Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Doris, Kretzschmar"'
Autor:
Karon Rowe, Nora E. Gray, Jonathan A. Zweig, Alexander Law, Natascha Techen, Claudia S. Maier, Amala Soumyanath, Doris Kretzschmar
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
IntroductionCentella asiatica (CA) is known in Ayurvedic medicine as a rejuvenating herb with particular benefits in the nervous system. Two groups of specialized metabolites found in CA and purported to contribute to its beneficial effects are trite
Externí odkaz:
https://doaj.org/article/7ce26c79578d41d18d33aaf049e4d3b2
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106429- (2024)
The most prominent symptom of Alzheimer's disease (AD) is cognitive decline; however, sleep and other circadian disruptions are also common in AD patients. Sleep disruptions have been connected with memory problems and therefore the changes in sleep
Externí odkaz:
https://doaj.org/article/fdc3fa36063345fea0e5bb800225068b
Autor:
Jun Yang, Yujuan Song, Alexander D. Law, Conner J. Rogan, Kelsey Shimoda, Danijel Djukovic, Jeffrey C. Anderson, Doris Kretzschmar, David A. Hendrix, Jadwiga M. Giebultowicz
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Blue light (BL) is becoming increasingly prevalent in artificial illumination, raising concerns about its potential health hazard to humans. In fact, there is evidence suggesting that acute BL exposure may lead to oxidative stress and death of retina
Externí odkaz:
https://doaj.org/article/86ef98bb2b204c55afe828ffcf464c6c
Autor:
Alexander D. Law, Marlène Cassar, Dani M. Long, Eileen S. Chow, Jadwiga M. Giebultowicz, Anjana Venkataramanan, Roland Strauss, Doris Kretzschmar
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105770- (2022)
Although mutations in the microtubules-associated protein Tau have long been connected with several neurodegenerative diseases, the underlying molecular mechanisms causing these tauopathies are still not fully understood. Studies in various models su
Externí odkaz:
https://doaj.org/article/5662c98be9934fca882e7065b3adf1e7
Autor:
Kirsten M. Wright, Janis McFerrin, Armando Alcázar Magaña, Joanne Roberts, Maya Caruso, Doris Kretzschmar, Jan F. Stevens, Claudia S. Maier, Joseph F. Quinn, Amala Soumyanath
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, inherent va
Externí odkaz:
https://doaj.org/article/0047909dd93442a8aa619fec9842b565
Autor:
Trevor R. Nash, Eileen S. Chow, Alexander D. Law, Samuel D. Fu, Elzbieta Fuszara, Aleksandra Bilska, Piotr Bebas, Doris Kretzschmar, Jadwiga M. Giebultowicz
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 5, Iss 1, Pp 1-8 (2019)
Abstract Light is necessary for life, but prolonged exposure to artificial light is a matter of increasing health concern. Humans are exposed to increased amounts of light in the blue spectrum produced by light-emitting diodes (LEDs), which can inter
Externí odkaz:
https://doaj.org/article/b5a13df9da704333ac49a61936553663
Autor:
Olena Odnokoz, Kyle Nakatsuka, Corbin Wright, Jovelyn Castellanos, Vladimir I. Klichko, Doris Kretzschmar, William C. Orr, Svetlana N. Radyuk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mitochondrial dysfunction often leads to neurodegeneration and is considered one of the main causes of neurological disorders, such as Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and other age-related diseases. Mitochondrial dysfunc
Externí odkaz:
https://doaj.org/article/397786c0847e48f793cf824a98d3c3c7
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
A hallmark feature of Alzheimer’s disease (AD) and other Tauopathies, like Frontotemporal Dementia with Parkinsonism linked to chromosome 17 (FTDP-17), is the accumulation of neurofibrillary tangles composed of the microtubule-associated protein Ta
Externí odkaz:
https://doaj.org/article/6b32aeac766e4116acc3e5210b2b4f86
Autor:
Doris Kretzschmar
Publikováno v:
Metabolites, Vol 12, Iss 4, p 284 (2022)
Patatin-like phospholipase domain-containing protein 6 (PNPLA6), originally called Neuropathy Target Esterase (NTE), belongs to a family of hydrolases with at least eight members in mammals. PNPLA6/NTE was first identified as a key factor in Organoph
Externí odkaz:
https://doaj.org/article/5a0d02fe201049bb9e3c68ca8f90ef45
Autor:
Kadine Cabey, Dani M. Long, Alexander Law, Nora E. Gray, Christine McClure, Maya Caruso, Parnian Lak, Kirsten M. Wright, Jan F. Stevens, Claudia S. Maier, Amala Soumyanath, Doris Kretzschmar
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 121 (2022)
Due to an increase in the aging population, age-related diseases and age-related changes, such as diminished cognition and sleep disturbances, are an increasing health threat. It has been suggested that an increase in oxidative stress underlies many
Externí odkaz:
https://doaj.org/article/b2d5687849d94cd080ef083284f8e42c