Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Dorota Gurda-Woźna"'
1
Akademický článek
Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines
Autor: Sebastian Rykowski, Dorota Gurda-Woźna, Agnieszka Fedoruk-Wyszomirska, Marta Orlicka-Płocka, Aleksandra Kowalczyk, Paweł Stączek, Marta Denel-Bobrowska, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Eliza Wyszko, Agnieszka B. Olejniczak
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of 4-carboranyl-3-nitro-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, were synthesi
Externí odkaz: https://doaj.org/article/da14e44f868943c69fa7db724c26232b
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2
Akademický článek
Translation of human Δ133p53 mRNA and its targeting by antisense oligonucleotides complementary to the 5'-terminal region of this mRNA.
Autor: Paulina Żydowicz-Machtel, Mariola Dutkiewicz, Agata Swiatkowska, Dorota Gurda-Woźna, Jerzy Ciesiołka
Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0256938 (2021)
The p53 protein is expressed as at least twelve protein isoforms. Within intron 4 of the human TP53 gene, a P2 transcription initiation site is located and this transcript encodes two p53 isoforms: Δ133p53 and Δ160p53. Here, the secondary structure
Externí odkaz: https://doaj.org/article/58104ef2ee3e40c29e2fdfe9a66fa15d
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3
Akademický článek
Implications of Oxidative Stress in Glioblastoma Multiforme Following Treatment with Purine Derivatives
Autor: Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Dorota Gurda-Woźna, Paweł Pawelczak, Patrycja Krawczyk, Małgorzata Giel-Pietraszuk, Grzegorz Framski, Tomasz Ostrowski, Eliza Wyszko
Publikováno v: Antioxidants, Vol 10, Iss 6, p 950 (2021)
Recently, small compound-based therapies have provided new insights into the treatment of glioblastoma multiforme (GBM) by inducing oxidative impairment. Kinetin riboside (KR) and newly designed derivatives (8-azaKR, 7-deazaKR) selectively affect the
Externí odkaz: https://doaj.org/article/83db956acc3f42ef83ec6d3716681449
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4
Design of DNA Intercalators Based on 4-Carboranyl-1,8-Naphthalimides: Investigation of Their DNA-Binding Ability and Anticancer Activity
Autor: Sebastian Rykowski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Małgorzata Giel-Pietraszuk, Eliza Wyszko, Aleksandra Kowalczyk, Paweł Stączek, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4598
In the present study, we continue our work related to the synthesis of 1,8-naphthalimide and carborane conjugates and the investigation of their anticancer activity and DNA-binding ability. For this purpose, a series of 4-carboranyl-1,8-naphthalimide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f14cbc7daad357a401a53c6b7c1bc47
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5
Implications of Oxidative Stress in Glioblastoma Multiforme Following Treatment with Purine Derivatives
Autor: Grzegorz Framski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Patrycja A. Krawczyk, Małgorzata Giel-Pietraszuk, Tomasz Ostrowski, Eliza Wyszko, Paweł Pawelczak
Publikováno v: Antioxidants, Vol 10, Iss 950, p 950 (2021)
Antioxidants
Volume 10
Issue 6
Recently, small compound-based therapies have provided new insights into the treatment of glioblastoma multiforme (GBM) by inducing oxidative impairment. Kinetin riboside (KR) and newly designed derivatives (8-azaKR, 7-deazaKR) selectively affect the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b7ea2ff51e542cae941d6dc37088f1
https://www.mdpi.com/2076-3921/10/6/950
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6
Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents
Autor: Małgorzata Giel-Pietraszuk, Agnieszka B. Olejniczak, Wojciech Rypniewski, Marta Orlicka-Płocka, Eliza Wyszko, Agnieszka Kiliszek, Agnieszka Fedoruk-Wyszomirska, Andrzej Bak, Dorota Gurda-Woźna, Aleksandra Kowalczyk, Sebastian Rykowski, Paweł Stączek
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2772, p 2772 (2021)
International journal of molecular sciences 22(5), 2772 (2021). doi:10.3390/ijms22052772
International journal of molecular sciences 22(5), 2772 (2021). doi:10.3390/ijms22052772
We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b533d9e3e5b43aaf030b4d91d823aeea
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7
Translation of human Δ133p53 mRNA and its targeting by antisense oligonucleotides complementary to the 5'-terminal region of this mRNA
Autor: Dorota Gurda-Woźna, Paulina Żydowicz-Machtel, Agata Swiatkowska, Jerzy Ciesiołka, Mariola Dutkiewicz
Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0256938 (2021)
PLoS ONE
The p53 protein is expressed as at least twelve protein isoforms. Within intron 4 of the human TP53 gene, a P2 transcription initiation site is located and this transcript encodes two p53 isoforms: Δ133p53 and Δ160p53. Here, the secondary structure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3dc3d7d28b638368935d92cfc90b1b
https://doaj.org/article/58104ef2ee3e40c29e2fdfe9a66fa15d
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