Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dorothée Selimoglu-Buet"'
Autor:
Awatef Allouch, Laurent Voisin, Yanyan Zhang, Syed Qasim Raza, Yann Lecluse, Julien Calvo, Dorothée Selimoglu-Buet, Stéphane de Botton, Fawzia Louache, Françoise Pflumio, Eric Solary, Jean-Luc Perfettini
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Inducing phagocytic capacities of tumour-associated macrophages to eliminate cancer cells is a promising immunotherapy. Here, the authors show that engineered macrophages overexpressing CDKN1A/p21 reduce leukaemic tumour burden and increase survival
Externí odkaz:
https://doaj.org/article/07cf7b006e8747e9a9f59deeadcf2665
TET2 mutational status affects myelodysplastic syndrome evolution to chronic myelomonocytic leukemia
Autor:
Violaine Tran Quang, Benjamin Podvin, Christophe Desterke, Sihem Tarfi, Quentin Barathon, Bouchra Badaoui, Nicolas Freynet, Vincent Parinet, Mathieu Leclerc, Sébastien Maury, Eric Solary, Dorothée Selimoglu-Buet, Nicolas Duployez, Orianne Wagner-Ballon, Ivan Sloma
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/2f198850b6654505b16fec3cdd502c43
Autor:
Elodie Pronier, Aygun Imanci, Dorothée Selimoglu-Buet, Bouchra Badaoui, Raphael Itzykson, Thierry Roger, Chloé Jego, Audrey Naimo, Maëla Francillette, Marie Breckler, Orianne Wagner-Ballon, Maria E. Figueroa, Marine Aglave, Daniel Gautheret, Françoise Porteu, Olivier A. Bernard, William Vainchenker, François Delhommeau, Eric Solary, Nathalie M. Droin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
To improve our understanding of the pathological role of TET2 mutations, Pronier, Imanci et al. use mice and human cells to show that TET2 downregulation promotes the production of macrophage migration inhibitory factor (MIF). In addition they show t
Externí odkaz:
https://doaj.org/article/4004d3ab528c41bca20e05648bffe239
Autor:
Dorothée Selimoglu-Buet, Julie Rivière, Hussein Ghamlouch, Laura Bencheikh, Catherine Lacout, Margot Morabito, M’boyba Diop, Guillaume Meurice, Marie Breckler, Aurélie Chauveau, Camille Debord, Franck Debeurme, Raphael Itzykson, Nicolas Chapuis, Christophe Willekens, Orianne Wagner-Ballon, Olivier A. Bernard, Nathalie Droin, Eric Solary
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
A decrease in the fraction of non-classical monocytes is a hallmark of chronic myelomonocytic leukaemia. Taking advantage of this abnormal situation, the authors identify a mechanistic link between miR-150 and TET3 as being involved in monocyte subse
Externí odkaz:
https://doaj.org/article/5d55187610e84c0189ca6173abd8c67a
Autor:
Sihem Tarfi, Bouchra Badaoui, Nicolas Freynet, Margot Morabito, Jeffie Lafosse, Andréa Toma, Gabriel Etienne, Jean-Baptiste Micol, Ivan Sloma, Pierre Fenaux, Eric Solary, Dorothée Selimoglu-Buet, Orianne Wagner-Ballon
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/0b18a704ee77422eb811515d5f645bfe
Autor:
Yanyan Zhang, Liang He, Dorothée Selimoglu-Buet, Chloe Jego, Margot Morabito, Christophe Willekens, M'boyba Khadija Diop, Patrick Gonin, Valérie Lapierre, Nathalie Droin, Eric Solary, Fawzia Louache
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 972-979 (2017)
Abstract: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder that typically associates with mutations in epigenetic, splicing, and signaling genes. Genetically modified mouse models only partially recapitulate the dis
Externí odkaz:
https://doaj.org/article/66dbe88188da4911846accf2d6be9a8a
Autor:
