Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Dorothea Sesardic"'
Autor:
Stéphanie Simon, Uwe Fiebig, Yvonne Liu, Rob Tierney, Julie Dano, Sylvia Worbs, Tanja Endermann, Marie-Claire Nevers, Hervé Volland, Dorothea Sesardic, Martin B. Dorner
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5011-5034 (2015)
Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G), of which serotypes A, B, E, and F cause the disease in humans. BoNTs are classified as “
Externí odkaz:
https://doaj.org/article/d003a6c695274957bdc7afab0b6c2114
Autor:
Aleksander Rust, Ciara Doran, Rosalyn Hart, Thomas Binz, Paul Stickings, Dorothea Sesardic, Andrew A. Peden, Bazbek Davletov
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles. Their exquisite neuronal specificity is conferred by a multistep process of bi
Externí odkaz:
https://doaj.org/article/a5d1ff3943c640b299a8d604ee755862
Autor:
Sebastian Miethe, Christelle Mazuet, Yvonne Liu, Robert Tierney, Christine Rasetti-Escargueil, Arnaud Avril, André Frenzel, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Dorothea Sesardic, Michael Hust, Michel Robert Popoff
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161446 (2016)
Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of th
Externí odkaz:
https://doaj.org/article/3dfe8169d86e47538b9d3a846c6718a2
Autor:
Sebastian Miethe, Christine Rasetti-Escargueil, Arnaud Avril, Yvonne Liu, Siham Chahboun, Hannu Korkeala, Christelle Mazuet, Michel-Robert Popoff, Thibaut Pelat, Philippe Thullier, Dorothea Sesardic, Michael Hust
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139905 (2015)
Botulinum neurotoxins (BoNTs) are considered to be the most toxic substances known on earth and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food-poisoning or coloni
Externí odkaz:
https://doaj.org/article/f9e47233b8c54c6186db6486b060e678
Autor:
Christine Rasetti-Escargueil, Arnaud Avril, Sebastian Miethe, Christelle Mazuet, Yagmur Derman, Katja Selby, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Hannu Korkeala, Dorothea Sesardic, Michael Hust, Michel R. Popoff
Publikováno v:
Toxins, Vol 9, Iss 10, p 309 (2017)
The goal of the AntiBotABE Program was the development of recombinant antibodies that neutralize botulinum neurotoxins (BoNT) A, B and E. These serotypes are lethal and responsible for most human botulinum cases. To improve therapeutic efficacy, the
Externí odkaz:
https://doaj.org/article/424bc2d0ad4943e583c273befd72cfe0
Publikováno v:
Toxins, Vol 9, Iss 7, p 230 (2017)
Botulinum toxins (BoNTs), of which there are seven serotypes, are among the most potent neurotoxins, with serotypes A, B and E causing human botulism. Antitoxins form the first line of treatment for botulism, and functional, highly sensitive in vitro
Externí odkaz:
https://doaj.org/article/5641e63ee04547e69a11c9084c302af6
Autor:
Michael W. Peck, Theresa J. Smith, Fabrizio Anniballi, John W. Austin, Luca Bano, Marite Bradshaw, Paula Cuervo, Luisa W. Cheng, Yagmur Derman, Brigitte G. Dorner, Audrey Fisher, Karen K. Hill, Suzanne R. Kalb, Hannu Korkeala, Miia Lindström, Florigio Lista, Carolina Lúquez, Christelle Mazuet, Marco Pirazzini, Michel R. Popoff, Ornella Rossetto, Andreas Rummel, Dorothea Sesardic, Bal Ram Singh, Sandra C. Stringer
Publikováno v:
Toxins, Vol 9, Iss 1, p 38 (2017)
Botulinum neurotoxins are diverse proteins. They are currently represented by at least seven serotypes and more than 40 subtypes. New clostridial strains that produce novel neurotoxin variants are being identified with increasing frequency, which pre
Externí odkaz:
https://doaj.org/article/98919fbc4fc146f884f461918e1dbd37
Autor:
Yağmur Derman, Katja Selby, Sebastian Miethe, André Frenzel, Yvonne Liu, Christine Rasetti-Escargueil, Arnaud Avril, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Philippe Thullier, Dorothea Sesardic, Miia Lindström, Michael Hust, Hannu Korkeala
Publikováno v:
Toxins, Vol 8, Iss 9, p 257 (2016)
Botulinum neurotoxins (BoNTs) cause botulism and are the deadliest naturally-occurring substances known to humans. BoNTs have been classified as one of the category A agents by the Centers for Disease Control and Prevention, indicating their potentia
Externí odkaz:
https://doaj.org/article/e6ae5f8316ed4cf0bfb1033ad2975a5e
Publikováno v:
Journal of Immunological Methods. 451:90-99
Botulinum toxin type A is a causative agent of human botulism. Due to high toxicity and ease of production it is classified by the Centres for Disease Control and Prevention as a category A bioterrorism agent. The same serotype, BoNT/A, is also the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99306f90566fac9944cf5c19cc1d159b
https://doi.org/10.1016/j.jim.2017.09.007
https://doi.org/10.1016/j.jim.2017.09.007
Autor:
Esther Veronika Wenzel, Margarita Bosnak, Robert Tierney, Maren Schubert, Jeffrey Brown, Stefan Dübel, Androulla Efstratiou, Dorothea Sesardic, Paul Stickings, Michael Hust
Publikováno v:
Scientific Reports
Scientific reports, 10, 571 (2020). https://doi.org/10.1038/s41598-019-57103-5--Sci Rep--http://www.bibliothek.uni-regensburg.de/ezeit/?2615211--https://www.nature.com/srep/--2045-2322--2045-2322
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific reports, 10, 571 (2020). https://doi.org/10.1038/s41598-019-57103-5--Sci Rep--http://www.bibliothek.uni-regensburg.de/ezeit/?2615211--https://www.nature.com/srep/--2045-2322--2045-2322
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Diphtheria is an infectious disease caused by Corynebacterium diphtheriae. The bacterium primarily infects the throat and upper airways and the produced diphtheria toxin (DT), which binds to the elongation factor 2 and blocks protein synthesis, can s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aee7677103f85e4fc5e3a1f13c982d6a
https://pubmed.ncbi.nlm.nih.gov/31953428
https://pubmed.ncbi.nlm.nih.gov/31953428