COVID-19 and chronic diabetes: the perfect storm for reactivation tuberculosis?: a case series

Autor: Genesis P. Aguillón-Durán, Ericka Prieto-Martínez, Doris Ayala, Juan García, John M. Thomas, Juan Ignacio García, Brandon Michael Henry, Jordi B. Torrelles, Joanne Turner, Eder Ledezma-Campos, Blanca I. Restrepo

Publikováno v: Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)

Abstract Background The coronavirus disease 2019 pandemic is predicted to have a net negative effect on tuberculosis control, with an estimated excess of 6.3 million tuberculosis cases and 1.4 million deaths by 2025. Programmatic issues such as the l

Externí odkaz: https://doaj.org/article/e41eead8254a44868b0214c6a4a84c13

Differential Role of Type 2 Diabetes as a Risk Factor for Tuberculosis in the Elderly versus Younger Adults

Autor: Blanca I. Restrepo, Julia M. Scordo, Génesis P. Aguillón-Durán, Doris Ayala, Ana Paulina Quirino-Cerrillo, Raúl Loera-Salazar, America Cruz-González, Jose A. Caso, Mateo Joya-Ayala, Esperanza M. García-Oropesa, Alejandra B. Salinas, Leonardo Martinez, Larry S. Schlesinger, Jordi B. Torrelles, Joanne Turner

Publikováno v: Pathogens, Vol 11, Iss 12, p 1551 (2022)

The elderly are understudied despite their high risk of tuberculosis (TB). We sought to identify factors underlying the lack of an association between TB and type 2 diabetes (T2D) in the elderly, but not adults. We conducted a case–control study in

Externí odkaz: https://doaj.org/article/74721901dd4d42b0aa47347e5d75d3fe

Novel Automation of an Enzyme-Linked Immunosorbent Spot Assay Testing Method: Comparable Diagnostic Performance of the T-SPOT. TB Test Using Manual Density Gradient Cell Isolation versus Automated Positive Selection with the T-Cell Select Kit

Autor: Shu-Hua Wang, Murgesean V. S. Rajaram, Andre Trollip, Qian Wu, Doris Ayala, Danyelle Garza, Marielena A. Benavidez, Kelsie Fox, Genesis P. Aguillón-Durán, Erika A. Vargas-Orozco, Lou Torres, Lianbo Yu, S. Rumel Ahmed, Megan Aspden, Thomas Jackson-Soutter, Catherine Coxon, Ruth Brignall, Blanca I. Restrepo

Publikováno v: Journal of Clinical Microbiology. 60

The diagnosis of latent tuberculosis (TB) infection (LTBI) is critical to improve TB treatment and control, and the T-SPOT. TB test is a commercial enzyme-linked immunosorbent spot assay used for this purpose. The objective of the study was to increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52488e12117cba9df53984953fd07772
https://doi.org/10.1128/jcm.00551-22

Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people

Autor: Mateo Joya-Ayala, Francisco Mora-Guzmán, Doris Ayala, Alejandro Villafañez, Génesis P. Aguillón-Durán, Ana Paulina Quirino-Cerrillo, Larry S. Schlesinger, Jordi B. Torrelles, Blanca I. Restrepo, Eder Ledezma-Campos, Eminé Rodríguez-Reyna, Joanne Turner, Julia M. Scordo

Publikováno v: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
International Journal of Infectious Diseases, Vol 111, Iss, Pp 85-91 (2021)

SUMMARY: Background: Interferon gamma release assays (IGRAs) are used to detect latent Mycobacterium tuberculosis (M.tb) infection (LTBI) in adults, but their performance in older people is not well-established. We evaluated IGRAs for LTBI detection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068b58f3fd75801e57f0bf3847bad687
https://pubmed.ncbi.nlm.nih.gov/34389503