Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Dorota Olender"'
Autor:
Dorota Olender, Jacek Kujawski, Bartosz Skóra, Ewa Baranowska-Wójcik, Katarzyna Sowa-Kasprzak, Anna Pawełczyk, Lucjusz Zaprutko, Dominik Szwajgier, Konrad A. Szychowski
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37147- (2024)
In the area of research on neurodegenerative diseases, the current challenge is to search for appropriate research methods that would detect these diseases at the earliest possible stage, but also new active structures that would reduce the rate of t
Externí odkaz:
https://doaj.org/article/995f3b675c004e84a564ff285bc4a5f5
Autor:
Dorota Olender, Anna Pawełczyk, Anna Leśków, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, Dorota Diakowska
Publikováno v:
Molecules, Vol 29, Iss 21, p 5171 (2024)
Chalcone is an aromatic ketone that forms the central core of many important biological compounds. Chalcone derivatives show various biological activities, especially anti-inflammatory, antibacterial, antioxidant, and anticancer activities, and also
Externí odkaz:
https://doaj.org/article/467b44641eac4286af7a48437e0521b3
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 2, Pp 289-304 (2023)
Synthesis and biological evaluation of hybrid molecules combining naturally occurring antioxidant active structures with anti-inflammatory agents has been a strong trend in medicinal chemistry. This study focuses on modulating the structure of curcum
Externí odkaz:
https://doaj.org/article/0cd05eb874de4eaeb8e4a92051092bce
Autor:
Dorota Olender, Małgorzata Józkowiak, Hanna Piotrowska-Kempisty, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, Izabela Muszalska-Kolos, Ewa Baranowska-Wójcik, Dominik Szwajgier
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1331 (2023)
The primary purpose of this work was to design and obtain a series of curcuminoid chalcone–NSAID hybrid derivatives. The ester-type hybrid compounds with ibuprofen (i), ketoprofen (ii), and naproxen (iii) were obtained in two ways, using the Claise
Externí odkaz:
https://doaj.org/article/1c40bdcfe0f84747bec7db16c0b01d74
Autor:
Katarzyna Sowa-Kasprzak, Małgorzata Józkowiak, Dorota Olender, Anna Pawełczyk, Hanna Piotrowska-Kempisty, Lucjusz Zaprutko
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 2008 (2023)
Sonodynamic therapy (SDT) is a non-invasive therapeutic modality in cancer treatment that combines low-intensity ultrasound (US) and sonosensitizers. Tumor cells are destroyed through the synergistic effects of ultrasound and a chemical sonosensitize
Externí odkaz:
https://doaj.org/article/ac8927aa35654a3dbf0f0d5c348fb4d0
Autor:
Katarzyna Sowa-Kasprzak, Ewa Totoń, Jacek Kujawski, Dorota Olender, Natalia Lisiak, Lucjusz Zaprutko, Błażej Rubiś, Mariusz Kaczmarek, Anna Pawełczyk
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1506 (2023)
Curcumin and oleanolic acid are natural compounds with high potential in medicinal chemistry. These products have been widely studied for their pharmacological properties and have been structurally modified to improve their bioavailability and therap
Externí odkaz:
https://doaj.org/article/a91466fc188d4fc5880a590827437644
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 12, Pp 8793-8806 (2020)
One of the tasks of modern medicinal chemistry is to produce new molecules that have interesting and desired biological effects. In addition, the synthetic procedure for obtaining these compounds should be at least partially smart and rational e.g.
Externí odkaz:
https://doaj.org/article/7086a700a57741a88c2deba296255504
Publikováno v:
Journal of Medical Science, Vol 88, Iss 1 (2019)
Nitroimidazoles have wide range of therapeutic uses mainly as anaerobic antibacterials and antiprotozoal agents. Some bicyclic nitroimidazodihydrooxazoles and nitroimidazotetrahydrooxazines are found to be antituberculosis agents. Hence, the biologic
Externí odkaz:
https://doaj.org/article/6c6b289f99344ae39182269f5fab8b7e
Publikováno v:
Molecules, Vol 23, Iss 9, p 2360 (2018)
Increasingly stringent regulations aimed at protection of the natural environment have stimulated the search for new synthetic methodologies in organic and medicinal chemistry having no or minimum harmful effect. An interesting approach is the use of
Externí odkaz:
https://doaj.org/article/c1ce4a45918f42f38c61cd5d3fd9e586
Publikováno v:
Pharmaceuticals, Vol 11, Iss 2, p 54 (2018)
The current concept in searching for new bioactive products, including mainly original active substances with potential application in pharmacy and medicine, is based on compounds with a previously determined structure, well-known properties, and bio
Externí odkaz:
https://doaj.org/article/ed4c425a505b4ae390acb5bcb88a62ea