Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Dorota Wloga"'
Autor:
Avrin Ghanaeian, Sumita Majhi, Caitlyn L. McCafferty, Babak Nami, Corbin S. Black, Shun Kai Yang, Thibault Legal, Ophelia Papoulas, Martyna Janowska, Melissa Valente-Paterno, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein regulatory complex (N-DRC), which links adjacent
Externí odkaz:
https://doaj.org/article/0caf9d6c54f2470f93614bf623443134
Autor:
Shintaroh Kubo, Corbin S. Black, Ewa Joachimiak, Shun Kai Yang, Thibault Legal, Katya Peri, Ahmad Abdelzaher Zaki Khalifa, Avrin Ghanaeian, Caitlyn L. McCafferty, Melissa Valente-Paterno, Chelsea De Bellis, Phuong M. Huynh, Zhe Fan, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cilia are ubiquitous eukaryotic organelles responsible for cellular motility and sensory functions. The ciliary axoneme is a microtubule-based cytoskeleton consisting of two central singlets and nine outer doublet microtubules. Cryo-electron
Externí odkaz:
https://doaj.org/article/3b866ad18ed6419bafadde4fb6563a61
Autor:
Ewa Joachimiak, Anna Osinka, Hanan Farahat, Bianka Świderska, Ewa Sitkiewicz, Martyna Poprzeczko, Hanna Fabczak, Dorota Wloga
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Motile cilia are ultrastructurally complex cell organelles with the ability to actively move. The highly conserved central apparatus of motile 9 × 2 + 2 cilia is composed of two microtubules and several large microtubule-bound projections,
Externí odkaz:
https://doaj.org/article/9861cc43595b45b9b2d7045943a7c04b
Autor:
Khodor S. Hazime, Zhu Zhou, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Wloga, Jarema J. Malicki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport (IFT)-dependent trafficking of proteins to and from cilia. Before entering the ciliary co
Externí odkaz:
https://doaj.org/article/ad03647e47844e35a88866b74e826023
Autor:
Jan Pyrih, Vojtěch Žárský, Justin D. Fellows, Christopher Grosche, Dorota Wloga, Boris Striepen, Uwe G. Maier, Jan Tachezy
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Nbp35-like proteins (Nbp35, Cfd1, HCF101, Ind1, and AbpC) are P-loop NTPases that serve as components of iron-sulfur cluster (FeS) assembly machineries. In eukaryotes, Ind1 is present in mitochondria, and its function is associate
Externí odkaz:
https://doaj.org/article/614cb09431204a6ea3555c71870cddf4
Autor:
Marta Bicka, Ewa Joachimiak, Paulina Urbanska, Anna Osinka, Anna Konopka, Ewa Bulska, Dorota Wloga
Publikováno v:
Cells, Vol 11, Iss 24, p 4048 (2022)
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 +
Externí odkaz:
https://doaj.org/article/04e0ba66b5f54e48a5f97c57320b6b21
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009388 (2021)
Ciliary beating requires the coordinated activity of numerous axonemal complexes. The protein composition and role of radial spokes (RS), nexin links (N-DRC) and dyneins (ODAs and IDAs) is well established. However, how information is transmitted fro
Externí odkaz:
https://doaj.org/article/9a5efe4abd4d4820bb5909d5812c9c4f
Autor:
Khodor S. Hazime, Zhu Zhou, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Wloga, Jarema J. Malicki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/dfadd61adafc432196fed76392b57561
Autor:
Michal Niziolek, Marta Bicka, Anna Osinka, Zuzanna Samsel, Justyna Sekretarska, Martyna Poprzeczko, Rafal Bazan, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1749 (2022)
Primary ciliary dyskinesia (PCD) is a hereditary genetic disorder caused by the lack of motile cilia or the assembxly of dysfunctional ones. This rare human disease affects 1 out of 10,000–20,000 individuals and is caused by mutations in at least 5
Externí odkaz:
https://doaj.org/article/a049733c3b7f4c568bd70c96fc5ef2d3
Autor:
Yu-Yang Jiang, Wolfgang Maier, Ralf Baumeister, Gregory Minevich, Ewa Joachimiak, Dorota Wloga, Zheng Ruan, Natarajan Kannan, Stephen Bocarro, Anoosh Bahraini, Krishna Kumar Vasudevan, Karl Lechtreck, Eduardo Orias, Jacek Gaertig
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008099 (2019)
The length of cilia is controlled by a poorly understood mechanism that involves members of the conserved RCK kinase group, and among them, the LF4/MOK kinases. The multiciliated protist model, Tetrahymena, carries two types of cilia (oral and locomo
Externí odkaz:
https://doaj.org/article/753481e22e20497f8098f4e113e37156