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of 9
pro vyhledávání: '"Doris Loh"'
Autor:
Doris Loh, Russel J. Reiter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5835 (2023)
The swift rise in acceptance of molecular principles defining phase separation by a broad array of scientific disciplines is shadowed by increasing discoveries linking phase separation to pathological aggregations associated with numerous neurodegene
Externí odkaz:
https://doaj.org/article/27a958b2a74a4201a0c2c73c347b2cbf
Autor:
Doris Loh, Russel J. Reiter
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8122 (2022)
The relentless, protracted evolution of the SARS-CoV-2 virus imposes tremendous pressure on herd immunity and demands versatile adaptations by the human host genome to counter transcriptomic and epitranscriptomic alterations associated with a wide ra
Externí odkaz:
https://doaj.org/article/5453c4746b8b4e3b95ef670f90dc81b1
Autor:
Doris Loh, Russel J. Reiter
Publikováno v:
Molecules, Vol 27, Iss 3, p 705 (2022)
The unique ability to adapt and thrive in inhospitable, stressful tumor microenvironments (TME) also renders cancer cells resistant to traditional chemotherapeutic treatments and/or novel pharmaceuticals. Cancer cells exhibit extensive metabolic alte
Externí odkaz:
https://doaj.org/article/90437e0784f046429973239136fe5de7
Autor:
Jorge R. Miranda-Massari, Alondra P. Toro, Doris Loh, Jose R. Rodriguez, Raul Morales Borges, Victor Marcial-Vega, Jose Olalde, Miguel J. Berdiel, Neil H. Riordan, Juan Manuel Martinez, Armando Gil, Michael J. Gonzalez
Publikováno v:
Life, Vol 11, Iss 12, p 1341 (2021)
Currently available anti-viral drugs may be useful in reducing the viral load but are not providing the necessary physiological effects to reduce the SARS-CoV-2 complications efficiently. Treatments that provide better clinical outcomes are urgently
Externí odkaz:
https://doaj.org/article/6a0f3a203f6f4f9693f63ac3fa83de31
Autor:
Doris Loh, Russel J. Reiter
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1483 (2021)
Biomolecular condensates are membraneless organelles (MLOs) that form dynamic, chemically distinct subcellular compartments organizing macromolecules such as proteins, RNA, and DNA in unicellular prokaryotic bacteria and complex eukaryotic cells. Sep
Externí odkaz:
https://doaj.org/article/26d31df43e3f4bd1a22b18bae7c3e300
Autor:
Russel J Reiter, Doris Loh
Publikováno v:
Melatonin Research. 5:186-191
This commentary explores the leading edge of current understanding of the potential interactions associated with melatonin and the regulation of membraneless organelles (MLOs) formed via liquid‐liquid phase separation (LLPS) presented in recently p
Autor:
Doris Loh
Publikováno v:
Melatonin Research. 3:380-416
The rapid escalation of pandemic health threats associated with the novel, pathogenic SARS-CoV-2 coronavirus poses unprecedented challenges as proven effective vaccines and drugs have yet to be produced. Refractory hypoxemia and myocardial injury hav
Autor:
Russel Reiter, Doris Loh
Publikováno v:
International Journal of Molecular Sciences. 23:8122
The relentless, protracted evolution of the SARS-CoV-2 virus imposes tremendous pressure on herd immunity and demands versatile adaptations by the human host genome to counter transcriptomic and epitranscriptomic alterations associated with a wide ra