Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dorothée Le Garrec"'
Autor:
Dana Palusova, Laibin Luo, Dorothée Le Garrec, Sandra Gori, David Lessard, J. Robert Sneyd, Francois Ravenelle, Damon Smith
Publikováno v:
Pharmaceutical Research. 25:313-319
Propofol is a water-insoluble intravenous anesthetic agent that is actually formulated as a water-in-oil emulsion with known drawbacks such as pain on injection, microorganism growth support and stability. We report on the properties of formulations
Autor:
Maxime Ranger, David Lessard, Stephen Rimmer, Dorothée Le Garrec, Sandra Gori, Jean-Christophe Leroux, Damon Smith, Laibin Luo
Publikováno v:
Macromolecules. 37:4008-4013
Low molecular weight poly(N-vinylpyrrolidone) (PVP) with a hydroxyl group at one end was successfully synthesized by free radical polymerization of N-vinyl-2-pyrrolidone (NVP). Using isopropyl alcohol as solvent and 2-mercaptoethanol as chain transfe
Publikováno v:
American Journal of Drug Delivery. 2:15-42
In recent years, the development of micelle-based carriers for cancer chemotherapy has been the object of growing scientific interest, both in academia and the pharmaceutical industry. Micelles have attracted attention in drug formulation and targeti
Autor:
Abdellatif Chenite, Matthew Shive, Mohammed Berrada, Dorothée Le Garrec, Jean-Christophe Leroux, Eve Ruel-Gariépy, Ali Bichara
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 57:53-63
A novel injectable thermosensitive in situ gelling hydrogel has been developed. The system, which falls under the BST-Gel platform technology developed at Biosyntech Inc. (Laval, QC, Canada), consists of a chitosan solution (C) neutralized with beta-
Publikováno v:
Journal of Controlled Release. 72:71-84
Hydrophobically-modified copolymers of N-isopropylacrylamide bearing a pH-sensitive moiety were investigated for the preparation of pH-responsive liposomes and polymeric micelles. The copolymers having the hydrophobic anchor randomly distributed with
Autor:
Dana Palusova, Corinne Benquet, David Lessard, Mohamad Nasser‐Eddine, Piotr Kujawa, Dorothée Le Garrec, Damon Smith, Michèle Parisien, Wilms Baille
Publikováno v:
Molecular Cancer Therapeutics. 8:C218-C218
Background: Novel formulations of SN38 were developed and screened in vitro. The efficacy and tolerability of the best formulation was evaluated in vivo. SN38 is the active metabolite of irinotecan (CPT-11) a potent TOPO-I inhibitor. Despite its poor
Autor:
François Ravenelle, Sandra Gori, Dorothée Le Garrec, David Lessard, Laibin Luo, Dana Palusova, J. Sneyd, Damon Smith
Publikováno v:
Pharmaceutical Research; Feb2008, Vol. 25 Issue 2, p313-319, 7p