Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dorival Mendes Rodrigues-Junior"'
Publikováno v:
Upsala Journal of Medical Sciences, Vol 129, Pp 1-13 (2024)
Deeper analysis of molecular mechanisms arising in tumor cells is an unmet need to provide new diagnostic and therapeutic strategies to prevent and treat tumors. The transforming growth factor β (TGF-β) signaling has been steadily featured in tumor
Externí odkaz:
https://doaj.org/article/2e8f7e25ff254a93b9f209e2bf6fd729
Autor:
Dorival Mendes Rodrigues-Junior, Cristiano Raminelli, Haifa Hassanie, Gustavo Henrique Goulart Trossini, Givago Prado Perecim, Laia Caja, Aristidis Moustakas, André Luiz Vettore
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Glioblastoma (GBM) is the most aggressive and common primary malignant brain tumor with limited available therapeutic approaches. Despite improvements in therapeutic options for GBM patients, efforts to develop new successful strategies rema
Externí odkaz:
https://doaj.org/article/e72ebfa3a7d84b5d9eed23c3df017774
Autor:
Maria Peleli, Ivi Antoniadou, Dorival Mendes Rodrigues-Junior, Odysseia Savvoulidou, Laia Caja, Antonia Katsouda, Daniel F.J. Ketelhuth, Jane Stubbe, Kirsten Madsen, Aristidis Moustakas, Andreas Papapetropoulos
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102773- (2023)
Purpose: Glioblastoma (GBM) is the most common type of adult brain tumor with extremely poor survival. Cystathionine-gamma lyase (CTH) is one of the main Hydrogen Sulfide (H2S) producing enzymes and its expression contributes to tumorigenesis and ang
Externí odkaz:
https://doaj.org/article/485e002a5ab6460d80e4a96c7586eae4
Autor:
Mariana Teixeira Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira, Dorival Mendes Rodrigues-Junior, Mirian Galliote Morale, Joel Machado Júnior, Karina Ramalho Bortoluci, Rodrigo Esaki Tamura, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Eric Chau, Biana Godin, Jamile Calil-Silveira, Ileana G. Sanchez Rubio
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1687 (2023)
Anaplastic thyroid cancer (ATC) is an aggressive form of thyroid cancer (TC), accounting for 50% of total TC-related deaths. Although therapeutic approaches against TC have improved in recent years, the survival rate remains low, and severe adverse e
Externí odkaz:
https://doaj.org/article/a71652dc442f4d3a9f88edb218ec1cd7
Autor:
Luiza Zainotti Miguel Fahur Bottino, Dorival Mendes Rodrigues-Junior, Ingrid Sancho de Farias, Laura Migliari Branco, N. Gopalakrishna Iyer, Gabriela Estrela de Albuquerque, André Luiz Vettore, Karina Ramalho Bortoluci
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 175-183 (2021)
The content of tumor-derived extracellular vesicles (EVs) can regulate the tumor microenvironment and functionally acts in favor of cancer aggressiveness. To better elucidate the role of EVs in the interplay between immune system and tumor microenvir
Externí odkaz:
https://doaj.org/article/1b730a4945f9407f8a40a7d852131a62
Autor:
Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Sai Kiang Lim, Carl-Henrik Heldin, Aristidis Moustakas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Complexity in mechanisms that drive cancer development and progression is exemplified by the transforming growth factor β (TGF-β) signaling pathway, which suppresses early-stage hyperplasia, yet assists aggressive tumors to achieve metastasis. Of n
Externí odkaz:
https://doaj.org/article/a7241c1a9add4497b168bef0c6015ff2
Autor:
Dorival Mendes Rodrigues-Junior, Soon Sim Tan, Luciano de Souza Viana, Andre Lopes Carvalho, Sai Kiang Lim, N Gopalakrishna Iyer, Andre Luiz Vettore
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background There is a paucity of plasma-based biomarkers that prospectively segregate the outcome of patients with head and neck squamous-cell carcinoma (HNSCC) treated with chemoradiation therapy (CRT). Plasma extracellular vesicles (EVs) m
Externí odkaz:
https://doaj.org/article/5d32e3a8679746c6b10951267728026c
Autor:
Gabriela Estrela de Albuquerque, André Luiz Vettore, Laura Migliari Branco, Ingrid Sancho de Farias, Dorival Mendes Rodrigues-Junior, Karina R. Bortoluci, Luiza Zainotti Miguel Fahur Bottino, N. Gopalakrishna Iyer
Publikováno v:
Current Research in Immunology, Vol 2, Iss, Pp 175-183 (2021)
The content of tumor-derived extracellular vesicles (EVs) can regulate the tumor microenvironment and functionally acts in favor of cancer aggressiveness. To better elucidate the role of EVs in the interplay between immune system and tumor microenvir
Autor:
Peter ten Dijke, Maria Catalina Gomez-Puerto, Aristidis Moustakas, Anna Taylor Webb, Carl-Henrik Heldin, Dorival Mendes Rodrigues-Junior, Sijia Liu, Artur Mezheyeuski, Laia Caja, Mahsa Shahidi Dadras
Publikováno v:
Journal of Cellular Physiology, 237(1), 743-762. WILEY
The role of liver kinase B1 (LKB1) in glioblastoma (GBM) development remains poorly understood. LKB1 may regulate GBM cell metabolism and has been suggested to promote glioma invasiveness. After analyzing LKB1 expression in GBM patient mRNA databases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b549d4741f1bbf2ee15c0f979ccb00bb
https://hdl.handle.net/1887/3249671
https://hdl.handle.net/1887/3249671
Autor:
Maria Fernanda de Andrade Pelarin, Dorival Mendes Rodrigues-Junior, Helena B. Nader, Maria Aparecida da Silva Pinhal, André Luiz Vettore
Publikováno v:
OncoTargets and therapy
Dorival Mendes Rodrigues-Junior,1,2 Maria Fernanda de Andrade Pelarin,1 Helena Bonciani Nader,1 André Luiz Vettore,3 Maria Aparecida Silva Pinhal1,4 1Department of Biochemistry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil; 2Inst