Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dorothée Bourges"'
Autor:
Andrew S Brown, Chao Yang, Ka Yee Fung, Annabell Bachem, Dorothée Bourges, Sammy Bedoui, Elizabeth L Hartland, Ian R van Driel
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005691 (2016)
Legionella pneumophila is the causative agent of Legionnaires' disease, a potentially fatal lung infection. Alveolar macrophages support intracellular replication of L. pneumophila, however the contributions of other immune cell types to bacterial ki
Externí odkaz:
https://doaj.org/article/462e61b3197d46818e1ddcf884236d0b
Autor:
Alexandre Tang, Laurent Gauthier, Jochen Beninga, Benjamin Rossi, Nicolas Gourdin, Audrey Blanchard-Alvarez, Céline Amara, Jacqueline Courta, Alexandra Basset, Dorothée Bourges, Alexandre Desjonqueres, Emmanuelle Menoret, Catherine Pellat-Deceunynck, Philippe Moreau, Yannis Morel, Marielle Chiron, Eric Vivier, Angela Virone-Oddos
Publikováno v:
Cancer Research. 83:2960-2960
Multiple Myeloma (MM) is the second most prevalent hematopoietic malignancy, representing 10% of total blood cancers. Despite the emergence of new therapies, it is still an incurable disease. Safe, potent and innovative approaches with long lasting b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a037ddccbedaf8134afaf91f82c7a2f7
https://doi.org/10.1158/1538-7445.am2023-2960
https://doi.org/10.1158/1538-7445.am2023-2960
Autor:
Pauline Rettman, Dorothée Bourges, Laure-Marie Meyer, Ravi Rangara, Anna Ponchet-Lac, Nicolas Moindrot, Sukhvinder Sidhu, Céline Nicolazzi
Publikováno v:
Cancer Research. 82:4247-4247
Novel immunotherapeutic strategies targeting Natural Killer (NK) cells using monoclonal or multi-specific antibodies and immune modulator molecules are under development and there is a pressing need to have suitable mouse models for the evaluation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::848d081d64dd4211fa0138fba220b270
https://doi.org/10.1158/1538-7445.am2022-4247
https://doi.org/10.1158/1538-7445.am2022-4247
Autor:
Christophe Henry, Philippe Péron, Anne-Marie Blanchet, Arielle Genevois-Borella, Marc Trellu, Dorothée Bourges, Philippe Lienard, Alexandra Basset, Erwan Jouannot, Christophe Philippo, Laurent Debussche, Jürgen Moll
Publikováno v:
Cancer Research. 82:130-130
xCT is a cystine/glutamate antiporter that exports intracellular glutamate for extracellular cystine. In the intracellular space, cystine is converted into cysteine which is subsequently used for glutathione (GSH) synthesis (a major antioxidant speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be340049e3251319a582741903a08969
https://doi.org/10.1158/1538-7445.am2022-130
https://doi.org/10.1158/1538-7445.am2022-130
Publikováno v:
European Journal of Immunology. 44:2048-2058
The expression of the Ikaros transcription factor family member, Helios, has been shown to be associated with T-cell tolerance in both the thymus and the periphery. To better understand the importance of Helios in tolerance pathways, we have examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8f0dcfc158a93bf99ad2df193f58dd
https://doi.org/10.1002/eji.201343999
https://doi.org/10.1002/eji.201343999
Autor:
Paul A. Gleeson, Dorothée Bourges, Simon Read, Ellen M. Ross, Louis Boon, Fiona J. Houghton, Ian R. van Driel, Sammy Bedoui, Stacey M. Allen
Publikováno v:
The Journal of Immunology. 192:5023-5030
It has been proposed that activation of dendritic cells (DCs) presenting self-antigens during inflammation may lead to activation of autoreactive T cells and the development of autoimmunity. To test this hypothesis, we examined the presentation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf86a36106af970bd49951ed568b8bb
https://doi.org/10.4049/jimmunol.1303429
https://doi.org/10.4049/jimmunol.1303429
Publikováno v:
European Journal of Immunology. 43:1286-1296
Autoimmune disease can be prevented with immunosuppressive agents; however, the effectiveness of these treatments in advanced stage of disease and the fate of pathogenic T cells following such treatments are not clear. In this study we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ee9706c6707c9e127a7932f02d02b8
https://doi.org/10.1002/eji.201242771
https://doi.org/10.1002/eji.201242771
Publikováno v:
European journal of immunology. 47(1)
How the immune system maintains peripheral tolerance under inflammatory conditions is poorly understood. Here we assessed the fate of gastritogenic T cells following inflammatory activation in vivo. Self-reactive T cells (A23 T cells) specific for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b2d85ddab0d8a19e4824ff5bf7eab9
https://pubmed.ncbi.nlm.nih.gov/27759162
https://pubmed.ncbi.nlm.nih.gov/27759162
Publikováno v:
Immunology & Cell Biology. 89:60-69
Selection of T cells does not end with events in the thymus, but continues in extrathymic tissues and for the life of the organism. In this review, we examine how self-reactive T cells are rendered harmless and the processes that select for T cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4102b0bd734821d770c693c3703b3d
https://doi.org/10.1038/icb.2010.133
https://doi.org/10.1038/icb.2010.133
Autor:
Michelle Kelly, Paul J. Hertzog, Dorothée Bourges, Desmond K. Y. Ang, Louis Boon, Ian R. van Driel, Fiona M. Sansom, Ralf Schuelein, Claire Vl Oates, Elizabeth L. Hartland
Publikováno v:
The Journal of Immunology. 184:5429-5433
Plasmacytoid dendritic cells (pDCs) are well known as the major cell type that secretes type I IFN in response to viral infections. Their role in combating other classes of infectious organisms, including bacteria, and their mechanisms of action are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e43be421e0bf7037557537ce69f4ce2
https://doi.org/10.4049/jimmunol.1000128
https://doi.org/10.4049/jimmunol.1000128