Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dorian Forte"'
Autor:
Giulia Corradi, Dorian Forte, Gianluca Cristiano, Andrea Polimeno, Marilena Ciciarello, Valentina Salvestrini, Lorenza Bandini, Valentina Robustelli, Emanuela Ottaviani, Michele Cavo, Darina Ocadlikova, Antonio Curti
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute myeloid leukemia (AML) is an aggressive heterogeneous disease characterized by several alterations of the immune system prompting disease progression and treatment response. The therapies available for AML can affect lymphocyte function, limiti
Externí odkaz:
https://doaj.org/article/a5d55294093e4929a53b57474c48442f
Autor:
Zijian Fang, Giuditta Corbizi Fattori, Thomas McKerrell, Rebecca H. Boucher, Aimee Jackson, Rachel S. Fletcher, Dorian Forte, Jose-Ezequiel Martin, Sonia Fox, James Roberts, Rachel Glover, Erica Harris, Hannah R. Bridges, Luigi Grassi, Alba Rodriguez-Meira, Adam J. Mead, Steven Knapper, Joanne Ewing, Nauman M. Butt, Manish Jain, Sebastian Francis, Fiona J. Clark, Jason Coppell, Mary F. McMullin, Frances Wadelin, Srinivasan Narayanan, Dragana Milojkovic, Mark W. Drummond, Mallika Sekhar, Hesham ElDaly, Judy Hirst, Maike Paramor, E. Joanna Baxter, Anna L. Godfrey, Claire N. Harrison, Simón Méndez-Ferrer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Current therapies for myeloproliferative neoplasms (MPNs) improve symptoms but have limited effect on tumor size. In preclinical studies, tamoxifen restored normal apoptosis in mutated hematopoietic stem/progenitor cells (HSPCs). TAMARIN Pha
Externí odkaz:
https://doaj.org/article/16a1a95232b2462f94a84a299c0e1020
Autor:
Chiara Sartor, Emanuela Ottaviani, Jacopo Nanni, Raffaele Ciruolo, Gianluca Cristiano, Letizia Zannoni, Federico Zingarelli, Lorenza Bandini, Agnese Patuelli, Claudia Venturi, Valentina Robustellu, Dorian Forte, Michele Cavo, Antonio Curti, Cristina Papayannidis
Publikováno v:
HemaSphere, Vol 7, p e3793940 (2023)
Externí odkaz:
https://doaj.org/article/cb99162c69b04187973b67d6842d8cb9
Autor:
Darina Ocadlikova, Giulia Corradi, Dorian Forte, Gianluca Cristiano, Michele Cavo, Antonio Curti
Publikováno v:
HemaSphere, Vol 7, p e97655cf (2023)
Externí odkaz:
https://doaj.org/article/299a6dd7fb8040a1b58dac1a7afb502f
Autor:
Dorian Forte, Roberto Maria Pellegrino, Sara Trabanelli, Tommaso Tonetti, Francesca Ricci, Mara Cenerenti, Giorgia Comai, Pierluigi Tazzari, Tiziana Lazzarotto, Sandra Buratta, Lorena Urbanelli, Ghazal Narimanfar, Husam B. R. Alabed, Cristina Mecucci, Gaetano La Manna, Carla Emiliani, Camilla Jandus, Vito Marco Ranieri, Michele Cavo, Lucia Catani, Francesca Palandri
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionExtracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 patients is not well determined. Here, we characterized the immunophe
Externí odkaz:
https://doaj.org/article/063796386a684852a9ac7b89cedea0b4
Autor:
Dorian Forte, Martina Barone, Cristina Morsiani, Giorgia Simonetti, Francesco Fabbri, Samantha Bruno, Erika Bandini, Daria Sollazzo, Salvatore Collura, Maria Chiara Deregibus, Giuseppe Auteri, Emanuela Ottaviani, Nicola Vianelli, Giovanni Camussi, Claudio Franceschi, Miriam Capri, Francesca Palandri, Michele Cavo, Lucia Catani
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Myelofibrosis (MF) is a clonal disorder of hemopoietic stem/progenitor cells (HSPCs) with high prevalence in elderly patients and mutations in three driver genes (JAK2, MPL, or CALR). Around 10–15% of patients are triple-negativ
Externí odkaz:
https://doaj.org/article/ea1e5111da3d4f6c9597a0561836a070
Autor:
Samantha Bruno, Lorenza Bandini, Agnese Patuelli, Valentina Robustelli, Claudia Venturi, Manuela Mancini, Dorian Forte, Sara De Santis, Cecilia Monaldi, Alessandra Grassi, Gabriella Chiurumbolo, Stefania Paolini, Gianluca Cristiano, Cristina Papayannidis, Chiara Sartor, Jacopo Nanni, Emanuela Ottaviani, Antonio Curti, Michele Cavo, Simona Soverini
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
FMS-like tyrosine kinase 3 (FLT3) is among the most common driver genes recurrently mutated in acute myeloid leukemia (AML), accounting for approximately 30% of cases. Activating mutations of the FLT3 receptor include internal tandem duplications (IT
Externí odkaz:
https://doaj.org/article/6bb2e31dbe434e4abe6e84f55b172a07
Autor:
Valentina Salvestrini, Marilena Ciciarello, Valentina Pensato, Giorgia Simonetti, Maria Antonella Laginestra, Samantha Bruno, Martina Pazzaglia, Elena De Marchi, Dorian Forte, Stefania Orecchioni, Giovanni Martinelli, Francesco Bertolini, Simon Méndez-Ferrer, Elena Adinolfi, Francesco Di Virgilio, Michele Cavo, Antonio Curti
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/b3cfa07c2d2f4e8e8e1110c40491f093
Autor:
Valentina Salvestrini, Marilena Ciciarello, Valentina Pensato, Giorgia Simonetti, Maria Antonella Laginestra, Samantha Bruno, Martina Pazzaglia, Elena De Marchi, Dorian Forte, Stefania Orecchioni, Giovanni Martinelli, Francesco Bertolini, Simon Méndez-Ferrer, Elena Adinolfi, Francesco Di Virgilio, Michele Cavo, Antonio Curti
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The contribution of cell-extrinsic factors in Acute Myeloid Leukemia (AML) generation and persistence has gained interest. Bitter taste receptors (TAS2Rs) are G protein-coupled receptors known for their primary role as a central warning signal to ind
Externí odkaz:
https://doaj.org/article/17d43cda59c54f258b12c4d38055eb40
Autor:
Martina Barone, Lucia Catani, Francesca Ricci, Marco Romano, Dorian Forte, Giuseppe Auteri, Daniela Bartoletti, Emanuela Ottaviani, Pier Luigi Tazzari, Nicola Vianelli, Michele Cavo, Francesca Palandri
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Myelofibrosis (MF) is characterized by chronic inflammation and hyper-activation of the JAK-STAT pathway. Infections are one of the main causes of morbidity/mortality. Therapy with Ruxolitinib (RUX), a JAK1/2 inhibitor, may further increase the infec
Externí odkaz:
https://doaj.org/article/6dcbe6ddbddd40ca95f38f7cec8aa42b