Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dorien J. M. Peters"'
Autor:
Wouter H. vanMegen, Teun J. vanHoutert, Caro Bos, Dorien J. M. Peters, Jeroen H. F. deBaaij, Joost G. J. Hoenderop
Publikováno v:
Physiological Reports, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease (ADPKD), which is characterized by the formation of fluid‐filled cysts in the kidney. In a subset of ADPKD patients, reduced blood calcium (Ca2+) and magnesium (
Externí odkaz:
https://doaj.org/article/eba8173c9eea463d8246e51aca8aa886
Autor:
Xuewen Song, Wouter N. Leonhard, Anish A. Kanhai, Gregory R. Steinberg, York Pei, Dorien J. M. Peters
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder and an important cause of end stage renal disease (ESRD). Tolvaptan (a V2R antagonist) is the first disease modifier drug for treatment of ADPKD, but
Externí odkaz:
https://doaj.org/article/48d465f4278047878c9c9eb75b978439
Autor:
Claudia Dafinger, Markus M. Rinschen, Lori Borgal, Carolin Ehrenberg, Sander G. Basten, Mareike Franke, Martin Höhne, Manfred Rauh, Heike Göbel, Wilhelm Bloch, F. Thomas Wunderlich, Dorien J. M. Peters, Dirk Tasche, Tripti Mishra, Sandra Habbig, Jörg Dötsch, Roman-Ulrich Müller, Jens C. Brüning, Thorsten Persigehl, Rachel H. Giles, Thomas Benzing, Bernhard Schermer, Max C. Liebau
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 6, Pp 1-17 (2018)
Cell cilia: Protein crucial for function identified A protein involved in building and maintaining thin protrusions from cell surfaces called cilia is implicated in “ciliopathies”, diseases in which ciliary function is disrupted. These include po
Externí odkaz:
https://doaj.org/article/8de13e7b325345b1995d5f539ec1dcfd
Autor:
Ileana Cristea, Hugo Abarca, Anne E. Christensen Mellgren, Milana Trubnykova, Roya Mehrasa, Dorien J. M. Peters, Gunnar Houge, Raoul C. M. Hennekam, Eyvind Rødahl, Ove Bruland, Cecilie Bredrup
Publikováno v:
FEBS letters. Wiley-Blackwell
Ocular pterygium–digital keloid dysplasia (OPDKD) is a rare hereditary disease characterized by corneal ingrowth of vascularized conjunctival tissue early in life. Later, patients develop keloids on fingers and toes but are otherwise healthy. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faae597b6f3f313d39dfd08051c7960c
https://pure.amc.nl/en/publications/a-pellino2-variant-is-associated-with-constitutive-nlrp3-inflammasome-activation-in-a-family-with-ocular-pterygiumdigital-keloid-dysplasia(d974df55-4334-45ef-bd49-50f070d4f84d).html
https://pure.amc.nl/en/publications/a-pellino2-variant-is-associated-with-constitutive-nlrp3-inflammasome-activation-in-a-family-with-ocular-pterygiumdigital-keloid-dysplasia(d974df55-4334-45ef-bd49-50f070d4f84d).html
Publikováno v:
iScience, 26(6)
The cellular diversity and complexity of the kidney are on par with its physiological intricacy. Although our anatomical understanding of the different segments and their functions is supported by a plethora of research, the identification of distinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5930fa2e232c2f30242de2df5a6720
https://doi.org/10.1101/2022.07.02.498501
https://doi.org/10.1101/2022.07.02.498501
Autor:
Leticia Maria de Souza Cordeiro, Lauren Bainbridge, Nagavardhini Devisetty, David H. McDougal, Dorien J. M. Peters, Kavaljit H. Chhabra
Publikováno v:
Diabetologia, 65(6), 1032-1047. SPRINGER
Diabetologia
Diabetologia
Aims/hypothesis: Renal GLUT2 is increased in diabetes, thereby enhancing glucose reabsorption and worsening hyperglycaemia. Here, we determined whether loss of Glut2 (also known as Slc2a2) specifically in the kidneys would reverse hyperglycaemia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b87b14d9a29cab8b7bd58f4a16ce70
https://doi.org/10.1007/s00125-022-05676-8
https://doi.org/10.1007/s00125-022-05676-8
Autor:
Eric H J, Verschuren, Charlotte, Castenmiller, Dorien J M, Peters, Francisco J, Arjona, René J M, Bindels, Joost G J, Hoenderop
Publikováno v:
Nature reviews. Nephrology. 16(6)
The kidney is a remarkable organ that accomplishes the challenge of removing waste from the body and simultaneously regulating electrolyte and water balance. Pro-urine flows through the nephron in a highly dynamic manner and adjustment of the reabsor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c37af11400953fdaa10105742106aff
https://pubmed.ncbi.nlm.nih.gov/32127698
https://pubmed.ncbi.nlm.nih.gov/32127698
Autor:
Alexander E Ivliev, Peter A C 't Hoen, Willeke M C van Roon-Mom, Dorien J M Peters, Marina G Sergeeva
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35618 (2012)
Cilia are cell organelles that play important roles in cell motility, sensory and developmental functions and are involved in a range of human diseases, known as ciliopathies. Here, we search for novel human genes related to cilia using a strategy th
Externí odkaz:
https://doaj.org/article/8e4883524535438db23ebc653ece11f3
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 839
Planar cell polarity (PCP) is the polarization of cells within the plane of an epithelial cell layer. PCP is important in many tissues in different processes. In the kidney, it is hypothesized to be important in acquiring and maintaining correct tubu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddb554b9db8a868124dcf67721a50115
https://pubmed.ncbi.nlm.nih.gov/22218907
https://pubmed.ncbi.nlm.nih.gov/22218907
Autor:
Hester, Happé, Annemieke M, van der Wal, Wouter N, Leonhard, Steven J, Kunnen, Martijn H, Breuning, Emile, de Heer, Dorien J M, Peters
Publikováno v:
The Journal of pathology. 224(1)
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive deterioration of renal function and formation of cysts, and is an important cause of end-stage renal disease. Previously we showed that tubular epithelial injury acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1489da9050bf5c22086ce811a8b523b5
https://pubmed.ncbi.nlm.nih.gov/21381034
https://pubmed.ncbi.nlm.nih.gov/21381034