Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Doris Popovic"'
Autor:
Chaoran Chen, Sarah Ann Nadeau, Ivan Topolsky, Marc Manceau, Jana S. Huisman, Kim Philipp Jablonski, Lara Fuhrmann, David Dreifuss, Katharina Jahn, Christiane Beckmann, Maurice Redondo, Christoph Noppen, Lorenz Risch, Martin Risch, Nadia Wohlwend, Sinem Kas, Thomas Bodmer, Tim Roloff, Madlen Stange, Adrian Egli, Isabella Eckerle, Laurent Kaiser, Rebecca Denes, Mirjam Feldkamp, Ina Nissen, Natascha Santacroce, Elodie Burcklen, Catharine Aquino, Andreia Cabral de Gouvea, Maria Domenica Moccia, Simon Grüter, Timothy Sykes, Lennart Opitz, Griffin White, Laura Neff, Doris Popovic, Andrea Patrignani, Jay Tracy, Ralph Schlapbach, Emmanouil T. Dermitzakis, Keith Harshman, Ioannis Xenarios, Henri Pegeot, Lorenzo Cerutti, Deborah Penet, Anthony Blin, Melyssa Elies, Christian L. Althaus, Christian Beisel, Niko Beerenwinkel, Martin Ackermann, Tanja Stadler
Publikováno v:
Epidemics, Vol 37, Iss , Pp 100480- (2021)
Background: In December 2020, the United Kingdom (UK) reported a SARS-CoV-2 Variant of Concern (VoC) which is now named B.1.1.7. Based on initial data from the UK and later data from other countries, this variant was estimated to have a transmission
Externí odkaz:
https://doaj.org/article/bd41319829ad4201b8f18a7bf5efe47f
Autor:
David G. McEwan, Georg Tascher, Doris Popovic, Andrea Gubas, Daniela S. Krause, Nina Dawe, Marina E. Hoffmann, Ivan Dikic, Christina Karantanou, Anna Platzek
Publikováno v:
FEBS Letters. 595:864-880
The lysosome is a cellular signalling hub at the point of convergence of endocytic and autophagic pathways, where the contents are degraded and recycled. Pleckstrin homology domain-containing family member 1 (PLEKHM1) acts as an adaptor to facilitate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a168cc4eafd3135eb33c25337057230
https://doi.org/10.1002/1873-3468.14041
https://doi.org/10.1002/1873-3468.14041
Autor:
Ryo Okuda, Bruno Gjeta, Doris Popovic, Ashley Maynard, Qianhui Yu, Zhisong He, Malgorzata Santel, Makiko Seimiya, Soichiro Morinaga, Yohei Miyagi, Tomoyuki Yamaguchi, Yasuharu Ueno, Hideki Taniguichi, Barbara Treutlein, J. Gray Camp
Interlineage communication within a cancer microenvironment can augment cancer cell behaviour and impact response to therapy. Patient-derived cancer organoids provide an opportunity to explore cancer cell biology, however it is a major challenge to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253772512c6f592ad471a7754b8d85eb
https://doi.org/10.1101/2022.02.14.480334
https://doi.org/10.1101/2022.02.14.480334
Autor:
Christoph Noppen, Doris Popovic, Christian L. Althaus, Lorenz Risch, Olivier Kobel, Deborah Penet, Sinem Kas, Martin Ackermann, Chaoran Chen, Ivan Topolsky, Lara Fuhrmann, Ina Nissen, Katharina Jahn, Rebecca Denes, Melyssa Elies, Christiane Beckmann, Keith Harshman, Christian Beisel, Tim Roloff, Simon Grüter, Natascha Santacroce, Kim Philipp Jablonski, Nadia Wohlwend, Maria Domenica Moccia, Catharine Aquino, Adrian Egli, Niko Beerenwinkel, Lennart Opitz, Maurice Redondo, Henri Pegeot, Jana S. Huisman, Thomas Bodmer, Laurent Kaiser, Ioannis Xenarios, Ralph Schlapbach, Andreia Cabral de Gouvea, Madlen Stange, Sarah Nadeau, Laura Neff, Jay Tracy, David Dreifuss, Elodie Burcklen, Tanja Stadler, Griffin White, Isabella Eckerle, Marc Manceau, Anthony Blin, Lorenzo Cerutti, Mirjam Feldkamp, Emmanouil T. Dermitzakis, Martin Risch, Andrea Patrignani, Timothy Sykes
