Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dorota Klysz"'
Autor:
Katalin Sandor, Peng Xu, Jing Huang, Steven A Feldman, Nikolaos Gkitsas, Crystal L Mackall, Bence Daniel, Dorota Klysz, Malek Bashti, Elena Sotillo, Ansuman T Satpathy, Carley Fowler, Meena Malipatlolla, Lucille Stuani, Katherine A Freitas, Stefanie Meier, Louai Labanieh, Amaury Leruste, Janette Mata-Alcazar, Vimal Keerthi, Justin A Guerrero, Chris Fisher, Sunny Patel, Kyle Asano, Shabnum Patel, Kara L Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ac586e86c0cd4992806758a3b9aa88b7
Autor:
Katalin Sandor, Peng Xu, Joseph A Fraietta, Stephan Grupp, Crystal L Mackall, Patrick Quinn, Martina Markovska, Yingshi Chen, Katherine P Mueller, Alexander E Doan, Andy Chen, Geoffrey Rouin, Bence Daniel, John Lattin, Brett Mozarsky, Jose Arias-Umana, Robert Hapke, Inyoung Jung, Dorota Klysz, Malek Bashti, Wenxi Zhang, Junior Hall, Caleb A Lareau, Elena Sotillo, Ansuman T Satpathy, Evan W Weber
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/217a9a8ee6f74a2fb315bf07253d21ba
Autor:
Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh, Lea Wenting Rysavy, Won-Ju Kim, Caleb Lareau, Elena Sotillo, Evan W. Weber, Skyler P. Rietberg, Guillermo Nicolas Dalton, Yajie Yin, Dorota Klysz, Peng Xu, Eva L. de la Serna, Alexander R. Dunn, Ansuman T. Satpathy, Crystal L. Mackall, Robbie G. Majzner
Publikováno v:
Nature. 615:507-516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89299b7d211d80ffb693266aaf4e3756
https://doi.org/10.1038/s41586-023-05778-2
https://doi.org/10.1038/s41586-023-05778-2
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Patrick J. Quinn, Maria C. Ramello, Meena Malipatlolla, Bence Daniel, Katalin Sandor, Dorota Klysz, Jeremy Bjelajac, Peng Xu, Kylie A. Burdsall, Victor Tieu, Vandon T. Duong, Micah G. Donovan, Evan W. Weber, Howard Y. Chang, Robbie G. Majzner, Joaquin M. Espinosa, Ansuman T. Satpathy, Crystal L. Mackall
Publikováno v:
Science (New York, N.Y.). 378(6620)
T cells are the major arm of the immune system responsible for controlling and regressing cancers. To identify genes limiting T cell function, we conducted genome-wide CRISPR knockout screens in human chimeric antigen receptor (CAR) T cells. Top hits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b83349223e31c0d1c63b5edc787703d
https://pubmed.ncbi.nlm.nih.gov/36356156
https://pubmed.ncbi.nlm.nih.gov/36356156
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Bence Daniel, Katalin Sandor, Dorota Klysz, Vandon T. Duong, Kylie Burdsall, Peng Xu, Meena Malipatlolla, Micah G. Donovan, Evan W. Weber, Robbie G. Majzner, Howard Y. Chang, Joaquin M. Espinosa, Ansuman T. Satpathy, Crystal L. Mackall
Adoptive T cell immune therapies mediate impressive clinical benefit in a fraction of patients, but anti-tumor effects are often limited by inadequate T cell potency. To identify genes limiting T cell effector function, we conducted genome-wide CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c4cb769a4ea3af40b5569af5a8250f
https://doi.org/10.1101/2022.09.02.506235
https://doi.org/10.1101/2022.09.02.506235
Autor:
Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh, Lea Wenting Rysavy, Skyler P. Rietberg, Eva L. de la Serna, Guillermo Nicolas Dalton, Dorota Klysz, Evan W. Weber, Won-Ju Kim, Peng Xu, Elena Sotillo, Alexander R. Dunn, Crystal L. Mackall, Robbie G. Majzner
