Zobrazeno 1 - 10
of 711
pro vyhledávání: '"Dorian, B"'
Publikováno v:
In Trends in Immunology October 2024 45(10):738-749
Autor:
Danielle D. Dang, Vikram Chandrashekhar, Vibhu Chandrashekhar, Nagela Ghabdanzanluqui, Russell H. Knutsen, Matthew A. Nazari, Likitha Nimmagadda, Danielle R. Donahue, Dorian B. McGavern, Beth A. Kozel, John D. Heiss, Karel Pacak, Zhengping Zhuang, Jared S. Rosenblum
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102367- (2023)
Summary: Mapping cranial vasculature and adjacent neurovascular interfaces in their entirety will enhance our understanding of central nervous system function in any physiologic state. We present a workflow to visualize in situ murine vasculature and
Externí odkaz:
https://doaj.org/article/ae9471c45db847b68da91dbec8d63a83
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury
Autor:
Hannah Mason, Ganesha Rai, Arina Kozyr, Nathaniel De Jonge, Emily Gliniewicz, Lars J. Berg, Gal Wald, Cayce Dorrier, Mark J. Henderson, Alexey Zakharov, Tristan Dyson, John Audley, Anthony M. Pettinato, Elias Carvalho Padilha, Pranav Shah, Xin Xu, Thomas L. Leto, Anton Simeonov, Kol A. Zarember, Dorian B. McGavern, John I. Gallin
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102611- (2023)
NADPH oxidases (NOX's), and the reactive oxygen species (ROS) they produce, play an important role in host defense, thyroid hormone synthesis, apoptosis, gene regulation, angiogenesis and other processes. However, overproduction of ROS by these enzym
Externí odkaz:
https://doaj.org/article/31bbeff5a1be41638e89f840fa625181
Autor:
Bonnie Huang, James D. Phelan, Silvia Preite, Julio Gomez-Rodriguez, Kristoffer H. Johansen, Hirofumi Shibata, Arthur L. Shaffer, Qin Xu, Brendan Jeffrey, Martha Kirby, Stacie Anderson, Yandan Yang, Selamawit Gossa, Dorian B. McGavern, Louis M. Staudt, Pamela L. Schwartzberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
T follicular helper (Tfh) and T help type 1 (Th1) cells both arise from naïve CD4 T cells, but detailed knowledge of their differentiation remains incomplete. Here the authors pursue an in vivo CRISPR screen to identify genes, focusing on druggable
Externí odkaz:
https://doaj.org/article/f2c40bd54ddf4ca49421a503fe6ad4d6
Autor:
Chen, Hui, Smith, Mindy, Herz, Jasmin, Li, Tong, Hasley, Rebecca, Le Saout, Cecile, Zhu, Ziang, Cheng, Jie, Gronda, Andres, Martina, José A., Irusta, Pablo M., Karpova, Tatiana, McGavern, Dorian B., Catalfamo, Marta
Publikováno v:
In iScience 19 November 2021 24(11)
Autor:
Lago, Natalia, Kaufmann, Fernanda N., Negro-Demontel, María Luciana, Alí-Ruiz, Daniela, Ghisleni, Gabriele, Rego, Natalia, Arcas-García, Andrea, Vitureira, Nathalia, Jansen, Karen, Souza, Luciano M., Silva, Ricardo A., Lara, Diogo R., Pannunzio, Bruno, Abin-Carriquiry, Juan Andrés, Amo-Aparicio, Jesús, Martin-Otal, Celia, Naya, Hugo, McGavern, Dorian B., Sayós, Joan, López-Vales, Rubèn, Kaster, Manuella P., Peluffo, Hugo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar . 117(12), 6651-6662.
Externí odkaz:
https://www.jstor.org/stable/26929582
Autor:
Elsaesser, Heidi J., Mohtashami, Mahmood, Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Boukhaled, Giselle M., McGavern, Dorian B., Zúñiga-Pflücker, Juan Carlos, Brooks, David G.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar 01. 117(10), 5420-5429.
Externí odkaz:
https://www.jstor.org/stable/26929255
Autor:
Li Liu, Steve Dodd, Ryan D Hunt, Nikorn Pothayee, Tatjana Atanasijevic, Nadia Bouraoud, Dragan Maric, E Ashley Moseman, Selamawit Gossa, Dorian B McGavern, Alan P Koretsky
Publikováno v:
eLife, Vol 11 (2022)
Central nervous system (CNS) infections are a major cause of human morbidity and mortality worldwide. Even patients that survive, CNS infections can have lasting neurological dysfunction resulting from immune and pathogen induced pathology. Developin
Externí odkaz:
https://doaj.org/article/2ea941d974e74f36b28237158415d6c8
Autor:
Hui Chen, Mindy Smith, Jasmin Herz, Tong Li, Rebecca Hasley, Cecile Le Saout, Ziang Zhu, Jie Cheng, Andres Gronda, José A. Martina, Pablo M. Irusta, Tatiana Karpova, Dorian B. McGavern, Marta Catalfamo
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103387- (2021)
Summary: CD8 T cells are essential for adaptive immunity against viral infections. Protease activated receptor 1 (PAR1) is expressed by CD8 T cells; however, its role in T cell effector function is not well defined. Here we show that in human CD8 T c
Externí odkaz:
https://doaj.org/article/059bb0b455fd410090bd8cec3665286e
Autor:
Hannah D. Mason, Alexis M. Johnson, Nicole A. Mihelson, Panagiotis Mastorakos, Dorian B. McGavern
Publikováno v:
JCI Insight, Vol 6, Iss 19 (2021)
Repetitive mild traumatic brain injuries (mTBI) disrupt CNS barriers, the erosion of which has been linked to long-term neurodegenerative and psychiatric conditions. Although much attention has been devoted to CNS vasculature following mTBI, little i
Externí odkaz:
https://doaj.org/article/6a2dff98410a4e768286cd0677dd7e68