Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Doron Ginsberg"'
Autor:
Yulia Haim, Matthias Blüher, Daniel Konrad, Nir Goldstein, Nora Klöting, Ilana Harman-Boehm, Boris Kirshtein, Doron Ginsberg, Tanya Tarnovscki, Yftach Gepner, Iris Shai, Assaf Rudich
Publikováno v:
Molecular Metabolism, Vol 6, Iss 7, Pp 725-736 (2017)
Objective: Obesity variably disrupts human health, but molecular-based patients' health-risk stratification is limited. Adipose tissue (AT) stresses may link obesity with metabolic dysfunction, but how they signal in humans remains poorly-characteriz
Externí odkaz:
https://doaj.org/article/a6e72e1ef48b40659e43d1e99c48e107
Autor:
Shahinaz Mahajna, Sleman Kadan, Zipora Tietel, Bashar Saad, Said Khasib, Aziz Tumeh, Doron Ginsberg, Hilal Zaid
Publikováno v:
Molecules, Vol 24, Iss 22, p 4139 (2019)
Naturally derived drugs and plant-based products are attractive commodities that are being explored for cancer treatment. This in vitro study aimed to investigate the role of Hypericum triquetrifolium (50% ethanol: 50% water) extract (HTE) treatment
Externí odkaz:
https://doaj.org/article/c33eb4a001b14370ba657f3e7a8e853a
Autor:
Inbal Gazy, David A Zeevi, Paul Renbaum, Sharon Zeligson, Lital Eini, Dana Bashari, Yoav Smith, Amnon Lahad, Michal Goldberg, Doron Ginsberg, Ephrat Levy-Lahad
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134120 (2015)
Expression of RAD51, a crucial player in homologous recombination (HR) and DNA double-strand break (DSB) repair, is dysregulated in human tumors, and can contribute to genomic instability and tumor progression. To further understand RAD51 regulation
Externí odkaz:
https://doaj.org/article/6f1ab59491a44b51971a3152e973f86d
Autor:
Sharon Noy-Lotan, Orly Dgany, Roxane Lahmi, Nathaly Marcoux, Tanya Krasnov, Nissan Yissachar, Doron Ginsberg, Benny Motro, Peretz Resnitzky, Isaac Yaniv, Gary M. Kupfer, Hannah Tamary
Publikováno v:
Haematologica, Vol 94, Iss 5 (2009)
Background Congenital dyserythropoietic anemia type I is an inherited autosomal recessive macrocytic anemia associated with ineffective erythropoiesis and the development of secondary hemochromatosis. Distinct erythroid precursors with internuclear c
Externí odkaz:
https://doaj.org/article/53d77ab182cb4ac887fb5899e36c705e
Supplementary Data from The Tumor Suppressor Maspin Mediates E2F1-Induced Sensitivity of Cancer Cells to Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642fe03fd96c0293617dafccc140b125
https://doi.org/10.1158/1541-7786.22518651
https://doi.org/10.1158/1541-7786.22518651
PDF file - 94K, Activation of ectopic E2F1 upregulates RBM38 expression in a p53-independent manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b2ac3569726260f642ca167c7556d4
https://doi.org/10.1158/1541-7786.22516675
https://doi.org/10.1158/1541-7786.22516675
Supplementary Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4429da5ba95be5f879cb7f41415cfe0f
https://doi.org/10.1158/1541-7786.22518853
https://doi.org/10.1158/1541-7786.22518853
The E2F family of transcription factors plays a pivotal role in the regulation of cell proliferation in higher eukaryotes and is a critical downstream target of the tumor suppressor pRB. The pRB/E2F pathway is defective in most human tumors, resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb14c2fed0e71110664b2b511d6079e
https://doi.org/10.1158/1541-7786.c.6541441.v1
https://doi.org/10.1158/1541-7786.c.6541441.v1
The E2F1 transcription factor is a critical downstream target of the tumor suppressor RB. When activated, E2F1 can induce cell proliferation and/or apoptosis. In addition, E2F1 overexpression sensitizes cancer cells to chemotherapeutic drugs. In a sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6734878eaeaa9a68a2f665d7fd4473b7
https://doi.org/10.1158/1541-7786.c.6542046.v1
https://doi.org/10.1158/1541-7786.c.6542046.v1
PDF file - 171K, Activation of ectopic E2F1or endogenous E2F1 silencing regulates RBM38 levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dce6dbe5310fc21af273df2c36b6c16
https://doi.org/10.1158/1541-7786.22516678
https://doi.org/10.1158/1541-7786.22516678