Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dorothea I. Axel"'
Autor:
Ioakim Spyridopoulos, Karl R. Karsch, Kerida Shook, Dorothea I. Axel, R. Viebahn, Petra Mayer
Publikováno v:
Cardiovascular Research. 50:97-107
Background: Ceramide is an important messenger of TNF- and lipid-induced apoptosis. We previously demonstrated the adverse effect of TNF in the process of reendothelialization as well as the dependence of its effect on cell-cycle regulation. The curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e223e7eb51f67dcfb64c347082d30e9a
https://doi.org/10.1016/s0008-6363(01)00196-1
https://doi.org/10.1016/s0008-6363(01)00196-1
Autor:
Jörg Wischhusen, Dorothea I. Axel, Björn Rabenstein, Kai-Uwe Fröhlich, Karl R. Karsch, Petra Mayer, Ioakim Spyridopoulos
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 21:439-444
Abstract —Controversy exists about the net effect of alcohol on atherogenesis. A protective effect is assumed, especially from the tannins and phenolic compounds in red wine, owing to their inhibition of low density lipoprotein (LDL) oxidation. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a7988f45ea72c9fdc0234b689ccc1b
https://doi.org/10.1161/01.atv.21.3.439
https://doi.org/10.1161/01.atv.21.3.439
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 21:47-54
Abstract —Cartilage oligomeric matrix protein (COMP/thrombospondin [TSP]-5) belongs to the thrombospondin gene family and is an extracellular glycoprotein found predominantly in cartilage and tendon. To date, there is limited evidence of COMP/TSP-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6908927183d274d9341e232423632a
https://doi.org/10.1161/01.atv.21.1.47
https://doi.org/10.1161/01.atv.21.1.47
Publikováno v:
Journal of Cardiovascular Pharmacology. 35:619-629
Summary: Statins competitively inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity reducing mevalonate synthesis. In this study, antiproliferative and antimigratory effects of the new compound cerivastatin were analyzed and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1c7c3d036bf8007357fe2cd70c146e
https://doi.org/10.1097/00005344-200004000-00016
https://doi.org/10.1097/00005344-200004000-00016
Autor:
Jens Bangsbo, Karl R. Karsch, David J. Grieve, Heike Runge, Daniel A. Beard, Henning Langberg, Ioakim Spyridopoulos, Friederike Neumann, Rudolf Karch, Ulrik Frandsen, Thérèse Keravis, Martin Neumann, Michael Avella, James M. Ritter, Claire Lugnier, Kathleen M. Botham, Jonathan Elliott, Narcisse Komas, M Dawes, Wolfgang Schreiner, Ylva Hellsten, Reimer Riessen, R. Viebahn, Bengt Saltin, James B. Bassingthwaighte, Dorothea I. Axel
Publikováno v:
Journal of Vascular Research. 37:305-339
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82189e3a14374ad87c342a830f9466b
https://doi.org/10.1159/000025745
https://doi.org/10.1159/000025745
Publikováno v:
Basic Research in Cardiology. 94:322-332
Clinical studies have shown that treatment with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors can stabilize atherosclerotic plaques and slow their progression. One determinant of plaque stability and size is the composition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44af4412114369c9c0c9e2a8b7e7fe98
https://doi.org/10.1007/s003950050158
https://doi.org/10.1007/s003950050158
Autor:
Karl R. Karsch, Dorothea I. Axel, Reimer Riessen, Heike Runge, Anastasios Athanasiadis, Gerhard Köveker
Publikováno v:
Journal of Molecular and Cellular Cardiology. 29:2967-2978
By releasing growth factors, vascular cells can modulate proliferation and migration of neighboring cells in the arterial wall. Previous histological studies in transfilter cocultures, a culture model aimed to simulate vessel wall architecture, indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af09fbdd741478707ea65c6f0297f5c
https://doi.org/10.1006/jmcc.1997.0541
https://doi.org/10.1006/jmcc.1997.0541
Autor:
Christoph Göggelmann, Doris H. Wild, Martin Oberhoff, Axel Küttner, Gerhard Köveker, Bernhard R. Brehm, Karl R. Karsch, W. Kunert, Reimer Riessen, Christian Herdeg, Dorothea I. Axel
Publikováno v:
Circulation. 96:636-645
Background The antineoplastic compound paclitaxel (Taxol) causes an increased assembly of extraordinarily stable microtubules. The present study was designed to characterize the effects of paclitaxel on proliferation and migration of human arterial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee48572d2bb205b53dd75529202bae9d
https://doi.org/10.1161/01.cir.96.2.636
https://doi.org/10.1161/01.cir.96.2.636
Publikováno v:
Coronary Artery Disease. 4:283-292
BACKGROUND Transfilter culture systems with enzymatically isolated human vascular cells were established to imitate the morphologic situation of the inner parts of a vessel wall. METHODS In transfilter cultures, only smooth muscle cells were seeded o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b286d8cbf336f895c23cb2e7f75f7c92
https://doi.org/10.1097/00019501-199303000-00009
https://doi.org/10.1097/00019501-199303000-00009
Autor:
Ioakim Spyridopoulos, R. Viebahn, Anatol Frigge, Heike Runge, Jasmin Dittmann, Karl R. Karsch, Reimer Riessen, Dorothea I. Axel
Publikováno v:
Cardiovascular research. 49(4)
Objective: The vitamin-A derivative all- trans retinoic acid (atRA) is a potent regulator of cell growth, differentiation, and matrix formation of various cell types and plays an important role in embryogenesis. However, sparse data are available abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bb658f40b8873aa2555db83207ed27
https://pubmed.ncbi.nlm.nih.gov/11230985
https://pubmed.ncbi.nlm.nih.gov/11230985