Introductory paragraphWhile CAR T cells have altered the treatment landscape for B cell malignancies, the risk of on-target, off-tumor toxicity has hampered their development for solid tumors because most target antigens are shared with normal cells1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74e6d8d737eca94d3cb85be7704a6e2
https://doi.org/10.1101/2022.06.17.496457
https://doi.org/10.1101/2022.06.17.496457
Abstract 1158: Inosine endows CAR T cells with features of increased stemness and anti-tumor potency
Autor:
Dorota Klysz, Katie Freitas, Meena Malipatlolla, Stefanie Maier, Carley Fowler, Louai Labanieh, Lucille Stuani, Bence Daniel, Katalin Sandor, Peng Xu, Jing Huang, Amaury Leruste, Vimal Keerthi, Nikolaos Gkitsas, Shabnum Patel, Justin Arredondo-Guerrero, Chris Fisher, Kyle Asano, Sunny Patel, Ansuman Satpathy, Kara Davis, Elena Sotillo, Steven Feldman, Crystal Mackall
Publikováno v:
Cancer Research. 83:1158-1158
Chimeric antigen receptors (CARs) are synthetic receptors that link an extracellular tumor specific domain to intracellular signaling domains. Despite of remarkable results against refractory B cell malignancies, intense effort is underway to augment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a991d4648001aeaef8e313501541603
https://doi.org/10.1158/1538-7445.am2023-1158
https://doi.org/10.1158/1538-7445.am2023-1158
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Bence Daniel, Katalin Sandor, Dorota Klysz, Vandon T. Duong, Peng Xu, Meena Malipatlolla, Evan W. Weber, Robbie G. Majzner, Howard Y. Chang, Ansuman T. Satpathy, Crystal Mackall
Publikováno v:
Cancer Research. 82:2822-2822
Adoptive T cell immune therapies mediate impressive clinical benefit in a fraction of patients, but anti-tumor effects are often limited by inadequate T cell potency. To identify genes that limit T cell effector function, we conducted genome-wide CRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8520697bdbbfbc4d2792c676f26752c6
https://doi.org/10.1158/1538-7445.am2022-2822
https://doi.org/10.1158/1538-7445.am2022-2822
Autor:
Dorota Klysz, Meena Malipatlolla, Katherine Freitas, Malek Bashti, Louai Labanieh, Peng Xu, Cecilia Ramello, Amaury Lerust, Hyatt Balke Want, Kaithlen Zen Pacheco, Evan W. Weber, Shabnum Patel, Steven Feldman, Elena Sotillo, Crystal L. Mackall
Publikováno v:
Cancer Research. 82:1362-1362
Chimeric Antigen Receptor (CAR) T cell therapy has resulted in remarkable clinical outcomes in the context of acute and chronic lymphoblastic leukemia, but remains unsuccessful in the treatment of solid tumors. One reason for this failure is thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518bd51ede7aa0f7662499ca276cb3ac
https://doi.org/10.1158/1538-7445.am2022-1362
https://doi.org/10.1158/1538-7445.am2022-1362
Autor:
Louai Labanieh, Robbie G. Majzner, Dorota Klysz, Elena Sotillo, Chris J. Fisher, José G. Vilches-Moure, Kaithlen Zen B. Pacheco, Meena Malipatlolla, Peng Xu, Jessica H. Hui, Tara Murty, Johanna Theruvath, Nishant Mehta, Sean A. Yamada-Hunter, Evan W. Weber, Sabine Heitzeneder, Kevin R. Parker, Ansuman T. Satpathy, Howard Y. Chang, Michael Z. Lin, Jennifer R. Cochran, Crystal L. Mackall
Publikováno v:
Cell. 185:1745-1763.e22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c55a3713bbd36f19abc22b037ea460f
https://doi.org/10.1016/j.cell.2022.03.041
https://doi.org/10.1016/j.cell.2022.03.041