Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dorota Iwaszkiewicz‐Grześ"'
Autor:
Samikshya Santosh Nirmala, Kayani Kayani, Mateusz Gliwiński, Yueyuan Hu, Dorota Iwaszkiewicz-Grześ, Magdalena Piotrowska-Mieczkowska, Justyna Sakowska, Martyna Tomaszewicz, José Manuel Marín Morales, Kavitha Lakshmi, Natalia Maria Marek-Trzonkowska, Piotr Trzonkowski, Ye Htun Oo, Anke Fuchs
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The initial idea of a distinct group of T-cells responsible for suppressing immune responses was first postulated half a century ago. However, it is only in the last three decades that we have identified what we now term regulatory T-cells (Tregs), a
Externí odkaz:
https://doaj.org/article/ad7a91b69f724da59a68e02fb2a5ce33
Autor:
Juliusz Maksymilian Walczak, Dorota Iwaszkiewicz-Grześ, Michalina Ziomkowska, Magdalena Śliwka-Kaszyńska, Mateusz Daśko, Piotr Trzonkowski, Grzegorz Cholewiński
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2725-2741 (2022)
The group of 18 new amide derivatives of mycophenolic acid (MPA) and selected heterocyclic amines was synthesised as potential immunosuppressive agents functioning as inosine-5′-monophosphate dehydrogenase (IMPDH) uncompetitive inhibitors. The synt
Externí odkaz:
https://doaj.org/article/498254b97d354c888722d7f34919fc29
Autor:
Anna Wołoszyn-Durkiewicz, Dorota Iwaszkiewicz-Grześ, Dominik Świętoń, Mariusz J. Kujawa, Anna Jankowska, Agata Durawa, Paulina Glasner, Piotr Trzonkowski, Leopold Glasner, Edyta Szurowska, Małgorzata Myśliwiec
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1565 (2024)
Type 1 diabetes (T1D) is a progressive disorder leading to the development of microangiopathies and macroangiopathies. Numerous cytokines and chemokines are involved in the pathogenesis of T1D complications. The study aimed to assess the presence of
Externí odkaz:
https://doaj.org/article/47d8192b647347f795b2df447ecf237c
Autor:
Mateusz Gliwiński, Dorota Iwaszkiewicz-Grześ, Anna Wołoszyn-Durkiewicz, Monika Tarnowska, Magdalena Żalińska, Matylda Hennig, Hanna Zielińska, Anna Dukat-Mazurek, Joanna Zielkowska-Dębska, Maciej Zieliński, Anna Jaźwińska-Curyłło, Radosław Owczuk, Przemysława Jarosz-Chobot, Artur Bossowski, Agnieszka Szadkowska, Natalia Marek-Trzonkowska, Grażyna Moszkowska, Janusz Siebert, Małgorzata Myśliwiec, Piotr Trzonkowski
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
ObjectiveHere we looked for possible mechanisms regulating the progression of type 1 diabetes mellitus (T1DM). In this disease, autoaggressive T cells (T conventional cells, Tconvs) not properly controlled by T regulatory cells (Tregs) destroy pancre
Externí odkaz:
https://doaj.org/article/ab4857077c9e42efa4de41884a712ae6
Autor:
Anja Ten Brinke, Natalia Marek-Trzonkowska, Maria J. Mansilla, Annelies W. Turksma, Karolina Piekarska, Dorota Iwaszkiewicz-Grześ, Laura Passerini, Grazia Locafaro, Joan Puñet-Ortiz, S. Marieke van Ham, Maria P. Hernandez-Fuentes, Eva M. Martínez-Cáceres, Silvia Gregori
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/bd0688c4eab749ae97359dca911f1bab
Autor:
Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medi
Externí odkaz:
https://doaj.org/article/6e6307c0ff3e4a65bfd0edfff5a979c4
Autor:
Anja Ten Brinke, Natalia Marek-Trzonkowska, Maria J. Mansilla, Annelies W. Turksma, Karolina Piekarska, Dorota Iwaszkiewicz-Grześ, Laura Passerini, Grazia Locafaro, Joan Puñet-Ortiz, S. Marieke van Ham, Maria P. Hernandez-Fuentes, Eva M. Martínez-Cáceres, Silvia Gregori
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)-presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid
Externí odkaz:
https://doaj.org/article/1481d2a04f874d09b7c28919d3cee808
Autor:
Maciej Zieliński, Magdalena Żalińska, Dorota Iwaszkiewicz‐Grześ, Mateusz Gliwiński, Matylda Hennig, Anna Jaźwińska‐Curyłło, Halla Kamińska, Justyna Sakowska, Anna Wołoszyn‐Durkiewicz, Radosław Owczuk, Wojciech Młynarski, Przemysława Jarosz‐Chobot, Artur Bossowski, Agnieszka Szadkowska, Janusz Siebert, Małgorzata Myśliwiec, Natalia Marek‐Trzonkowska, Piotr Trzonkowski
Publikováno v:
Diabetes, Obesity and Metabolism. 24:1534-1543
Autor:
Małgorzata Grzywińska, Anna Jaźwińska-Curyłło, Kamil Chwojnicki, Paulina Glasner, Marlena Kubach, Maciej Zieliński, Piotr Trzonkowski, Aleksandra Konarzewska, Kamil Kowalczyk, Paweł Łowiec, Walenty M. Nyka, Justyna Sakowska, Dorota Iwaszkiewicz-Grześ, Julia Kulczycka, Anna Jankowska, Bartosz Karaszewski, Edyta Szurowska, Mateusz Gliwiński
Publikováno v:
BioDrugs. 35:47-60
Multiple sclerosis (MS) is an immune-mediated disease in which autoimmune T conventional (Tconv) cells break the blood–brain barrier and destroy neurons of the central nervous system. It is hypothesized that CD4+CD25highCD127−FoxP3+ T regulatory
Autor:
Maciej, Zieliński, Magdalena, Żalińska, Dorota, Iwaszkiewicz-Grześ, Mateusz, Gliwiński, Matylda, Hennig, Anna, Jaźwińska-Curyłło, Halla, Kamińska, Justyna, Sakowska, Anna, Wołoszyn-Durkiewicz, Radosław, Owczuk, Wojciech, Młynarski, Przemysława, Jarosz-Chobot, Artur, Bossowski, Agnieszka, Szadkowska, Janusz, Siebert, Małgorzata, Myśliwiec, Natalia, Marek-Trzonkowska, Piotr, Trzonkowski
Publikováno v:
Diabetes, obesitymetabolismREFERENCES. 24(8)
Monotherapy with autologous expanded CD4We conducted a three-arms clinical trial to explore the efficacy and safety of the combined treatment with Tregs and rituximab in paediatric patients with T1DM. The patients were allocated to three groups: Treg