Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Doris Joy Espiritu"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 291:F588-F596
Sodium bicarbonate cotransporter 1 (NBC1) mediates 80% of bicarbonate reabsorption by the kidney, but the molecular determinants for activity, targeting, and cell membrane stability are poorly understood. We generated truncation mutants involving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b176080be2f177eb8ef108b8d431a595
https://doi.org/10.1152/ajprenal.00361.2005
https://doi.org/10.1152/ajprenal.00361.2005
Publikováno v:
Journal of Membrane Biology. 191:141-148
The basolateral Na+/HCO3- cotransporter (NBC) is the major pathway for bicarbonate reabsorption in the renal proximal tubule cells. The cotransporter activity is enhanced by 10% CO2. Phosphatidylinositol 3-kinase (PI3K) has been shown to regulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff3475e19afe0a0a97c22a41e9a35a1
https://doi.org/10.1007/s00232-002-1051-3
https://doi.org/10.1007/s00232-002-1051-3
Autor:
Arlene Uy, Doris Joy Espiritu, Joseph M. Vitello, Zhi H. Huang, Theodore Mazzone, Ai Xuan Holterman
Publikováno v:
Metabolism: clinical and experimental. 60(12)
Important differences in gene expression have been documented in adipocytes derived from specific adipose tissue depots. We have previously documented an important role for adipocyte apolipoprotein E (apoE) in modulating adipocyte and adipose tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3f5065d05f9bb901c9af3459effa38
https://pubmed.ncbi.nlm.nih.gov/21664633
https://pubmed.ncbi.nlm.nih.gov/21664633
Endogenous adipocyte apolipoprotein E (apoE) plays an important role in adipocyte lipoprotein metabolism and lipid flux. A potential role for hyperglycemia in regulating adipocyte apoE expression and triglyceride metabolism was examined. Exposure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733d3ef87cdd6c7fa03da21fadd97d80
https://europepmc.org/articles/PMC2957866/
https://europepmc.org/articles/PMC2957866/
Autor:
Doris Joy Espiritu, Theodore Mazzone
Publikováno v:
Diabetes
OBJECTIVE—Endogenous expression of apolipoprotein E (apoE) has a significant impact on adipocyte lipid metabolism and is markedly suppressed in obesity. Adipose tissue oxidant stress is emerging as an important mediator of adipocyte dysfunction. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90cec1fbf4367fe2e96ea91ad664e24
https://pubmed.ncbi.nlm.nih.gov/18678613
https://pubmed.ncbi.nlm.nih.gov/18678613
Publikováno v:
Seminars in nephrology. 26(5)
The role of the Na + -coupled HCO 3 − transporter (NBC) family is indispensable in acid-base homeostasis. Almost all tissues express a member of the NBC family. NBC has been studied extensively in the kidney and plays a role in proximal tubule HCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f7fec0bbe6a871a6433105d7be8ded
https://pubmed.ncbi.nlm.nih.gov/17071329
https://pubmed.ncbi.nlm.nih.gov/17071329
Autor:
Doris Joy Espiritu, Jose A.L. Arruda, F. T. Kear, V.C. Ibañez, Oscar Noboa, R.B. Robey, Ofelia S. Ruiz, A. A. Bernardo
Publikováno v:
The Journal of membrane biology. 187(2)
Angiotensin II (AII) plays an important role in renal proximal tubular acidification via the costimulation of basolateral Na/HCO3 cotransporter (NBC) and apical Na/H exchanger (NHE) activities. These effects are mediated by specific G protein-coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a74bbd00e0efc43ea97bf5300d6cda7
https://pubmed.ncbi.nlm.nih.gov/12029370
https://pubmed.ncbi.nlm.nih.gov/12029370