Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Dorotenko A"'
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 30, Iss 4, Pp 32-42 (2024)
Introduction. Phosphodiesterases (PDEs) are a group of enzymes that hydrolyze the phosphodiester bond in cyclic nucleotides. PDE10A is mainly present in the medium-sized spiny neurons of the striatum. Functionally, PDE10A inhibition imitates the effe
Externí odkaz:
https://doaj.org/article/2adc4be348b142bab3a05297061c706c
Autor:
A. N. Arevefa, A. R. Dorotenko, S. M. Noskov, I. E. Makarenko, R. V. Drai, T. N. Komarov, O. A. Archakova, N. S. Bagaeva, I. E. Shokhin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 3, Pp 218-227 (2023)
Introduction. Citicoline is an endogenous nucleoside consisting of cytidine and choline linked by a diphosphate bridge that is involved in the synthesis of membrane phospholipids. Drugs containing citicoline have neuroprotective and neurometabolic ef
Externí odkaz:
https://doaj.org/article/ccf7fc38cfed460b835470037a54f63e
Autor:
Igor Makarenko, Artem Dorotenko, Sergey Noskov, Veniamin Banko, Valeria Saparova, Alexandr Khokhlov, Evgeniia Zoreeva, Andrey Nedorubov, Bella Zinnatulina, Maria Gefen, Roman Drai
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Aims The pharmacodynamic (PD) similarity between GP40141, a proposed romiplostim biosimilar, and reference romiplostim was evaluated. Pharmacokinetics and safety were also assessed. Methods In this phase 1, randomized, double‐blind, single
Externí odkaz:
https://doaj.org/article/e6fff10272504c27af32e229a159a688
Autor:
Dorotenko, Artem1 (AUTHOR), Makarenko, Igor1 (AUTHOR), Karonova, Tatiana2 (AUTHOR), Protsenko, Ekaterina1 (AUTHOR) ekaterina.protsenko@geropharm.com, Gefen, Maria1 (AUTHOR), Galstyan, Gagik3 (AUTHOR), Antonova, Elizaveta4 (AUTHOR), Shitov, Leonid5 (AUTHOR), Dzhurko, Yurij5 (AUTHOR), Drai, Roman1 (AUTHOR)
Publikováno v:
Clinical Pharmacology in Drug Development. Dec2023, Vol. 12 Issue 12, p1178-1184. 7p.
Autor:
Makarenko, Igor1,2 (AUTHOR), Dorotenko, Artem1,3 (AUTHOR), Noskov, Sergey4 (AUTHOR), Banko, Veniamin1 (AUTHOR) veniamin.banko@geropharm.com, Saparova, Valeria1,2 (AUTHOR), Khokhlov, Alexandr5 (AUTHOR), Zoreeva, Evgeniia1 (AUTHOR), Nedorubov, Andrey6 (AUTHOR), Zinnatulina, Bella1 (AUTHOR), Gefen, Maria1 (AUTHOR), Drai, Roman1 (AUTHOR)
Publikováno v:
Pharmacology Research & Perspectives. Oct2023, Vol. 11 Issue 5, p1-8. 8p.
Autor:
Koksharova, Ekaterina, Drai, Roman, Noskov, Sergei, Dorotenko, Artem, Protsenko, Ekaterina, Radaeva, Kseniia, Arefeva, Anna, Gefen, Maria, Galstyan, Gagik, Makarenko, Igor
Publikováno v:
Clinical Pharmacology in Drug Development; Jul2024, Vol. 13 Issue 7, p828-836, 9p
Autor:
Sukhanov, Ilya1,2 (AUTHOR) ilia.sukhanov@gmail.com, Dorotenko, Artem1 (AUTHOR), Fesenko, Zoia2 (AUTHOR), Savchenko, Artem1 (AUTHOR), Efimova, Evgeniya V.2 (AUTHOR), Mor, Mikael S.2 (AUTHOR), Belozertseva, Irina V.1 (AUTHOR), Sotnikova, Tatyana D.2 (AUTHOR), Gainetdinov, Raul R.2,3 (AUTHOR) ilia.sukhanov@gmail.com
Publikováno v:
Biomolecules (2218-273X). Jan2023, Vol. 13 Issue 1, p9. 13p.
Autor:
Ilya Sukhanov, Artem Dorotenko, Zoia Fesenko, Artem Savchenko, Evgeniya V. Efimova, Mikael S. Mor, Irina V. Belozertseva, Tatyana D. Sotnikova, Raul R. Gainetdinov
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 9 (2022)
Parkinson’s disease is the second most common neurodegenerative pathology. Due to the limitations of existing therapeutic approaches, novel anti-parkinsonian medicines with non-dopamine mechanisms of action are clearly needed. One of the promising
Externí odkaz:
https://doaj.org/article/c1b30259947a4a0a93e8ff23764eb869
Autor:
Sukhanov, Ilya, Dorotenko, Artem, Dolgorukova, Antonina, Hoener, Marius C., Gainetdinov, Raul R., Bespalov, Anton Yu.
Publikováno v:
In Neuropharmacology January 2019 144:184-192
Autor:
Denis V Kurkin, Dmitry A Bakulin, Evgeny I Morkovin, Anna V Kalatanova, Igor E Makarenko, Artem R Dorotenko, Nikolay S Kovalev, Marina A Dubrovina, Dmitry V Verkholyak, Elizaveta E Abrosimova, Alexey V Smirnov, Maksim V Shmidt, Ivan N Tyurenkov
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254493 (2021)
This study was the first to compare the neuroprotective activity of Cerebrolysin®, Actovegin® and Cortexin® in rodent models of acute and chronic brain ischemia. The neuroprotective action was evaluated in animals with acute (middle cerebral arter
Externí odkaz:
https://doaj.org/article/e345af691eb64e8cace1bedfb00ef977