Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dorota Matyszewska"'
Publikováno v:
Molecules, Vol 26, Iss 18, p 5483 (2021)
A model biomimetic system for the study of protein reconstitution or drug interactions should include lipid rafts in the mixed lipid monolayer, since they are usually the domains embedding membrane proteins and peptides. Four model lipid films compos
Externí odkaz:
https://doaj.org/article/580c5ed17f2b48ae80d576a7ac606986
Autor:
Dorota Matyszewska
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 7, Iss 1, Pp 524-532 (2016)
In this work the interactions of an anticancer drug daunorubicin (DNR) with model thiolipid layers composed of 1,2-dipalmitoyl-sn-glycero-3-phosphothioethanol (DPPTE) were investigated using Langmuir technique. The results obtained for a free drug we
Externí odkaz:
https://doaj.org/article/782d71fadb47463ca5fa61192be17c43
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 38(45)
For the first time, HMG-CoA reductase, the membrane protein responsible for cholesterol synthesis, was incorporated into a lipid membrane consisting of DOPC:Chol:SM at a 1:1:1 molar ratio, which mimics the lipid rafts of cell membranes. The membrane
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 226:113289
Publikováno v:
Molecules, Vol 26, Iss 5483, p 5483 (2021)
Molecules
Volume 26
Issue 18
Molecules
Volume 26
Issue 18
A model biomimetic system for the study of protein reconstitution or drug interactions should include lipid rafts in the mixed lipid monolayer, since they are usually the domains embedding membrane proteins and peptides. Four model lipid films compos
Publikováno v:
Electrochimica Acta. 305:204-211
The Na+/K+-ATPase pump was reconstituted in proteoliposomes composed of DPPC:DPPE, which were then spread at the air-water interface using Langmuir technique. In the presence of the enzyme in the liposomes the resulting lipidic layer at the air-water
Autor:
Dorota Matyszewska, Marcin Broniatowski, Aleksandra Bartkowiak, Renata Bilewicz, Michalina Zaborowska, Agata Krzak
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 204
In this work, the effects of simvastatin (SIM), (2-hydroxypropyl)-β-cyclodextrin (HPβCD) and their complex (SIM:HPβCD) on the structure and properties of lipid membranes were investigated for the first time by Langmuir technique combined with PM-I
Publikováno v:
Journal of Colloid and Interface Science
Publikováno v:
Journal of colloid and interface science. 581
We quantify directly here for the first time the extents of interactions of two different anthracycline drugs with pure and mixed lipid monolayers with respect to the surface pressure and elucidate differences in the resulting interaction mechanisms.