Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Dorothea Rutishauser"'
Autor:
Farshid Jalalvand, Yu-Ching Su, Guillaume Manat, Alexey Chernobrovkin, Mahendar Kadari, Sandra Jonsson, Martina Janousková, Dorothea Rutishauser, Szabolcs Semsey, Anders Løbner-Olesen, Linda Sandblad, Klas Flärdh, Dominique Mengin-Lecreulx, Roman A. Zubarev, Kristian Riesbeck
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The human pathogen Haemophilus influenzae causes respiratory tract infections and is commonly associated with prolonged carriage in patients with chronic obstructive pulmonary disease. Production of outer membrane vesicles (OMVs) is a ubiquitous phen
Externí odkaz:
https://doaj.org/article/70ab3a33c8d84209897232a1f10d2f9e
Autor:
Konstantina Charmpi, Tiannan Guo, Qing Zhong, Ulrich Wagner, Rui Sun, Nora C. Toussaint, Christine E. Fritz, Chunhui Yuan, Hao Chen, Niels J. Rupp, Ailsa Christiansen, Dorothea Rutishauser, Jan H. Rüschoff, Christian Fankhauser, Karim Saba, Cedric Poyet, Thomas Hermanns, Kathrin Oehl, Ariane L. Moore, Christian Beisel, Laurence Calzone, Loredana Martignetti, Qiushi Zhang, Yi Zhu, María Rodríguez Martínez, Matteo Manica, Michael C. Haffner, Ruedi Aebersold, Peter J. Wild, Andreas Beyer
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-31 (2020)
Abstract Background Tumor-specific genomic aberrations are routinely determined by high-throughput genomic measurements. It remains unclear how complex genome alterations affect molecular networks through changing protein levels and consequently bioc
Externí odkaz:
https://doaj.org/article/707dce3d6d5841db93fe381dce66b0c0
Autor:
Yi Zhu, Tobias Weiss, Qiushi Zhang, Rui Sun, Bo Wang, Xiao Yi, Zhicheng Wu, Huanhuan Gao, Xue Cai, Guan Ruan, Tiansheng Zhu, Chao Xu, Sai Lou, Xiaoyan Yu, Ludovic Gillet, Peter Blattmann, Karim Saba, Christian D. Fankhauser, Michael B. Schmid, Dorothea Rutishauser, Jelena Ljubicic, Ailsa Christiansen, Christine Fritz, Niels J. Rupp, Cedric Poyet, Elisabeth Rushing, Michael Weller, Patrick Roth, Eugenia Haralambieva, Silvia Hofer, Chen Chen, Wolfram Jochum, Xiaofei Gao, Xiaodong Teng, Lirong Chen, Qing Zhong, Peter J. Wild, Ruedi Aebersold, Tiannan Guo
Publikováno v:
Molecular Oncology, Vol 13, Iss 11, Pp 2305-2328 (2019)
Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable resource for clinical and biomarker research. Here, we developed a pressure cycling technology (PCT)‐SWATH mass spectrometry workflow to analyze FFPE tissue
Externí odkaz:
https://doaj.org/article/d5ac540ae607488999e040459d781060
Autor:
Wenguang Shao, Tiannan Guo, Nora C. Toussaint, Peng Xue, Ulrich Wagner, Li Li, Konstantina Charmpi, Yi Zhu, Jianmin Wu, Marija Buljan, Rui Sun, Dorothea Rutishauser, Thomas Hermanns, Christian Daniel Fankhauser, Cedric Poyet, Jelena Ljubicic, Niels Rupp, Jan H. Rüschoff, Qing Zhong, Andreas Beyer, Jiafu Ji, Ben C. Collins, Yansheng Liu, Gunnar Rätsch, Peter J. Wild, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Protein degradation in clinical samples is largely unexplored. Here, the authors analyze the transcriptome and proteome of clinical tissue samples and develop an algorithm to assess protein degradation, showing that protein degradation is negligible
Externí odkaz:
https://doaj.org/article/5e2fad9e30374816bb16c6dcb2619e1f
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Clear cell renal cell carcinoma (ccRCC) displays a highly varying clinical progression, from slow growing localized tumors to very aggressive metastatic disease (mRCC). Almost a third of all patients with ccRCC show metastatic dissemination at presen
Externí odkaz:
https://doaj.org/article/a4961c0032f8499f8934ff2a8f4246ce
Autor:
Susanna L. Lundström, Aase H. Hensvold, Dorothea Rutishauser, Lars Klareskog, A. Jimmy Ytterberg, Roman A. Zubarev, Anca I. Catrina
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in RA and influenced by
Externí odkaz:
https://doaj.org/article/e2803ed95ee74d43a91fcfeddcadf46e
Autor:
Ronald F. S. Lee, Alexey Chernobrovkin, Dorothea Rutishauser, Claire S. Allardyce, David Hacker, Kai Johnsson, Roman A. Zubarev, Paul J. Dyson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The emerging technique termed functional identification of target by expression proteomics (FITExP) has been shown to identify the key protein targets of anti-cancer drugs. Here, we use this approach to elucidate the proteins involved in the
Externí odkaz:
https://doaj.org/article/4de57fb3c86d42eab3c5f8158d0517a9
Publikováno v:
Cells, Vol 9, Iss 9, p 2126 (2020)
Cells recovering from the G2/M DNA damage checkpoint rely more on Aurora A-PLK1 signaling than cells progressing through an unperturbed G2 phase, but the reason for this discrepancy is not known. Here, we devised a method based on a FRET reporter for
Externí odkaz:
https://doaj.org/article/32266436397145bc8973ff44ee1f8bbd
Autor:
Katja Baerenfaller, Catherine Massonnet, Sean Walsh, Sacha Baginsky, Peter Bühlmann, Lars Hennig, Matthias Hirsch‐Hoffmann, Katharine A Howell, Sabine Kahlau, Amandine Radziejwoski, Doris Russenberger, Dorothea Rutishauser, Ian Small, Daniel Stekhoven, Ronan Sulpice, Julia Svozil, Nathalie Wuyts, Mark Stitt, Pierre Hilson, Christine Granier, Wilhelm Gruissem
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-18 (2012)
Abstract Leaves have a central role in plant energy capture and carbon conversion and therefore must continuously adapt their development to prevailing environmental conditions. To reveal the dynamic systems behaviour of leaf development, we profiled
Externí odkaz:
https://doaj.org/article/0aca5a1947684033b5e7c7cc2a3c745a
Autor:
Shiva Kalantari, Dorothea Rutishauser, Shiva Samavat, Mohsen Nafar, Leyla Mahmudieh, Mostafa Rezaei-Tavirani, Roman A Zubarev
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80830 (2013)
IgA nephropathy is the most common cause of primary glomerulonephritis. There are different pathologic biopsy-based scoring systems in use, but there is no consensus among nephrologists yet regarding the best classification method. Our aim was to tes
Externí odkaz:
https://doaj.org/article/d2d609a647df431dbf2d28758472e356