Výsledky vyhledávání - "Doris Wedlich"

Akademický článek

Autor: Veronika Wallkamm, Rene Dörlich, Karolin Rahm, Tina Klessing, Gerd Ulrich Nienhaus, Doris Wedlich, Dietmar Gradl

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109428 (2014)

Secreted molecules of the Wnt family regulate key decisions in embryogenesis and adult tissue homeostasis by activating a complex network of Wnt signaling pathways. Although the different branches of Wnt signaling have been studied for more than 25 y

Externí odkaz: https://doaj.org/article/66dcfefdf07041948622c15f65a2821d

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Akademický článek

Covalent and density-controlled surface immobilization of E-cadherin for adhesion force spectroscopy.

Autor: Dagmar Fichtner, Bärbel Lorenz, Sinem Engin, Christina Deichmann, Marieelen Oelkers, Andreas Janshoff, Andre Menke, Doris Wedlich, Clemens M Franz

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e93123 (2014)

E-cadherin is a key cell-cell adhesion molecule but the impact of receptor density and the precise contribution of individual cadherin ectodomains in promoting cell adhesion are only incompletely understood. Investigating these mechanisms would benef

Externí odkaz: https://doaj.org/article/a9e690b24e264888a877593bef385e71

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Akademický článek

PCR-Based RNA Probes: A Quick and Sensitive Method to Improve Whole Mount Embryo In Situ Hybridizations

Autor: Robert David, Doris Wedlich

Publikováno v: BioTechniques, Vol 30, Iss 4, Pp 768-774 (2001)

We have developed a PCR-based technique for the preparation of RNA probes that can be used for whole mount in situ hybridization on embryos. T3 or T7 RNA polymerase promoters were introduced at the 5′ end of gene-specific oligonucleotide primers en

Externí odkaz: https://doaj.org/article/b96acf25d6134a89a64b5b34edb381da

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Akademický článek

Cell differentiation of pluripotent tissue sheets immobilized on supported membranes displaying cadherin-11.

Autor: Alexander Körner, Christina Deichmann, Fernanda F Rossetti, Almut Köhler, Oleg V Konovalov, Doris Wedlich, Motomu Tanaka

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e54749 (2013)

Investigating cohesive tissue sheets in controlled cultures still poses a challenge since the complex intercellular interactions are difficult to mimic in in vitro models. We used supported lipid membranes functionalized by the adhesive part of the e

Externí odkaz: https://doaj.org/article/f34af24a65a94323b2eb4c0e800be332

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Akademický článek

Tension monitoring during epithelial-to-mesenchymal transition links the switch of phenotype to expression of moesin and cadherins in NMuMG cells.

Autor: David Schneider, Thilo Baronsky, Anna Pietuch, Jan Rother, Marieelen Oelkers, Dagmar Fichtner, Doris Wedlich, Andreas Janshoff

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e80068 (2013)

Structural alterations during epithelial-to-mesenchymal transition (EMT) pose a substantial challenge to the mechanical response of cells and are supposed to be key parameters for an increased malignancy during metastasis. Herein, we report that duri

Externí odkaz: https://doaj.org/article/5972bee3b8664a94a3a52eee0223c67d

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