Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Dorota Wloga"'
Autor:
Avrin Ghanaeian, Sumita Majhi, Caitlyn L. McCafferty, Babak Nami, Corbin S. Black, Shun Kai Yang, Thibault Legal, Ophelia Papoulas, Martyna Janowska, Melissa Valente-Paterno, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein regulatory complex (N-DRC), which links adjacent
Externí odkaz:
https://doaj.org/article/0caf9d6c54f2470f93614bf623443134
Autor:
Shintaroh Kubo, Corbin S. Black, Ewa Joachimiak, Shun Kai Yang, Thibault Legal, Katya Peri, Ahmad Abdelzaher Zaki Khalifa, Avrin Ghanaeian, Caitlyn L. McCafferty, Melissa Valente-Paterno, Chelsea De Bellis, Phuong M. Huynh, Zhe Fan, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cilia are ubiquitous eukaryotic organelles responsible for cellular motility and sensory functions. The ciliary axoneme is a microtubule-based cytoskeleton consisting of two central singlets and nine outer doublet microtubules. Cryo-electron
Externí odkaz:
https://doaj.org/article/3b866ad18ed6419bafadde4fb6563a61
Autor:
Ewa Joachimiak, Anna Osinka, Hanan Farahat, Bianka Świderska, Ewa Sitkiewicz, Martyna Poprzeczko, Hanna Fabczak, Dorota Wloga
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Motile cilia are ultrastructurally complex cell organelles with the ability to actively move. The highly conserved central apparatus of motile 9 × 2 + 2 cilia is composed of two microtubules and several large microtubule-bound projections,
Externí odkaz:
https://doaj.org/article/9861cc43595b45b9b2d7045943a7c04b
Autor:
Khodor S. Hazime, Zhu Zhou, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Wloga, Jarema J. Malicki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport (IFT)-dependent trafficking of proteins to and from cilia. Before entering the ciliary co
Externí odkaz:
https://doaj.org/article/ad03647e47844e35a88866b74e826023
Autor:
Jan Pyrih, Vojtěch Žárský, Justin D. Fellows, Christopher Grosche, Dorota Wloga, Boris Striepen, Uwe G. Maier, Jan Tachezy
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Nbp35-like proteins (Nbp35, Cfd1, HCF101, Ind1, and AbpC) are P-loop NTPases that serve as components of iron-sulfur cluster (FeS) assembly machineries. In eukaryotes, Ind1 is present in mitochondria, and its function is associate
Externí odkaz:
https://doaj.org/article/614cb09431204a6ea3555c71870cddf4
Autor:
Marta Bicka, Ewa Joachimiak, Paulina Urbanska, Anna Osinka, Anna Konopka, Ewa Bulska, Dorota Wloga
Publikováno v:
Cells, Vol 11, Iss 24, p 4048 (2022)
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 +
Externí odkaz:
https://doaj.org/article/04e0ba66b5f54e48a5f97c57320b6b21
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009388 (2021)
Ciliary beating requires the coordinated activity of numerous axonemal complexes. The protein composition and role of radial spokes (RS), nexin links (N-DRC) and dyneins (ODAs and IDAs) is well established. However, how information is transmitted fro
Externí odkaz:
https://doaj.org/article/9a5efe4abd4d4820bb5909d5812c9c4f
Autor:
Khodor S. Hazime, Zhu Zhou, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Wloga, Jarema J. Malicki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/dfadd61adafc432196fed76392b57561
Autor:
Michal Niziolek, Marta Bicka, Anna Osinka, Zuzanna Samsel, Justyna Sekretarska, Martyna Poprzeczko, Rafal Bazan, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1749 (2022)
Primary ciliary dyskinesia (PCD) is a hereditary genetic disorder caused by the lack of motile cilia or the assembxly of dysfunctional ones. This rare human disease affects 1 out of 10,000–20,000 individuals and is caused by mutations in at least 5
Externí odkaz:
https://doaj.org/article/a049733c3b7f4c568bd70c96fc5ef2d3
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3013 (2021)
Motile cilia and homologous organelles, the flagella, are an early evolutionarily invention, enabling primitive eukaryotic cells to survive and reproduce. In animals, cilia have undergone functional and structural speciation giving raise to typical m
Externí odkaz:
https://doaj.org/article/0d89f663c8454afdb6636c8fba1a6527