Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Doreen LePage"'
Autor:
Jeffrey L. Browning, Robert Hoffman, Dajun Yang, Fabienne Mackay, Shelia M. Violette, Werner Meier, Holly Prentice, Thomas Crowell, Joseph Amatucci, Konrad Miatkowski, Amie Carmillo, Mitchell Reff, Stephen Fawell, Matt Jarpe, William Yang, Erika Silverio, Glenna Heaney, Linda Griffith, Jane Ding, Cindy Bottiglio, Rebecca Kelly, Kathleen Wortham, Kendall Szeliga, Xianghong Xu, Steve Perrin, Norman Allaire, Weike Zeng, Apinya Ngam-ek, Alex Lukashin, Ellen Garber, Véronique Bailly, Cheryl Wilson, Doreen LePage, Matvey Lukashev
Supplementary Tables 1-3, Figure 1 from Targeting the Lymphotoxin-β Receptor with Agonist Antibodies as a Potential Cancer Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949c15071769d873b18784a3e14ade10
https://doi.org/10.1158/0008-5472.22366529.v1
https://doi.org/10.1158/0008-5472.22366529.v1
Data from Targeting the Lymphotoxin-β Receptor with Agonist Antibodies as a Potential Cancer Therapy
Autor:
Jeffrey L. Browning, Robert Hoffman, Dajun Yang, Fabienne Mackay, Shelia M. Violette, Werner Meier, Holly Prentice, Thomas Crowell, Joseph Amatucci, Konrad Miatkowski, Amie Carmillo, Mitchell Reff, Stephen Fawell, Matt Jarpe, William Yang, Erika Silverio, Glenna Heaney, Linda Griffith, Jane Ding, Cindy Bottiglio, Rebecca Kelly, Kathleen Wortham, Kendall Szeliga, Xianghong Xu, Steve Perrin, Norman Allaire, Weike Zeng, Apinya Ngam-ek, Alex Lukashin, Ellen Garber, Véronique Bailly, Cheryl Wilson, Doreen LePage, Matvey Lukashev
The lymphotoxin-β receptor (LTβR) is a tumor necrosis factor receptor family member critical for the development and maintenance of various lymphoid microenvironments. Herein, we show that agonistic anti-LTβR monoclonal antibody (mAb) CBE11 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b7ca6b964258f446d078607d18b2c0
https://doi.org/10.1158/0008-5472.c.6495179
https://doi.org/10.1158/0008-5472.c.6495179
Autor:
Mark Cornebise, C. Nickerson-Nutter, Brian M. Dolinski, Stuart J. Perper, Steve Adams, Alan Gill, Diane R Leone, Doreen Lepage, Keith Giza, R. B. Pepinsky, L. L. Chen, Eric T. Whalley, Roy R. Lobb, K. Wortham, Petter Russell C, Daniel Scott, Wen-Cherng Lee, A. Chakraborty
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:742-750
Integrin alpha4beta1 plays an important role in inflammatory processes by regulating the migration of leukocytes into inflamed tissues. Previously, we identified BIO5192 [2(S)-{[1-(3,5-dichloro-benzenesulfonyl)-pyrrolidine-2(S)-carbonyl]-amino}-4-[4-
Autor:
Roy R. Lobb, Mark Cornebise, Russell C. Petter, C. Nickerson-Nutter, K. Wortham, