Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dorna Kashef-Haghighi"'
Autor:
Jin Xu, Chanpreet Singh, Kelley Paskov, Olivia Leventhal, Jae-Yoon Jung, Christopher Hartl, Damon Polioudakis, Lee-kai Wang, Virpi Leppa, David A. Prober, Michael J. Gandal, Elizabeth K. Ruzzo, Dennis P. Wall, Daniel H. Geschwind, Jennifer K. Lowe, Jackson N Hoekstra, Dorna Kashef-Haghighi, Nate Tyler Stockham, Laura Pérez-Cano
Publikováno v:
Cell
Cell, vol 178, iss 4
Cell, vol 178, iss 4
We performed a comprehensive assessment of rare inherited variation in autism spectrum disorder (ASD) by analyzing whole-genome sequences of 2,308 individuals from families with multiple affected children. We implicate 69 genes in ASD risk, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10032f4781afc8e4e361eb6ad6c4083
https://resolver.caltech.edu/CaltechAUTHORS:20190808-135241284
https://resolver.caltech.edu/CaltechAUTHORS:20190808-135241284
Autor:
Michael J. Gandal, Nate Tyler Stockham, Olivia Leventhal, Daniel H. Geschwind, Elizabeth K. Ruzzo, Damon Polioudakis, Christopher Hartl, Jennifer K. Lowe, Jae-Yoon Jung, Jackson N Hoekstra, Kelley Paskov, Dennis P. Wall, Laura Pérez-Cano, Dorna Kashef-Haghighi, Lee-kai Wang
Genetic studies of autism spectrum disorder (ASD) have revealed a complex, heterogeneous architecture, in which the contribution of rare inherited variation remains relatively un-explored. We performed whole-genome sequencing (WGS) in 2,308 individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d059bf97ae266c82dd4545f16bb2b9
Autor:
Jae-Yoon Jung, Lee-kai Wang, Daniel H. Geschwind, Dorna Kashef-Haghighi, Elizabeth K. Ruzzo, Christopher Hartl, David A. Prober, Jennifer K. Lowe, Laura Pérez-Cano, Dennis P. Wall
Publikováno v:
European Neuropsychopharmacology. 29:S35-S36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0722e0e33ccaf3f9443fdba77b92ef02
https://doi.org/10.1016/j.euroneuro.2019.07.072
https://doi.org/10.1016/j.euroneuro.2019.07.072
Autor:
Z Weng, Robert B. West, Daniel E. Newburger, X Guo, Megan L. Troxell, Dorna Kashef-Haghighi, Serafim Batzoglou, Shirley Zhu, Raheleh Salari, Arend Sidow, Sushama Varma, Alayne L. Brunner
Publikováno v:
Cancer Research. 72:PD05-09
Cancer evolution involves cycles of genomic damage, epigenetic deregulation, and increased cellular proliferation that eventually culminate in the carcinoma phenotype. Early breast neoplasias include usual ductal hyperplasia, columnar cell lesions, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3195b14af1ded9d07ff1c75f39447f9d
https://doi.org/10.1158/0008-5472.sabcs12-pd05-09
https://doi.org/10.1158/0008-5472.sabcs12-pd05-09
Publikováno v:
PSB
Autism has been shown to have a major genetic risk component; the architecture of documented autism in families has been over and again shown to be passed down for generations. While inherited risk plays an important role in the autistic nature of ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dca0e1ab2113a0303d25782f30da58
https://doi.org/10.1142/9789813207813_0048
https://doi.org/10.1142/9789813207813_0048
Autor:
Serafim Batzoglou, Arend Sidow, Shirley Zhu, Robert B. West, Daniel E. Newburger, Dorna Kashef-Haghighi, Noah Spies, Ziming Weng
Publikováno v:
Genome Medicine
Background All cells in an individual are related to one another by a bifurcating lineage tree, in which each node is an ancestral cell that divided into two, each branch connects two nodes, and the root is the zygote. When a somatic mutation occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7453ee50c88a243c8da6b1595cca51a
https://doi.org/10.1186/s13073-015-0146-2
https://doi.org/10.1186/s13073-015-0146-2
Autor:
Alex Bishara, Dorna Kashef-Haghighi, Arend Sidow, Ziming Weng, Yuling Liu, Daniel E. Newburger, Robert B. West, Serafim Batzoglou
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783319167053
RECOMB
RECOMB
Although an increasing amount of human genetic variation is being identified and recorded, determining variants within repeated sequences of the human genome remains a challenge. Most population and genome-wide association studies have therefore been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd97df2f6e5fc6d3d03fbebd52cfa43a
https://doi.org/10.1007/978-3-319-16706-0_5
https://doi.org/10.1007/978-3-319-16706-0_5
Autor:
Dorna Kashef-Haghighi, Raheleh Salari, Alayne L. Brunner, Shirley Zhu, Xiangqian Guo, Daniel E. Newburger, Robert T. Sweeney, Arend Sidow, Sushama Varma, Megan L. Troxell, Robert B. West, Serafim Batzoglou, Ziming Weng
Cancer evolution involves cycles of genomic damage, epigenetic deregulation, and increased cellular proliferation that eventually culminate in the carcinoma phenotype. Early neoplasias, which are often found concurrently with carcinomas and are histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d01811f87c96c7756f639321d4fd5c8
https://europepmc.org/articles/PMC3698503/
https://europepmc.org/articles/PMC3698503/
Autor:
Arend Sidow, Syed Shayon Saleh, David A. Khavari, Serafim Batzoglou, Robert B. West, Daniel E. Newburger, Dorna Kashef-Haghighi, Raheleh Salari
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783642371943
RECOMB
RECOMB
Next-generation sequencing technologies provide a powerful tool for studying genome evolution during progression of advanced diseases such as cancer. Although many recent studies have employed new sequencing technologies to detect mutations across mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d4d7e97b520492e301209ac02c4193
https://doi.org/10.1007/978-3-642-37195-0_21
https://doi.org/10.1007/978-3-642-37195-0_21