Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dorota Kubacka"'
Autor:
Anna Wojtczak, Renata Kasprzyk, Marcin Warmiński, Krystian Ubych, Dorota Kubacka, Pawel J. Sikorski, Jacek Jemielity, Joanna Kowalska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Fluorescence anisotropy (FA) is a powerful technique for the discovery of protein inhibitors in a high-throughput manner. In this study, we sought to develop new universal FA-based assays for the evaluation of compounds targeting mRNA 5′ c
Externí odkaz:
https://doaj.org/article/17b379a52296481f8cd837d1cb2a8f0d
Autor:
Dorota Kubacka, Mateusz Kozarski, Marek R. Baranowski, Radoslaw Wojcik, Joanna Panecka-Hofman, Dominika Strzelecka, Jerome Basquin, Jacek Jemielity, Joanna Kowalska
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 554 (2022)
Cytosolic nucleotidases (cNs) catalyze dephosphorylation of nucleoside 5’-monophosphates and thereby contribute to the regulation of nucleotide levels in cells. cNs have also been shown to dephosphorylate several therapeutically relevant nucleotide
Externí odkaz:
https://doaj.org/article/701c49d13e3344b1980ab9091cfae682
Autor:
Radoslaw Wojcik, Marek R. Baranowski, Lukasz Markiewicz, Dorota Kubacka, Marcelina Bednarczyk, Natalia Baran, Anna Wojtczak, Pawel J. Sikorski, Joanna Zuberek, Joanna Kowalska, Jacek Jemielity
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1941 (2021)
Dinucleotide analogs of the messenger RNA cap (m7GpppN) are useful research tools and have potential applications as translational inhibitors or reagents for modification of in vitro transcribed mRNAs. It has been previously reported that replacing t
Externí odkaz:
https://doaj.org/article/31081b992c5141aa820199bd8e43fc38
Autor:
Dorota Kubacka-Jasiecka
Publikováno v:
Rocznik Filozoficzny Ignatianum, Vol 22, Iss 1, Pp 51-89 (2016)
This study discusses the issue of emotional crisis and trauma in terms of opportunities to develop and grow. The article seeks to show the complex psychological conditions pertaining to emotional crises, a constructive way of dealing with them, and t
Externí odkaz:
https://doaj.org/article/4cf8731dbc524fb78b3bdc13315a2fae
Autor:
Dorota Kubacka, Anastasiia Kamenska, Helen Broomhead, Nicola Minshall, Edward Darzynkiewicz, Nancy Standart
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/189871aaedae4a3599ea25fc3c5eaa37
Autor:
Dorota Kubacka, Anastasiia Kamenska, Helen Broomhead, Nicola Minshall, Edward Darzynkiewicz, Nancy Standart
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72761 (2013)
In addition to the canonical eIF4E cap-binding protein, eukaryotes have evolved sequence-related variants with distinct features, some of which have been shown to negatively regulate translation of particular mRNAs, but which remain poorly characteri
Externí odkaz:
https://doaj.org/article/124348df34a54d1da0266382bd79e231
Autor:
Dorota Kubacka-Jasiecka
Publikováno v:
Psychologia Rozwojowa. 26:23-41
Applied Psychology –From Witmer to Modernity This work, inspired by the symbolic “centenary”of Polish psychology has been dedicated to the emergence and development of applied psychology. The main protagonist of applied psychology, and clinical
Autor:
Dorota Kubacka, Erdmann Spiecker, K. Beck, Sannakaisa Virtanen, H.-E. Zschau, S. P. Hagen, Mathias C. Galetz
Publikováno v:
Oxidation of Metals. 97:209-226
The oxidation resistance of novelγ/γ’-strengthened Co-base superalloys is clearly outmatched by their Ni-base counterparts within the high-temperature regime. Therefore, surface modification strategies to foster protective alumina growth seem aus
Publikováno v:
Scripta Materialia. 192:120-124
We present a new approach for the quantitative study of high-temperature diffusion in compositionally complex superalloys on the nano-scale. As key element, the approach utilizes the γ/γ'-microstructure itself as intrinsic nano-diffusion-couple (ND
Autor:
John D. Gross, Marcin Warminski, Pawel J. Sikorski, Jacek Jemielity, Marcin Nowotny, Renata Kasprzyk, Dorota Kubacka, Ryan W. Tibble, Joanna Kowalska, Elzbieta Nowak
Publikováno v:
ACS Chemical Biology
mRNA-based therapies and vaccines constitute a disruptive technology with the potential to revolutionize modern medicine. Chemically modified 5′ cap structures have provided access to mRNAs with superior translational properties that could benefit