Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Doreen Siegel"'
Autor:
Lisa Graf, Falko Tesch, Felix Gräßer, Lorenz Harst, Doreen Siegels, Jochen Schmitt, Susanne Abraham
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background About 2% of the German population are affected by psoriasis. A growing number of cost-intensive systemic treatments are available. Surveys have shown high proportions of patients with moderate to severe psoriasis are not adequatel
Externí odkaz:
https://doaj.org/article/5e68b8e88ff84810bd43dffe717c5a4a
FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis
Autor:
Maximilian Schuff, Nabila Bardine, Cornelia Donow, Doreen Siegel, Franz Oswald, Walter Knöchel
Publikováno v:
Developmental Biology. 337(2):259-273
Forkhead box (Fox) transcription factors of subclass O are involved in cell survival, proliferation, apoptosis, cell metabolism and prevention of oxidative stress. FoxO genes are highly conserved throughout evolution and their functions were analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7491b404199fa3f3b7c1e7b4025c2dc
Publikováno v:
Mechanisms of Development. 126:974-989
The maintenance of pluripotency in mammalian embryonic stem cells depends upon the expression of regulatory genes like Oct3/4 and Sox2. While homologues of these genes are also characterized in non-mammalian vertebrates, like birds, amphibians and fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc6964e53c403b127872c8e1d948420
https://doi.org/10.1016/j.mod.2009.09.007
https://doi.org/10.1016/j.mod.2009.09.007
Publikováno v:
Journal of Biological Chemistry. 283:34168-34177
The balance between differentiation signals and signals maintaining the undifferentiated state of embryonic cells ensures proper formation of germ layers. The nodal/activin pathway represents one of the major signaling chains responsible for the diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3348bfe466baff3b9e161624490aa62a
https://doi.org/10.1074/jbc.m803532200
https://doi.org/10.1074/jbc.m803532200
Publikováno v:
The EMBO Journal. 26:2942-2954
VegT and beta-Catenin are key players in the hierarchy of factors that are required for induction and patterning of mesendoderm in Xenopus embryogenesis. By descending the genetic cascades, cells lose their pluripotent status and are determined to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3259dad0e25f456862c6108a5a7670
https://doi.org/10.1038/sj.emboj.7601736
https://doi.org/10.1038/sj.emboj.7601736
Publikováno v:
Mechanisms of Development. 123:614-625
Three POU factors of subclass V, Oct-25, Oct-60 and Oct-91 are expressed in Xenopus oocytes and early embryos. We here demonstrate that vegetal overexpression of Oct-25, Oct-60, Oct-91 or mammalian Oct-3/4 suppresses mesendoderm formation in Xenopus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b30ddec83befc8dd6bcc0defa1f07b4
https://doi.org/10.1016/j.mod.2006.06.004
https://doi.org/10.1016/j.mod.2006.06.004
Autor:
Walter Knöchel, Karin Bundschu, Maximilian Schuff, Cornelia Donow, Melanie Philipp, Doreen Siegel, Nicole Heymann
Publikováno v:
Stem cells and development. 21(8)
Nanog is a homeodomain transcription factor associated with the acquisition of pluripotency. Genome analyses of lower and higher vertebrates revealed that the existence of Nanog is restricted to gnathostomata but absent from agnatha and invertebrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d9f2086e232278649b5e2f104d4ddd
https://pubmed.ncbi.nlm.nih.gov/21967637
https://pubmed.ncbi.nlm.nih.gov/21967637
Autor:
Katja Scholz, Salim Abdelilah-Seyfried, Janna Krueger, Christian Klein, Ferdinand le Noble, Justus Veerkamp, Joep Brinkmann, Janine Mikutta, Doreen Siegel, Dong Liu
Publikováno v:
Development (Cambridge, England). 138(10)
Endodermal organogenesis requires a precise orchestration of cell fate specification and cell movements, collectively coordinating organ size and shape. In Caenorhabditis elegans, uncoordinated-53 (unc-53) encodes a neural guidance molecule that dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea758b6bef40122925c546649aeb908
https://pubmed.ncbi.nlm.nih.gov/21471154
https://pubmed.ncbi.nlm.nih.gov/21471154