Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dorota Wrzesniok"'
Autor:
Zuzanna Rzepka, Katarzyna Bober-Majnusz, Justyna Magdalena Hermanowicz, Ewa Bębenek, Elwira Chrobak, Arkadiusz Surażyński, Dorota Wrześniok
Publikováno v:
Molecules, Vol 29, Iss 18, p 4408 (2024)
There are scientific studies indicating that the attachment of an indole moiety to the triterpene scaffold can lead to increased anticancer potential. Lipophilicity is one of the factors that may influence biological properties and is therefore an im
Externí odkaz:
https://doaj.org/article/64e0f48da4c4401e91b60c5b86c70202
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9571 (2024)
Cladosporium cladosporioides are the pigmented soil fungi containing melanin. The aim of this work was to determine the influence of amphotericin B on free radicals in the natural melanin isolated from pigmented fungi Cladosporium cladosporioides and
Externí odkaz:
https://doaj.org/article/f197179e3baf414db7751cfc130f308b
Autor:
Justyna Kowalska, Dorota Wrześniok
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 847 (2024)
Type 2 diabetes (T2DM) is a chronic metabolic disease with a steadily increasing prevalence worldwide. Diabetes affects the function of many organs, including the skin. Pharmacotherapy for T2DM is mainly based on oral hypoglycemic drugs. The therapeu
Externí odkaz:
https://doaj.org/article/4430f68fa43b4e29b66ee518a160fd1d
Autor:
Ewa Bębenek, Zuzanna Rzepka, Justyna Magdalena Hermanowicz, Elwira Chrobak, Arkadiusz Surażyński, Artur Beberok, Dorota Wrześniok
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4517 (2024)
Betulonic acid (B(O)A) is a pentacyclic lupane-type triterpenoid that widely exists in plants. There are scientific reports indicating anticancer activity of B(O)A, as well as the amides and esters of this triterpenoid. In the first step of the study
Externí odkaz:
https://doaj.org/article/9130336aeaee4e9a85cb4c39c71663b7
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 521 (2024)
Melanins are biopolymeric pigments formed by a multi-step oxidation process of tyrosine in highly specialized cells called melanocytes. Melanin pigments are mainly found in the skin, iris, hair follicles, and inner ear. The photoprotective properties
Externí odkaz:
https://doaj.org/article/e7b78ff275cc46389e91966eba7bb847
Autor:
Marta Karkoszka, Jakub Rok, Zuzanna Rzepka, Klaudia Banach, Justyna Kowalska, Dorota Wrześniok
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1432 (2024)
Hypertension is known to be a multifactorial disease associated with abnormalities in neuroendocrine, metabolic, and hemodynamic systems. Poorly controlled hypertension causes more than one in eight premature deaths worldwide. Hydrochlorothiazide (HC
Externí odkaz:
https://doaj.org/article/db615dacde114270985d079d647510b6
Publikováno v:
Farmacja Polska, Vol 78, Iss 2, Pp 59-65 (2022)
The proper operation of the nervous system is strongly dependent on the interactions between neurons and glial cells. Thus, the disturbance of their relationship leads to various neurological complications. Pathological changes associated with glia,
Externí odkaz:
https://doaj.org/article/229f2ca5c7544690bd68758a65842ecc
Autor:
Marta Karkoszka, Jakub Rok, Klaudia Banach, Justyna Kowalska, Zuzanna Rzepka, Dorota Wrześniok
Publikováno v:
Molecules, Vol 27, Iss 13, p 4215 (2022)
Meloxicam (MLX), which belongs to the oxicam nonsteroidal anti-inflammatory drug derivatives, is an inhibitor of the cyclooxygenase-2 (COX-2) enzyme. Cutaneous adverse effects caused by interaction between UVA radiation and exogenous factors can mani
Externí odkaz:
https://doaj.org/article/985d12b18eba4e6da3a5cf51ab0a9d98
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 831 (2022)
Malignant melanoma is still a serious medical problem. Relatively high mortality, a still-growing number of newly diagnosed cases, and insufficiently effective methods of therapy necessitate melanoma research. Tetracyclines are compounds with pleiotr
Externí odkaz:
https://doaj.org/article/4e1f5e24f8f14c5d9b09f00d2fbba10e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11966 (2021)
Malignant melanoma is responsible for the majority of skin cancer-related deaths. The methods of cancer treatment include surgical removal, chemotherapy, immunotherapy, and targeted therapy. However, neither of these methods gives satisfactory result
Externí odkaz:
https://doaj.org/article/e3ea8656673249caa07738f09854b431