Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dorit K. Nägler"'
Autor:
Marlene Tacke, Thomas Reinheckel, Christian P. Sommerhoff, Marianne Jochum, Simon F. Schuster, Steffen Kraus, Dorit K. Nägler, Thea Bunsen, Monika A. Cichoń
Publikováno v:
European Journal of Cell Biology. 90:678-686
Cellular senescence represents a powerful tumor suppressor mechanism to prevent proliferation and invasion of malignant cells. Since tumor cells as well as primary fibroblasts lacking the lysosomal cysteine-type carboxypeptidase cathepsin X exhibit a
Autor:
Dorit K. Nägler, Jens Feierler, Alexander Faussner, Friedrich Lottspeich, Steffen Kraus, Marianne Jochum, Reinhard Mentele
Publikováno v:
International Immunopharmacology. 10:134-139
The kallikrein-kinin system and the renin-angiotensin system interact at different levels and are linked by various molecules such as angiotensin-converting enzyme which degrades bradykinin into inactive peptides. Here we report that a cysteine-type
Autor:
Marianne Jochum, Elisabeth Schremmer-Danninger, Michael J. Flaig, Alexander Faussner, Edwin Fink, Joachim Rehbock, Matthias C. Raggi, Dorit K. Nägler, Kerstin Miska
Publikováno v:
International Immunopharmacology. 7:103-112
Bradykinin and its kinin B(2) receptor are autocrine and paracrine mediators in foetal membranes and decidua. As a first step we characterized the intracellular morphology of decidual cells. Cultured decidua tissue-derived cells immunolabel for vimen
Autor:
Lars Björck, Dorit K. Nägler, Per Åkesson, Matthias Mörgelin, Inga-Maria Frick, Martin Malmsten, Heiko Herwald
Publikováno v:
The EMBO Journal. 25:5569-5578
Activation of the contact system has two classical consequences: initiation of the intrinsic pathway of coagulation, and cleavage of high molecular weight kininogen (HK) leading to the release of bradykinin, a potent proinflammatory peptide. In human
Autor:
Heinz-Peter Scheuber, Annette M. Lechner, Karolina Kozaczynska, Dorit K. Nägler, Peter Biberthaler, Marianne Jochum, Viktoria Bogner, Cornelia Gippner-Steppert, Annemarie Oettl
Publikováno v:
Journal of Immunological Methods. 308:241-250
The human lysosomal cysteine-type carboxypeptidase cathepsin X is mainly present in monocytes and macrophages and may be released into the circulation due to constitutive and/or regulated secretion by (activated) immune cells. To define its potential
Autor:
Robert Ménard, Sabine Krüger, Udo Kellner, Peter Buhtz, Angela Kellner, Albert Roessner, Edmund Ziomek, Dorit K. Nägler, Matthias Krams
Publikováno v:
The Prostate. 60:109-119
BACKGROUND Evidence is accumulating that several proteases are involved in prostate cancer progression. A locus which is often amplified in prostate cancer is the chromosomal region 20q13. Interestingly, one of the genes encoding the cysteine proteas
Publikováno v:
Biochemical and Biophysical Research Communications. 257:313-318
A novel human cDNA encoding a cysteine protease of the papain family named cathepsin F is reported. The mature part of the predicted protease precursor displays between 26% and 42% identity to other human cysteine proteases while the proregion is uni
Autor:
Dorit K. Nägler, Robert Ménard
Publikováno v:
FEBS Letters. 434:135-139
A novel cDNA encoding a cysteine protease of the papain family named cathepsin X was obtained by PCR amplification from a human ovary cDNA library. The cathepsin X cDNA is ubiquitously expressed in human tissues and contains an open reading frame of
Autor:
Dorit K. Nägler, Euridice Carmona, Luiz Juliano, Andrew C. Storer, Fernanda C. V. Portaro, Robert Ménard
Publikováno v:
Biochemistry. 36:12608-12615
The main feature distinguishing cathepsin B from other cysteine proteases of the papain family is the presence of a large insertion loop, termed the occluding loop, which occupies the S' subsites of the enzyme. The loop is held in place mainly by two
The third edition of the Handbook of Proteolytic Enzymes aims to be a comprehensive reference work for the enzymes that cleave proteins and peptides, and contains over 800 chapters. Each chapter is organized into sections describing the name and hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3189a766f5e03dae9e71822a0ae3eb
https://doi.org/10.1016/b978-0-12-382219-2.00415-4
https://doi.org/10.1016/b978-0-12-382219-2.00415-4