Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Dornadula Sireesh"'
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 10, Iss 8, Pp 379-386 (2020)
Objective: To investigate the effects of Gymnema montanum leaf extract against endoplasmic reticulum (ER) stress-induced toxicity in endothelial cells. Methods: The immortalized endothelial hybrid cell, EA.hy926 was treated with different concentrati
Externí odkaz:
https://doaj.org/article/85ca84d0dc6340b8afdc7e18497a5156
Autor:
Rashmi Rajappa, Dornadula Sireesh, Magesh B. Salai, Kunka M. Ramkumar, Suryanarayanan Sarvajayakesavulu, SubbaRao V. Madhunapantula
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
Chronic hyperglycemia and unusually high oxidative stress are the key contributors for diabetes in humans. Since nuclear factor E2-related factor 2 (Nrf2) controls the expression of antioxidant- and detoxification genes, it is hypothesized that targe
Externí odkaz:
https://doaj.org/article/319523194fe14e3ebc8e7d0eff560cd7
Autor:
Umapathy, Dhamodharan, Dornadula, Sireesh, Krishnamoorthy, Ezhilarasi, Mariappanadar, Vairamani, Viswanathan, Vijay, Ramkumar, Kunka Mohanram
Publikováno v:
In Immunobiology November 2018 223(11):718-727
Autor:
Arumugam Somasundar, Dornadula Sireesh, Kesavan Rajesh, Alladi Vaishnavi, Amin Karan, Kunka Mohanram Ramkumar, Umapathy Dhamodharan
Publikováno v:
Free Radical Biology and Medicine. 138:53-62
Hyperbaric oxygen (HBO) therapy is proven to be very successful for diabetic foot ulcer (DFU) treatment due to its antimicrobial effect, increased angiogenesis and enhanced collagen synthesis. The molecular mechanism underlying HBO therapy particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf2d9d7d0cb71ac4b806309a0255f61
https://doi.org/10.1016/j.freeradbiomed.2019.04.031
https://doi.org/10.1016/j.freeradbiomed.2019.04.031
Akademický článek
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Publikováno v:
Pharmacological Research. 119:412-421
ER stress is provoked by the accumulation of unfolded and misfolded proteins in the ER lumen leading to perturbations in ER homeostasis. ER stress activates a signaling cascade called the Unfolded Protein Response (UPR) which triggers a set of transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e727bf57d4eaf01f9a15737b80695bd
https://doi.org/10.1016/j.phrs.2017.02.018
https://doi.org/10.1016/j.phrs.2017.02.018
Autor:
Kunka Mohanram Ramkumar, Dornadula Sireesh, Palani Gunasekaran, Srinivasan Sivasubramanian, Murugesan Sakthivadivel, Elango Bhakkiyalakshmi
Publikováno v:
European Journal of Pharmacology. 777:9-16
Nuclear factor erythroid 2-related factor (Nrf2), a key transcription factor triggers the expression of antioxidant and detoxification genes thereby providing cellular protective functions against oxidative stress-mediated disorders. Recent research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597c5d18398d236f9e9a412d00ea332b
https://doi.org/10.1016/j.ejphar.2016.02.054
https://doi.org/10.1016/j.ejphar.2016.02.054
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 10, Iss 8, Pp 379-386 (2020)
Objective: To investigate the effects of Gymnema montanum leaf extract against endoplasmic reticulum (ER) stress-induced toxicity in endothelial cells. Methods: The immortalized endothelial hybrid cell, EA.hy926 was treated with different concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad83d3b378cd8c2c02111b6d2431bac
https://doi.org/10.4103/2221-1691.287164
https://doi.org/10.4103/2221-1691.287164
Autor:
Rashmi, Rajappa, Dornadula, Sireesh, Magesh B, Salai, Kunka M, Ramkumar, Suryanarayanan, Sarvajayakesavulu, SubbaRao V, Madhunapantula
Publikováno v:
Frontiers in Pharmacology
Chronic hyperglycemia and unusually high oxidative stress are the key contributors for diabetes in humans. Since nuclear factor E2-related factor 2 (Nrf2) controls the expression of antioxidant- and detoxification genes, it is hypothesized that targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc8fcc3f3e5fb2201a6ca2394f478322
https://pubmed.ncbi.nlm.nih.gov/30745874
https://pubmed.ncbi.nlm.nih.gov/30745874
Autor:
Umapathy Dhamodharan, Kunka Mohanram Ramkumar, Elango Bhakkiyalakshmi, Balashanmugam Ponjayanthi, Dornadula Sireesh
Publikováno v:
Pharmacological research. 137
Keap1, Kelch-like erythroid derived Cap ‘n’ collar homology (ECH) associated protein 1 is a highly redox-sensitive member of the BTB-Kelch substrate adaptor protein which acts as a major upstream regulator of Nrf2 (Nuclear factor erythroid 2-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ab26924b5146de8f89342a19b201ea
https://pubmed.ncbi.nlm.nih.gov/30296569
https://pubmed.ncbi.nlm.nih.gov/30296569