Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Doreen N, Palsgrove"'
Autor:
Alessandro Leal, Nicole C. T. van Grieken, Doreen N. Palsgrove, Jillian Phallen, Jamie E. Medina, Carolyn Hruban, Mark A. M. Broeckaert, Valsamo Anagnostou, Vilmos Adleff, Daniel C. Bruhm, Jenna V. Canzoniero, Jacob Fiksel, Marianne Nordsmark, Fabienne A. R. M. Warmerdam, Henk M. W. Verheul, Dick Johan van Spronsen, Laurens V. Beerepoot, Maud M. Geenen, Johanneke E. A. Portielje, Edwin P. M. Jansen, Johanna van Sandick, Elma Meershoek-Klein Kranenbarg, Hanneke W. M. van Laarhoven, Donald L. van der Peet, Cornelis J. H. van de Velde, Marcel Verheij, Remond Fijneman, Robert B. Scharpf, Gerrit A. Meijer, Annemieke Cats, Victor E. Velculescu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Identifying patients that will respond to a particular therapy remains a key challenge in precision oncology. Here, in gastric cancer, the authors show that circulating tumour DNA can predict recurrence, provided that the signal from white blood cell
Externí odkaz:
https://doaj.org/article/e873283671f243d3ba192161c80d36a7
Autor:
Fausto J. Rodriguez, Mindy K. Graham, Jacqueline A. Brosnan-Cashman, John R. Barber, Christine Davis, M. Adelita Vizcaino, Doreen N. Palsgrove, Caterina Giannini, Melike Pekmezci, Sonika Dahiya, Murat Gokden, Michael Noë, Laura D. Wood, Christine A. Pratilas, Carol D. Morris, Allan Belzberg, Jaishri Blakeley, Christopher M. Heaphy
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract The presence of Alternative lengthening of telomeres (ALT) and/or ATRX loss, as well as the role of other telomere abnormalities, have not been formally studied across the spectrum of NF1-associated solid tumors. Utilizing a telomere-specifi
Externí odkaz:
https://doaj.org/article/3454d938fe7347fc81ef6b72dd035460
Autor:
Carlos G. Romo, Doreen N. Palsgrove, Ananyaa Sivakumar, Christen R. Elledge, Lawrence R. Kleinberg, Kaisorn L. Chaichana, Christopher D. Gocke, Fausto J. Rodriguez, Matthias Holdhoff
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Gliomas with 1p/19q-codeletion as well as mutation of isocitrate dehydrogenase (IDH) 1 are typically characterized as oligodendrogliomas with comparatively good response to treatment with radiation and chemotherapy. Case presentat
Externí odkaz:
https://doaj.org/article/7e1f5d2a9ad64279989e2c325510829f
Autor:
Rajal B. Shah, Doreen N. Palsgrove, Neil B. Desai, Jeffrey Gagan, Amanda Mennie, Ganesh Raj, Raquibul Hannan
Publikováno v:
Modern Pathology. 35:1468-1474
Locally relapsed prostate cancer (PCa) after radiation therapy (RT) is associated with substantial morbidity and mortality. Morphological and molecular consequences that may contribute to RT resistance and local recurrence remain poorly understood. L
Autor:
Mark R, Hopkins, Doreen N, Palsgrove, Brigitte M, Ronnett, Russell, Vang, Jeffrey, Lin, Tricia A, Murdock
Publikováno v:
American Journal of Surgical Pathology. 46:1611-1622
Human papillomavirus (HPV)-independent primary endometrial squamous cell carcinoma (PESCC) is a rare but aggressive subtype of endometrial carcinoma for which little is known about the genomic characteristics. Traditional criteria have restricted the
Autor:
Doreen N. Palsgrove, Lisa M. Rooper, Todd M. Stevens, Christina Shin, Douglas D. Damm, Jeffrey Gagan, Julia A. Bridge, Lester D. R. Thompson, Prasad R. Koduru, Justin A. Bishop
Publikováno v:
Head and Neck Pathology. 16:1146-1156
