Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Doroteya Raykova"'
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Determining the levels of protein–protein interactions is essential for the analysis of signaling within the cell, characterization of mutation effects, protein function and activation in health and disease, among others. Herein, we descri
Externí odkaz:
https://doaj.org/article/62ebc0c6a0da437aba3d465a5bbe05c2
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1b52ed4d7464442c978e7ac4bff1d6a2
Autor:
Axel Klaesson, Karin Grannas, Tonge Ebai, Johan Heldin, Björn Koos, Mattias Leino, Doroteya Raykova, Johan Oelrich, Linda Arngården, Ola Söderberg, Ulf Landegren
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract We have redesigned probes for in situ proximity ligation assay (PLA), resulting in more efficient localized detection of target proteins. In situ PLA depends on recognition of target proteins by pairs of antibody-oligonucleotide conjugates (
Externí odkaz:
https://doaj.org/article/75ad5875c3544fa48fd0da457da9bb4f
Autor:
Doroteya Raykova, Joakim Klar, Aysha Azhar, Tahir Naeem Khan, Naveed Altaf Malik, Muhammad Iqbal, Muhammad Tariq, Shahid Mahmood Baig, Niklas Dahl
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93607 (2014)
Pure hair and nail ectodermal dysplasia (PHNED) comprises a heterogeneous group of rare heritable disorders characterized by brittle hair, hypotrichosis, onychodystrophy and micronychia. Autosomal recessive (AR) PHNED has previously been associated w
Externí odkaz:
https://doaj.org/article/be1adbe3ffec4a89b125b16f67381000
Autor:
Doroteya Raykova, Björn Koos, Anna Asplund, Márton Gelléri, Ylva Ivarsson, U. Helena Danielson, Ola Söderberg
Publikováno v:
Proteomes, Vol 4, Iss 4, p 36 (2016)
The invention of the microscope has been fundamental for the understanding of tissue architecture and subcellular structures. With the advancement of higher magnification microscopes came the development of various molecular biology tools such as Fö
Externí odkaz:
https://doaj.org/article/1dd337435fc94abc89d7eaed55b5cc76
The interplay between membrane subregions and receptor tyrosine kinases (RTK) will influence signaling in both normal and pathological RTK conditions. In this study, epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636bc6419c62bab23df924d024ca3de3
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-506912
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-506912
Publikováno v:
Cancer Research. 83:6372-6372
Immune checkpoints (ICs), which are inhibitory signaling pathways that can down-modulate the immune responses of T cells, are pivotal in peripheral tissues and for maintaining immune self-tolerance. Among the many molecularly defined IC proteins, som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::389d3c7a2d9c261a3b66e570385c084e
https://doi.org/10.1158/1538-7445.am2023-6372
https://doi.org/10.1158/1538-7445.am2023-6372
Publikováno v:
Cancer Research. 83:6772-6772
Immunofluorescent staining of tissues via in situ proximity ligation assay (isPLA) is now a well-established tool for highly sensitive detection of protein-protein interactions and their localization. It finds versatile applications in basic research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6346df41e9ba2319f5174d276c84181a
https://doi.org/10.1158/1538-7445.am2023-6772
https://doi.org/10.1158/1538-7445.am2023-6772
Autor:
Bjoern Koos, Ola Söderberg, Johan Heldin, Mattias Leino, Marie Rubin Sander, Despoina Kermpatsou, Doroteya Raykova
Publikováno v:
Molecular Systems Design & Engineering. 4:1058-1065
Proximity based detection methods are invaluable tools in the field of molecular biology, increasing selectivity and allowing for analysis of protein interactions. ProxHCR utilizes pairs of antibodies labelled with oligonucleotides to probe for proxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75638cfc3471a1e314a1f3ee775afe5d
https://doi.org/10.1039/c9me00079h
https://doi.org/10.1039/c9me00079h
Autor:
Felipe Marques Souza de Oliveira, Benjamin Siart, Celso A. Reis, Karol Polom, Johan Heldin, Masood Kamali-Moghaddam, Stefan Mereiter, Niclas G. Karlsson, Doroteya Raykova, Franco Roviello, Qiujin Shen, Peter Lönn
Publikováno v:
New Biotechnology. 45:51-59
Post-translational modifications (PTMs) regulate protein activities to help orchestrate and fine-tune cellular processes. Dysregulation of PTMs is often related with disorders and malignancies, and may serve as a precise biomarker of disease. Develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010eda653f8bfa8c9713bfd95dfd3883
https://doi.org/10.1016/j.nbt.2017.10.005
https://doi.org/10.1016/j.nbt.2017.10.005