Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dorina Belotti"'
Autor:
Andrea Resovi, Perla Persichitti, Laura Brunelli, Lucia Minoli, Patrizia Borsotti, Giulia Garattini, Matteo Tironi, Erica Dugnani, Miriam Redegalli, Giulia De Simone, Roberta Pastorelli, Maria Rosa Bani, Lorenzo Piemonti, Deane F. Mosher, Raffaella Giavazzi, Giulia Taraboletti, Dorina Belotti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background The pancreatic microenvironment has a defensive role against cancer but it can acquire tumor-promoting properties triggered by multiple mechanisms including alterations in the equilibrium between proteases and their inhibitors. Th
Externí odkaz:
https://doaj.org/article/4bc68fabcf3a4866bfd7e59ee7c138f6
Autor:
Andrea Resovi, Maria Rosa Bani, Luca Porcu, Alessia Anastasia, Lucia Minoli, Paola Allavena, Paola Cappello, Francesco Novelli, Aldo Scarpa, Eugenio Morandi, Anna Falanga, Valter Torri, Giulia Taraboletti, Dorina Belotti, Raffaella Giavazzi
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-14 (2018)
Abstract The clinical management of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of reliable biomarkers. This study investigated the value of soluble stroma‐related molecules as PDAC biomarkers. In the first exploratory phase, 12
Externí odkaz:
https://doaj.org/article/e47a6b26a16a45e391d78f0c384f31c5
Autor:
Andrea Resovi, Patrizia Borsotti, Tommaso Ceruti, Alice Passoni, Massimo Zucchetti, Alexander Berndt, Bruce L. Riser, Giulia Taraboletti, Dorina Belotti
Publikováno v:
Cells, Vol 9, Iss 4, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Externí odkaz:
https://doaj.org/article/814b2712dc644b48b6b7bb898871a43d
Autor:
Katiuscia Bonezzi, Dorina Belotti, Brian J. North, Carmen Ghilardi, Patrizia Borsotti, Andrea Resovi, Paolo Ubezio, Antonella Riva, Raffaella Giavazzi, Eric Verdin, Giulia Taraboletti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 846-854 (2012)
Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and unrelated to their antiproliferative effect. The molecular mechanism of this anti-motility activity is poorly understood. In
Externí odkaz:
https://doaj.org/article/324bba01ddad45f9bda06f2d628005cb
Autor:
Andrea Resovi, Patrizia Borsotti, Fabio Sangalli, Enrico Davoli, Alexander Berndt, Lorena Zentilin, Massimo Zucchetti, Raffaella Giavazzi, Alice Passoni, Dorina Belotti, Giovanni Valbusa, Denise Pinessi, Mauro Giacca, Giulia Taraboletti, Lavinia Morosi, Elena Carlessi
Publikováno v:
Matrix Biology. :22-36
The disorganized and inefficient tumor vasculature is a major obstacle to the delivery and efficacy of antineoplastic treatments. Antiangiogenic agents can normalize the tumor vessels, improving vessel function and boosting the distribution and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b7e7d23aa52880fa5d7cbb53fe2ddc
https://doi.org/10.1016/j.matbio.2021.10.001
https://doi.org/10.1016/j.matbio.2021.10.001
Autor:
Andrea David Re Cecconi, Mara Barone, Mara Forti, Martina Lunardi, Alfredo Cagnotto, Mario Salmona, Davide Olivari, Lorena Zentilin, Andrea Resovi, Perla Persichitti, Dorina Belotti, Federica Palo, Nobuyuki Takakura, Hiroyasu Kidoya, Rosanna Piccirillo
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1814
Cancer cachexia consists of dramatic body weight loss with rapid muscle depletion due to imbalanced protein homeostasis. We found that the mRNA levels of apelin decrease in muscles from cachectic hepatoma-bearing rats and three mouse models of cachex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c5dd72c08177cc495424bd3a432517
https://pubmed.ncbi.nlm.nih.gov/35406586
https://pubmed.ncbi.nlm.nih.gov/35406586
Autor:
Dorina Belotti, Massimo Zucchetti, Andrea Resovi, Patrizia Borsotti, Alexander Berndt, Bruce L Riser, Giulia Taraboletti, Alice Passoni, Tommaso Ceruti
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24a5e124d7e6b60fb96aac77464450f
http://europepmc.org/articles/PMC7226963
http://europepmc.org/articles/PMC7226963
Autor:
Antonella Bugatti, Denise Pinessi, Giorgio Colombo, Giulia Paiardi, Giulia Taraboletti, Deane F. Mosher, Paola Chiodelli, Douglas S. Annis, Alessandro Gori, Elisabetta Moroni, Dorina Belotti, Patrizia Borsotti, Laura Carminati, Chiara Foglieni, Marco Rusnati, Renato Longhi
Publikováno v:
Angiogenesis (Dordr., Online) 22 (2019): 133–144. doi:10.1007/s10456-018-9644-3
info:cnr-pdr/source/autori:Rusnati M.; Borsotti P.; Moroni E.; Foglieni C.; Chiodelli P.; Carminati L.; Pinessi D.; Annis D.S.; Paiardi G.; Bugatti A.; Gori A.; Longhi R.; Belotti D.; Mosher D.F.; Colombo G.; Taraboletti G./titolo:The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2)/doi:10.1007%2Fs10456-018-9644-3/rivista:Angiogenesis (Dordr., Online)/anno:2019/pagina_da:133/pagina_a:144/intervallo_pagine:133–144/volume:22
info:cnr-pdr/source/autori:Rusnati M.; Borsotti P.; Moroni E.; Foglieni C.; Chiodelli P.; Carminati L.; Pinessi D.; Annis D.S.; Paiardi G.; Bugatti A.; Gori A.; Longhi R.; Belotti D.; Mosher D.F.; Colombo G.; Taraboletti G./titolo:The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2)/doi:10.1007%2Fs10456-018-9644-3/rivista:Angiogenesis (Dordr., Online)/anno:2019/pagina_da:133/pagina_a:144/intervallo_pagine:133–144/volume:22
Thrombospondin (TSP)-1 and TSP-2 share similar structures and functions, including a remarkable antiangiogenic activity. We have previously demonstrated that a mechanism of the antiangiogenic activity of TSP-1 is the interaction of its type III repea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ca2338121360f320faba713901f669
http://www.cnr.it/prodotto/i/400593
http://www.cnr.it/prodotto/i/400593
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1912, p 1912 (2021)
Cancers, Vol 13, Iss 1912, p 1912 (2021)
Simple Summary Tumors rely on blood vessels to grow and metastasize. Malignant tumors can employ different strategies to create a functional vascular network. Tumor cells can use normal processes of vessel formation but can also employ cancer-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83bb3e73bdef73ace81e6c6134a5e73
https://doi.org/10.3390/cancers13081912
https://doi.org/10.3390/cancers13081912
Autor:
Giulia Taraboletti, Denise Pinessi, Laura Carminati, Raffaella Giavazzi, Lucia Minoli, Dorina Belotti, Maurizio D'Incalci, Patrizia Borsotti
Publikováno v:
Carcinogenesis. 40(2)
Trabectedin is a marine-derived antineoplastic drug. Besides targeting the cancer cells, trabectedin has a peculiar activity on the tumor microenvironment with marked effects on the vasculature and the immune response. Because a favorable microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29980a0a366e8b9b9f59c93e9c4e70cf
https://pubmed.ncbi.nlm.nih.gov/30544170
https://pubmed.ncbi.nlm.nih.gov/30544170