Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Dorothé e Deppe"'
Autor:
Antonio Pezzutto, Saskia Meyer, Dorothé e Deppe, Regina Fertig, Sandra Lüttgau, Oliver Schmetzer, Hossein Panjideh, Frank Breitling, Martin Lipp, Gerhard Moldenhauer
Publikováno v:
Antibodies, Vol 2, Iss 2, Pp 338-352 (2013)
Antibodies
Volume 2
Issue 2
Pages 338-352
Antibodies
Volume 2
Issue 2
Pages 338-352
Using genetic engineering a humanized Fab fragment with specificity for CD19 was fused to a disulfide-stabilized single-chain antibody (dsFv) recognizing CD5. This format should show reduced immunogenicity and improved tissue penetration. The specifi