Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Dorota G, Piotrowska"'
Publikováno v:
Farmacja Polska, Vol 79, Iss 12, Pp 789-800 (2024)
Alzheimer’s disease (AD) is a neurodegenerative disorder. Although the first case of Alzheimer’s disease was recorded over a century ago, the etiology of the disease remains unknown. There are several hypotheses regarding the process of neurodege
Externí odkaz:
https://doaj.org/article/452bebf2419e4139a0ae076147cd942a
Autor:
Katarzyna Gawron, Dorota G. Piotrowska, Graciela Andrei, Dominique Schols, Robert Snoeck, Iwona E. Głowacka
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 5, Pp 775-793 (2023)
A new series of N-(diethylphosphonoalkyl)-1,8-naphthalimides were synthesized via direct reaction of 1,8-naphthalic anhydride or its 3-nitro- and 4-bromo- derivatives with selected ɷ-aminoalkylphosphonates and evaluated against a broad-spectrum of v
Externí odkaz:
https://doaj.org/article/a5f9cdde73cf449e91a9bca8ad2a9f15
Autor:
Magdalena Łysakowska, Iwona E. Głowacka, Ewelina Honkisz-Orzechowska, Jadwiga Handzlik, Dorota G. Piotrowska
Publikováno v:
Molecules, Vol 29, Iss 13, p 3050 (2024)
In this study, a new series of cis and trans 5-substituted-3-(dibenzyloxyphosphoryl)isoxazolidines 16a–g were synthesized by the 1,3-dipolar cycloaddition reaction of N-benzyl-C-(dibenzyloxyphosphoryl)nitrone and selected N1-allyl-N3-benzylquinazol
Externí odkaz:
https://doaj.org/article/b6bb75c24596445f9790ed339e54bf83
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5908 (2024)
The synthesis, antioxidant capacity, and anti-inflammatory activity of four novel N-benzyl-2-[4-(aryl)-1H-1,2,3-triazol-1-yl]ethan-1-imine oxides 10a–d are reported herein. The nitrones 10a–d were tested for their antioxidant properties and their
Externí odkaz:
https://doaj.org/article/6cbe12a7bf744e52be41d41d68e43811
Autor:
Katarzyna Niedziałkowska, Aleksandra Felczak, Iwona E. Głowacka, Dorota G. Piotrowska, Katarzyna Lisowska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13722 (2023)
One of the main challenges of medicinal chemistry is the search for new substances with antimicrobial potential that could be used in the fight against pathogenic microorganisms. Therefore, the antimicrobial activity of newly synthesized compounds is
Externí odkaz:
https://doaj.org/article/f41a135b5e1d4aa7997bd93cc1bdc4f6
Publikováno v:
Molecules, Vol 28, Iss 3, p 1466 (2023)
Simple and efficient strategies for the syntheses of enantiomerically enriched functionalized diethyl 2-amino-, 2,3-diamino- and 2-amino-3-hydroxypropylphosphonates have been developed starting from, respectively, N-protected (aziridin-2-yl)methylpho
Externí odkaz:
https://doaj.org/article/006e6ab7e68e41948e5565cf7034a378
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 36 (2022)
Herein, we report the synthesis and antioxidant capacity of twelve novel 1,2,3-triazole-containing nitrones such as N-(2-(4-aryl-1H-1,2,3-triazol-1-yl)ethylidene)methanamine oxides 8a–f and N-(2-(4-aryl)-1H-1,2,3-triazol-1-yl)ethylidene)-2-methylpr
Externí odkaz:
https://doaj.org/article/71b8d4f1c1ed4ac9af48c432f07963cd
Autor:
Izabela Weremczuk-Jeżyna, Katarzyna Hnatuszko-Konka, Liwia Lebelt, Dorota G. Piotrowska, Izabela Grzegorczyk-Karolak
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15147 (2022)
Triacontanol (TRIA) has been reported to influence signal transduction in the crosstalk triggered by various stress factors. As a signal player, it is also known to affect many physiological processes, including enhancing the biosynthesis of secondar
Externí odkaz:
https://doaj.org/article/df0b07245f0c4b16aff03d636f73fdd5
Autor:
Magdalena Łysakowska, Iwona E. Głowacka, Graciela Andrei, Dominique Schols, Robert Snoeck, Paweł Lisiecki, Magdalena Szemraj, Dorota G. Piotrowska
Publikováno v:
Molecules, Vol 27, Iss 19, p 6526 (2022)
Dipolar cycloaddition of the N-substituted C-(diethoxyphosphonyl)nitrones with N3-allyl-N1-benzylquinazoline-2,4-diones produced mixtures of diastereoisomeric 3-(diethoxyphosphonyl)isoxazolidines with a N1-benzylquinazoline-2,4-dione unit at C5. The
Externí odkaz:
https://doaj.org/article/8b6be0e2e6704e748d8d5ae29adf2ad9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1722-1757 (2019)
Since Garner’s aldehyde has several drawbacks, first of all is prone to racemization, alternative three-carbon chirons would be of great value in enantioselective syntheses of natural compounds and/or drugs. This review article summarizes applicati
Externí odkaz:
https://doaj.org/article/e3f96b7f57b44000abda0281f4c8d9c3