Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Doris Shim"'
Autor:
Malcolm R Starkey, Richard Y Kim, Emma L Beckett, Heidi C Schilter, Doris Shim, Ama-Tawiah Essilfie, Duc H Nguyen, Kenneth W Beagley, Joerg Mattes, Charles R Mackay, Jay C Horvat, Philip M Hansbro
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42588 (2012)
BACKGROUND: Viral and bacterial respiratory tract infections in early-life are linked to the development of allergic airway inflammation and asthma. However, the mechanisms involved are not well understood. We have previously shown that neonatal and
Externí odkaz:
https://doaj.org/article/bdcea32bb868477696ff5bfab351d106
Autor:
Danyal Butt, Jacquelyn Lyons, Matthew Pollard, Anthony Gerard Doyle, Chen Tian, Doris Shim, Jean Husten, David Mabon, Lynn Dorothy Poulton, Adam Clarke, Vanya Pande
Publikováno v:
mAbs
TL1A is an attractive therapeutic target for the treatment of mucosal inflammation associated with inflammatory bowel disease (IBD) and asthma. Blockade of the TL1A pathway has been shown to reduce inflammatory responses while leaving baseline immuni
Autor:
Charles R. Mackay, Angélica T. Vieira, Doris Shim, Maria Cecilia Campos Canesso, Jacquie L. Harper, Laurence Macia, Jacques Robert Nicoli, Cristiana C. Garcia, Flaviano S. Martins, Flávio A. Amaral, Izabela Galvão, Kendle M. Maslowski, Ellen De Leon, Mauro M. Teixeira
Publikováno v:
Arthritis & Rheumatology. 67:1646-1656
Objective Host–microbial interactions are central in health and disease. Monosodium urate monohydrate (MSU) crystals cause gout by activating the NLRP3 inflammasome, leading to interleukin-1β (IL-1β) production and neutrophil recruitment. This st
Autor:
Karolina Windloch, Matilda Lindgren, Chen Tian, Lynn Dorothy Poulton, Beau Corazon, Teresa Domagala, David Mabon, Jonathan Kannan Nambiar, Adam Clarke, Matthew Pollard, Chris Buhmann, Anthony Gerard Doyle, Doris Shim
Publikováno v:
mAbs
CD1d is a receptor on antigen-presenting cells involved in triggering cell populations, particularly natural killer T (NKT) cells, to release high levels of cytokines. NKT cells are implicated in asthma pathology and blockade of the CD1d/NKT cell pat
Autor:
Charles R. Mackay, Heidi Schilter, Philip M. Hansbro, Joerg Mattes, Doris Shim, Jay C. Horvat, Emma L. Beckett, Ama-Tawiah Essilfie, Duc H. Nguyen, Richard Kim, Malcolm R. Starkey, Kenneth W. Beagley
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42588 (2012)
PLoS ONE
PLoS ONE
Background: Viral and bacterial respiratory tract infections in early-life are linked to the development of allergic airway inflammation and asthma. However, the mechanisms involved are not well understood. We have previously shown that neonatal and