Výsledky vyhledávání - "Doreen Wendholt"

ProSAP-interacting Protein 1 (ProSAPiP1), a Novel Protein of the Postsynaptic Density That Links the Spine-associated Rap-Gap (SPAR) to the Scaffolding Protein ProSAP2/Shank3

Autor: Eckart D. Gundelfinger, Christina Spilker, Michael R. Kreutz, Anna Dolnik, Kenji Sobue, Christian Proepper, Karl-Heinz Smalla, Angelika Schmitt, Juergen Bockmann, Doreen Wendholt, Tobias M. Boeckers

Publikováno v: Journal of Biological Chemistry. 281:13805-13816

ProSAPs/Shanks are a family of proteins that have a major scaffolding function for components of the postsynaptic density (PSD) of excitatory brain synapses. Members of the family harbor a variety of domains for protein-protein interactions, one of w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1262b1211c0c1197d9650548a1451368
https://doi.org/10.1074/jbc.m601101200

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Bradykinin-Induced Pulmonary Vasoconstriction Is Time and Inducible Nitric Oxide Synthase Dependent in a Peritonitis Sepsis Model

Autor: Andreas W. Sielenkämper, Hugo Van Aken, Hendrik Freise, Doreen Wendholt, Jan H. Hilpert, Lars G. Fischer

Publikováno v: Anesthesia & Analgesia. 99:864-871

In an isolated perfused lung model, bradykinin induced pulmonary vasoconstriction in rats made septic by the injection of lipopolysaccharide (LPS). To mimic the pathophysiology of sepsis in humans more closely, we investigated pulmonary endothelial i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16e1c550163a567127b793307474fca
https://doi.org/10.1213/01.ane.0000133000.65613.f5

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Insulin-induced expression of the activity-regulated cytoskeleton-associated gene (ARC) in human neuroblastoma cells requires p21ras, mitogen-activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-independent

Autor: Angelika Barnekow, Iskender Teber, Joachim Kremerskothen, Doreen Wendholt

Publikováno v: Neuroscience Letters. 321:153-156

We examined the effect of insulin on the expression of the activity-regulated cytoskeleton-associated gene (ARC), an effector immediate early gene with a proposed role in memory formation. In human SH-SY5Y neuroblastoma cells, application of insulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b386125bd2c5f7b07277a4431c049209
https://doi.org/10.1016/s0304-3940(01)02532-0

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The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis

Autor: Beate Eckes, Svetlana Frank, Doreen Wendholt, Wim B. van den Berg, Simon Strietholt, Adelheid Korb-Pap, Noreen Pundt, Leo A. B. Joosten, Marvin A. Peters, Thomas Pap, George Kollias

Publikováno v: Arthritis and Rheumatism, 64, 1359-68
Arthritis and Rheumatism, 64, 5, pp. 1359-68

Item does not contain fulltext OBJECTIVE: Integrin alpha2beta1 functions as a major receptor for type I collagen on different cell types, including fibroblasts and inflammatory cells. Although in vitro data suggest a role for alpha2beta1 integrin in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f13eb77271bcb04197bc107c6c7a78a
https://www.ncbi.nlm.nih.gov/pubmed/22083543

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Establishment of a matrix-associated transepithelial resistance invasion assay to precisely measure the invasive potential of synovial fibroblasts

Autor: C Wunrau, Berno Dankbar, Katharina Freyth, Thomas Pap, Eva-Maria Schnaeker, Katja Neugebauer, Uwe Hansen, Doreen Wendholt, Noreen Pundt

Publikováno v: Arthritis and rheumatism. 60(9)

Objective Synovial fibroblasts (SFs) contribute to several aspects of the pathogenesis of rheumatoid arthritis (RA) and have been implicated most prominently in the progressive destruction of articular cartilage. Targeting the invasive phenotype of R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e953296b7787d6e90e2927fa5c4aee
https://pubmed.ncbi.nlm.nih.gov/19714628

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Human Multipotent Mesenchymal Stromal Cells (MSC) Exhibit Broad Spectrum Antimicrobial Effector Functions Mediated by Indoleamine 2,3-Dioxygenase (IDO)

Autor: Claudia Woite, Stuhlsatz S, Huelya Buelle, Dagmar Dilloo, Roland Meisel, Kathrin Heseler, Doreen Wendholt, Wilfried Schwippert, Walter Daeubener

Publikováno v: Blood. 110:1922-1922

Multipotent mesenchymal stromal cells (MSCs) exhibit multilineage differential potential, support hematopoiesis, and potently inhibit proliferation and effector function of various immune cells. Based on these properties MSCs are currently under inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc690dcc98ff01d52e96e47ffb93c602
https://doi.org/10.1182/blood.v110.11.1922.1922

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