GLI1 is a transcription factor protein that has recently gained recognition in a morphologically distinct group of epithelioid soft tissue tumors characterized by GLI1 fusions or amplifications. The head and neck region, particularly the tongue, is a
Autor:
Pedram Argani, Satish K. Tickoo, Andres Matoso, Christine A. Pratilas, Rohit Mehra, Maria Tretiakova, Mathilde Sibony, Alan K. Meeker, Ming-Tseh Lin, Victor E. Reuter, Jonathan I. Epstein, Jeffrey Gagan, Doreen N. Palsgrove
Publikováno v:
Am J Surg Pathol
The genetics of nephroblastoma (Wilms tumor) occurring in adults is largely unknown, as studies have largely been limited to isolated case reports. We, therefore, studied 14 adult Wilms tumors for genetic alterations, using expanded targeted sequenci
Autor:
Victor E. Velculescu, Julie R. Brahmer, Matthew D. Hellmann, Jamie E. Chaft, Drew M. Pardoll, Rachel Karchin, Robert B. Scharpf, Janis Taube, Jennifer L. Sauter, James M. Isbell, Malcolm V. Brock, Edward Gabrielson, Qing Kay Li, Peter Illei, Franco Verde, Christos Georgiades, Josephine Feliciano, Benjamin Levy, Christine L. Hann, Doreen N. Palsgrove, Lamia Rhymee, Tricia R. Cottrell, Kellie N. Smith, Vilmos Adleff, Alessandro Leal, Jillian Phallen, Samuel Rosner, Daniel C. Bruhm, I.K. Ashok Sivakumar, Kristen Marrone, Jarushka Naidoo, Carolyn Hruban, Noushin Niknafs, James R. White, Patrick M. Forde, Valsamo Anagnostou
Despite the initial successes of immunotherapy, there is an urgent clinical need for molecular assays that identify patients more likely to respond. Here, we report that ultrasensitive measures of circulating tumor DNA (ctDNA) and T-cell expansion ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9635a5d6f44ac7214b2e198664dbe1a1
https://doi.org/10.1158/0008-5472.c.6511197.v1
https://doi.org/10.1158/0008-5472.c.6511197.v1
Autor:
Victor E. Velculescu, Julie R. Brahmer, Matthew D. Hellmann, Jamie E. Chaft, Drew M. Pardoll, Rachel Karchin, Robert B. Scharpf, Janis Taube, Jennifer L. Sauter, James M. Isbell, Malcolm V. Brock, Edward Gabrielson, Qing Kay Li, Peter Illei, Franco Verde, Christos Georgiades, Josephine Feliciano, Benjamin Levy, Christine L. Hann, Doreen N. Palsgrove, Lamia Rhymee, Tricia R. Cottrell, Kellie N. Smith, Vilmos Adleff, Alessandro Leal, Jillian Phallen, Samuel Rosner, Daniel C. Bruhm, I.K. Ashok Sivakumar, Kristen Marrone, Jarushka Naidoo, Carolyn Hruban, Noushin Niknafs, James R. White, Patrick M. Forde, Valsamo Anagnostou
Supplementary Table S1. Summary of patient characteristics Supplementary Table S2. Summary of plasma samples analyzed Supplementary Table S3. Summary of peripheral blood lymphocytes and tumor infiltrating lymphocytes samples analyzed Supplementary Ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124d0b4bc633214944bd209dff0fdd47
https://doi.org/10.1158/0008-5472.22422375
https://doi.org/10.1158/0008-5472.22422375
Autor:
Hatim Husain, Victor E. Velculescu, Robert B. Scharpf, Valsamo Anagnostou, Elizabeth Weihe, Vilmos Adleff, Parissa Keshavarzian, Daniel C. Bruhm, Christopher D. Gocke, Doreen N. Palsgrove, Stephen Cristiano, Jamie E. Medina, Jacob Fiksel, Julie R. Brahmer, Kristen A. Marrone, Jarushka Naidoo, Patrick M. Forde, Brian D. Woodward, Alessandro Leal, Jillian Phallen
The supplementary tables for "Early noninvasive detection of response to targeted therapy in non-small cell lung cancer" report clinical characteristics of patients analyzed (1), serial timepoints analyzed (2), genes analyzed (3), a summary of genomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba01d05eb1651648d31488dbb700b8b
https://doi.org/10.1158/0008-5472.22423020.v1
https://doi.org/10.1158/0008-5472.22423020.v1