BackgroundIn December 2020, the United Kingdom (UK) reported a SARS-CoV-2 Variant of Concern (VoC) which is now named B.1.1.7. Based on initial data from the UK and later data from other countries, this variant was estimated to have a transmission fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f82afd63e94f7440a155f036cb33ab20
https://doi.org/10.1101/2021.03.05.21252520
https://doi.org/10.1101/2021.03.05.21252520
Asymmetric localization and translation of mRNAs is used by single cells to sense their environment and integrate extrinsic cues with the appropriate cellular response. Here we investigate the extent to which endosomes impact subcellular patterning o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30f25a040381d3a03b25f49d060fa79
https://doi.org/10.1101/2020.07.17.208652
https://doi.org/10.1101/2020.07.17.208652
Publikováno v:
Cell Systems
Summary A long-standing question in quantitative biology is the relationship between mRNA and protein levels of the same gene. Here, we measured mRNA and protein abundance, the phenotypic state, and the population context in thousands of single human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b469ce18825a7724491644cefaf2fe8
https://pubmed.ncbi.nlm.nih.gov/30342881
https://pubmed.ncbi.nlm.nih.gov/30342881
Publikováno v:
Nature Medicine
Ubiquitination is crucial for a plethora of physiological processes, including cell survival and differentiation and innate and adaptive immunity. In recent years, considerable progress has been made in the understanding of the molecular action of ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55da7861b1a4808d49c14a5d9b7b227
https://doi.org/10.1038/nm.3739
https://doi.org/10.1038/nm.3739
Autor:
Doris Popovic, Ivan Dikic
Publikováno v:
The Biochemist. 34:24-30
Autophagy is an evolutionarily conserved intracellular degradation process, through which large cellular cargos are sequestered into double-membrane vesicles (autophagosomes) and delivered to the lysosome. Starvation-induced autophagy represents a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2894f61b318e1b4811a4509c62775c2d
https://doi.org/10.1042/bio03402024
https://doi.org/10.1042/bio03402024
Autor:
David G. McEwan, Doris Popovic, Janoš Terzić, Ivan Dikic, Philipp Wild, Angelo Occhipinti, Vladimir V. Rogov, Ji Zhang, Alexis Rozenknop, Vladimir Kirkin, Frank Löhr, Ivana Novak, Paul A. Ney, Andreas S. Reichert, Volker Dötsch
Publikováno v:
EMBO reports. 11:45-51
Autophagy is the cellular homeostatic pathway that delivers large cytosolic materials for degradation in the lysosome. Recent evidence indicates that autophagy mediates selective removal of protein aggregates, organelles and microbes in cells. Yet, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eb208058390f9fa9a95d2c484270d5
https://doi.org/10.1038/embor.2009.256
https://doi.org/10.1038/embor.2009.256
Autor:
Hironori Suzuki, Sagar Bhogaraju, Philippe Pierre, Anja Kirchof, Karthik Maddi, David G. McEwan, Diana Miranda de Stegmann, Fraser P. Coxon, Soichi Wakatsuki, Ivan Dikic, Seigo Terawaki, Miep H. Helfrich, Doris Popovic, Evelina Gatti, Andrea Gubas, Christian Behrends, Daniela Stadel
Publikováno v:
Molecular Cell
The lysosome is the final destination for degradation of endocytic cargo, plasma membrane constituents, and intracellular components sequestered by macroautophagy. Fusion of endosomes and autophagosomes with the lysosome depends on the GTPase Rab7 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32eaff8f05faa169352d20aab988f086
https://pubmed.ncbi.nlm.nih.gov/25574946
https://pubmed.ncbi.nlm.nih.gov/25574946