinase activity and is implicated in the pathogenesis of Philadelphia chromosome (Ph)-positive human leukemias. Here, we report that ectopic expression of p210(BCR-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefec3cb931e4955b455faaf55534151
https://hal.archives-ouvertes.fr/hal-00176495
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3
Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells
Autor: Aadlen Foudi, Dorothee Buet, Fawzia Louache, Peggy Jarrier, William Vainchenker, Abdelale Jalil, Magali Berthebaud, Yanyan Zhang, Jean-Francois Geay
Publikováno v: Stem cells (Dayton, Ohio). 22(6)
CXCR4, the stromal cell-derived factor-1 receptor, plays an important role in the migration of hematopoietic progenitor/stem cells. The surface and cytoplasmic expression of CXCR4 on human hematopoietic CD34(+) cells was investigated. We show that it
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1582217e7fc0c9f048e324bdc634a3
https://pubmed.ncbi.nlm.nih.gov/15536192
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4
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation
Autor: Evelyne Ségal-Bendirdjian, Michel Lanotte, Frédéric Pendino, François Delhommeau, Maria Flexor, Dorothee Buet
Human telomerase, a cellular reverse transcriptase (hTERT), is a nuclear ribonucleoprotein enzyme complex that catalyzes the synthesis and extension of telomeric DNA. This enzyme is specifically activated in most malignant tumors but is usually inact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ed719e8936f24f7ee5e0237a447061
https://europepmc.org/articles/PMC34517/
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5
p210BCR-ABL by down Regulating FLI-1 Reprograms Megakaryocytic Progenitors to the Erythroid Lineage
Autor: Peggy Jarrier, Hana Raslova, Fawzia Louache, Dorothee Buet, Jean-François Geay, Ali G. Turhan, Gaëtan Juban, François Morlé, William Vainchenker
Publikováno v: ResearcherID
Blood cells derive from a common multipotent stem cell that undergoes successive commitment steps with progressive restriction in differentiation ability. A close developmental relationship exists between the erythroid and megakaryocytic (MK) lineage
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a233c0b4aa3b811bd221e2be52fb6218
https://doi.org/10.1182/blood.v106.11.2275.2275
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6
Implication of HIF-1α but Not HIF-2α in the Hypoxic Response of Human Hematopoietic Progenitors
Autor: Fawzia Louache, Peggy Jarrier, William Vainchenker, Dorothee Buet, Adlen Foudi, Magali Berthebaud, Yanyan Zhang
Publikováno v: Blood. 104:4154-4154
Maturing hematopoietic cells are exposed to hypoxia as they develop and migrate within the bone marrow microenvironment. Previous studies using non hematopoietic cell lines and monocytes showed that CXCR4 is strongly induced by hypoxia but little is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7d10b4ea5bf6e654d439967f0b1efdf
https://doi.org/10.1182/blood.v104.11.4154.4154
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9
Akademický článek
Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase.
Autor: Olivier Kosmider, Dorothée Buet, Isabelle Gallais, Nicole Denis, Françoise Moreau-Gachelin
Publikováno v: PLoS ONE, Vol 4, Iss 5, p e5721 (2009)
Overexpression of the transcription factor Spi-1/PU.1 by transgenesis in mice induces a maturation arrest at the proerythroblastic stage of differentiation. We have previously isolated a panel of spi-1 transgenic erythroleukemic cell lines that proli
Externí odkaz: https://doaj.org/article/54db0c28ad72421db2a0b3cc1eb8f84f
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