Jane Merlevede, Nathalie Droin, Tingting Qin, Kristen Meldi, Kenichi Yoshida, Margot Morabito, Emilie Chautard, Didier Auboeuf, Pierre Fenaux, Thorsten Braun, Raphael Itzykson, Stéphane de Botton, Bruno Quesnel, Thérèse Commes, Eric Jourdan, William Vainchenker, Olivier Bernard, Noemie Pata-Merci, Stéphanie Solier, Velimir Gayevskiy, Marcel E. Dinger, Mark J. Cowley, Dorothée Selimoglu-Buet, Vincent Meyer, François Artiguenave, Jean-François Deleuze, Claude Preudhomme, Michael R. Stratton, Ludmil B. Alexandrov, Eric Padron, Seishi Ogawa, Serge Koscielny, Maria Figueroa, Eric Solary
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Chronic myelomonocytic leukaemia is treated with agents that modify DNA methylation but whether they have direct cytotoxic effects is unclear. Here, the authors show that cells from treated patients show marked methylation changes without altered som
Externí odkaz:
https://doaj.org/article/3d387d13bd0349019c8a2486e3d50c61
Autor:
Dorothée Selimoglu-Buet, Isabelle Gallais, Nicole Denis, Christel Guillouf, Françoise Moreau-Gachelin
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49052 (2012)
Oncogenic mutations leading to persistent kinase activities are implicated in various human malignancies. Thereby, signaling pathway-targeted therapies are powerful customized treatment to eradicate cancer cells. In murine and human leukemia cells ha
Externí odkaz:
https://doaj.org/article/62841c991db345a1a932049c8b8c74f5
Autor:
Elodie Pronier, Aygun Imanci, Dorothée Selimoglu-Buet, Bouchra Badaoui, Raphael Itzykson, Thierry Roger, Chloé Jego, Audrey Naimo, Maëla Francillette, Marie Breckler, Orianne Wagner-Ballon, Maria E. Figueroa, Marine Aglave, Daniel Gautheret, Françoise Porteu, Olivier A. Bernard, William Vainchenker, François Delhommeau, Eric Solary, Nathalie M. Droin
Publikováno v:
Communications Biology
Communications Biology, 2022, 5 (1), pp.110. ⟨10.1038/s42003-022-03057-w⟩
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Communications biology, vol. 5, no. 1, pp. 110
Communications Biology, 2022, 5 (1), pp.110. ⟨10.1038/s42003-022-03057-w⟩
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Communications biology, vol. 5, no. 1, pp. 110
Somatic mutation in TET2 gene is one of the most common clonal genetic events detected in age-related clonal hematopoiesis as well as in chronic myelomonocytic leukemia (CMML). In addition to being a pre-malignant state, TET2 mutated clones are assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838ef036472ee8a0eb0a07bfde811fbb
https://hal.sorbonne-universite.fr/hal-03560437/file/s42003-022-03057-w.pdf
https://hal.sorbonne-universite.fr/hal-03560437/file/s42003-022-03057-w.pdf
Autor:
Laurence Kraus-Berthier, Lucie Laplane, Véronique Saada, Céline Berthon, Maria E. Figueroa, Bouchra Badaoui, Margaux Sevin, Franck Debeurme, Eric Padron, Thorsten Braun, Qin Yang, Nathalie Droin, Raphael Itzykson, Guido Kroemer, Dorothée Selimoglu-Buet, Eric Solary, Oliver Kepp, Margot Morabito, Alix Derreal, Hannah Newman, Sylvain Thepot, Gabriel Etienne, Miguel Torres-Martin, Sébastien Banquet, Severine Badel, Orianne Wagner-Ballon, Pierre Fenaux
Publikováno v:
Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩
Mouse models of chronic myeloid malignancies suggest that targeting mature cells of the malignant clone disrupts feedback loops that promote disease expansion. Here, we show that in chronic myelomonocytic leukemia (CMML), monocytes that accumulate in