Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Doreen Pachow"'
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
PDF file - 65K, Effect of temsirolimus in a subcutaneous xenograft mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4955f734c1f5b59bfdba3f0ceb043277
https://doi.org/10.1158/1078-0432.22448777.v1
https://doi.org/10.1158/1078-0432.22448777.v1
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Purpose: Meningiomas are frequent intracranial or spinal neoplasms, which recur frequently and can show aggressive clinical behaviour. We elucidated the impact of the integrin inhibitor cilengitide on migration, proliferation, and radiosensitization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadb72e040d297f2e93460fea31975ba
https://doi.org/10.1158/1078-0432.c.6521400
https://doi.org/10.1158/1078-0432.c.6521400
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 1 - PDF file 57K, integrin mRNA expression in meningiomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0283af208c75bdcad1dae5b16f37d3
https://doi.org/10.1158/1078-0432.22448442.v1
https://doi.org/10.1158/1078-0432.22448442.v1
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
PDF file - 69K, Real time-PCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0640ccf264982b7473425f8b4a26c18b
https://doi.org/10.1158/1078-0432.22448780.v1
https://doi.org/10.1158/1078-0432.22448780.v1
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 3 - PDF file 43K, Overall survival of mice treated with cilengitide and control animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d62ffa2bf41711aa8e79ae449192319
https://doi.org/10.1158/1078-0432.22448436
https://doi.org/10.1158/1078-0432.22448436
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 2 - PDF file 128K, Cell cycle analyses under cilengitide treatment. Meningioma cell lines treated with cilengitide and analysed for cell cycle changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c2b2fd4fc77316694dc2c55f71768
https://doi.org/10.1158/1078-0432.22448439.v1
https://doi.org/10.1158/1078-0432.22448439.v1
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
Purpose: To evaluate the mTORC1 (mammalian target of rapamycin complex 1) pathway in meningiomas and to explore mTORC1 as a therapeutic target in meningioma cell lines and mouse models.Experimental Design: Tissue microarrays (53 meningiomas of all WH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737c54afacb6895f24e318fe97f850ed
https://doi.org/10.1158/1078-0432.c.6521483.v1
https://doi.org/10.1158/1078-0432.c.6521483.v1
Autor:
Christina Blücher, Elmar Kirches, Raimund Firsching, Christian Mawrin, Werner E.K. Braunsdorf, Maren Wallesch, Doreen Pachow, Jan-Peter Warnke
Publikováno v:
Journal of the Neurological Sciences. 380:112-121
E-Cadherin has been suggested to be involved in meningioma progression but is also known as a key player of epithelial to mesenchymal transition (EMT). We wondered whether the adherens junction protein E-Cadherin, the tight junction protein Zo-1, and
Autor:
Jan-Peter Warnke, Gerburg Keilhoff, Eva Hebert, Annette Wilisch-Neumann, Doreen Pachow, Werner E.K. Braunsdorf, Christian Mawrin, Natalie Waldt, Thomas Schneider, Elmar Kirches, Tabea Steffen
Publikováno v:
Journal of neuro-oncology. 138(2)
Mesenchymal stem cells (MSC) have been found in various cancers and were discussed to influence tumor biology. Cells fulfilling the complete MSC criteria, including surface marker expression (CD73, CD90, CD105) and tri-lineage differentiation, have b
Publikováno v:
Neuro-Oncology. 17:189-199
Inhibition of the mammalian target of rapamycin (mTOR) signaling pathway has become an attractive target for human cancer therapy. Hyperactivation of mTOR has been reported in both sporadic and syndromic (hereditary) brain tumors. In contrast to the