Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Doris Nonner"'
Autor:
Stephanie Adamczak, MRoss Bullock, Doris Nonner, Frank J. Brand, Gerhard Dahl, Gordon A Dale, Robert W. Keane, W. Dalton Dietrich, Juan Pablo de Rivero Vaccari
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
The central nervous system (CNS) is an active participant in the innate immune response to infection and injury. In these studies, we show embryonic cortical neurons express a functional, deoxyribonucleic acid (DNA)-responsive, absent in melanoma 2 (
Autor:
Ellen F. Barrett, Janet D. Talbot, John N. Barrett, Kyle Wicomb, Doris Nonner, Zhongsheng Zhang
Publikováno v:
Experimental neurology. 285
In mutant superoxide dismutase 1 (SOD1) mouse models of familial amyotrophic lateral sclerosis (fALS) some of the earliest signs of morphological and functional damage occur in the motor nerve terminals that innervate fast limb muscles. This study te
Autor:
Osama Saleh, Carlos T. Moraes, Ellen F. Barrett, Doris Nonner, John N. Barrett, Michael G. White
Publikováno v:
Journal of Neurophysiology. 108:2203-2214
Previous work demonstrated that hyperthermia (43°C for 2 h) results in delayed, apoptotic-like death in striatal neuronal cultures. We investigated early changes in mitochondrial function induced by this heat stress. Partial depolarization of the mi
Publikováno v:
Neurochemical Research. 33:1852-1858
Activation of cyclin dependent kinases (Cdks) contributes to neuronal death following ischemia. We used oxygen-glucose deprivation (OGD) in septal neuronal cultures to test for possible roles of cell cycle proteins in neuronal survival. Increased cdc
Publikováno v:
Neuroscience. 135:73-80
Overexpression of Bcl-xl, a member of the Bcl-2 protein family, is reported to protect from a variety of stresses involving delayed cell death. We tested the ability of Bcl-xl overexpression to protect primary cultures of embryonic rat septal neurons
Publikováno v:
Journal of Neurochemistry. 87:958-968
Hyperthermia can contribute to brain damage both during development and post-natally. We used rat embryonic striatal neurons in culture to study mechanisms underlying hyperthermia-induced neuronal death. Heat stress at 43 degrees C for 2 h produced n
Autor:
Celik Kayalar, Doris Nonner, Dale E. Bredesen, Robert W. Keane, Anu Srinivasan, John C. Reed, Hong Gang Wang, Lyndon M. Foster, Maria Pia Testa, Tonis Ord
Publikováno v:
Journal of Neuroscience Research. 48:168-180
Members of the interleukin-1β-converting enzyme (ICE)/CED-3 protease family have been implicated in apoptosis in both vertebrates and invertebrates. Using primary culture methods, we report that neurons and astrocytes require the activity of the ICE
Autor:
Gordon A Dale, Gerhard Dahl, M. R. Bullock, W. D. Dietrich, Frank J. Brand, Robert W. Keane, Doris Nonner, J. P. De Rivero Vaccari, Stephanie Adamczak
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 36:456-456
Pyroptotic neuronal cell death mediated by the AIM2 inflammasome Adamczak SE, de Rivero Vaccari JP, Dale G, Brand FJ 3rd, Nonner D, Bullock MR, Dahl GP, Dietrich WD, Keane RW Journal of Cerebral Blood Flow & Metabolism 2014; 34: 621–629 .
Publikováno v:
Experimental Neurology. 122:196-208
Choline acetyltransferase (ChAT) activity and survival of acetylcholinesterase (AChE)-positive neurons were measured in low-density cultures of embryonic (Day 14-15) rat septum exposed to various sequences of nerve growth factor (NGF) exposure and de
Publikováno v:
Experimental Neurology. 118:309-316
Serum neurotoxicity was studied by adding whole or fractionated serum (adult human, adult horse, or newborn calf) to neuron-rich cultures prepared from various regions of embryonic (Days 14–15) rat brain, including spinal cord, ventral mesencephalo