Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dorna Ravamehr-Lake"'
Autor:
Mathias Schenkel, Dorna Ravamehr-Lake, Tomasz Czerniak, James P. Saenz, Georg Krainer, Michael Schlierf, Charles M. Deber
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1865:184078
Cystic fibrosis (CF) is caused by mutations in the gene that codes for the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR). Recent advances in CF treatment have included use of small-molecule drugs known as modulators, suc
Autor:
Dorna Ravamehr-Lake, Richard James, Howard Leong-Poi, Mavra Ahmed, Abdul Al-Hesayen, Shirley Quach, Eduardo R. Azevedo, Andrew T. Yan, Mary Keith, Sarah Desjardins, Parastoo Azizi-Namini, P.J. Lee, Geraldine Ong
Publikováno v:
The American Journal of Clinical Nutrition. 110:1287-1295
BACKGROUND Thiamin, a water-soluble B-complex vitamin, functions as a coenzyme in macronutrient oxidation and in the production of cellular ATP. Data suggest that thiamin depletion occurs in heart failure (HF). Therefore, thiamin supplementation in H
Autor:
Tracy A. Stone, Farheen Khan, Huong Q. Nguyen, Simon Sharpe, Dorna Ravamehr-Lake, Charles M. Deber, Gregory B. Cole
Publikováno v:
Journal of medicinal chemistry. 62(13)
Natural α-helical cationic antimicrobial peptide (CAP) sequences are predominantly amphipathic, with only ca. 2% containing four or more consecutive positively charged amino acids (Lys/Arg). We have designed synthetic CAPs that deviate from these na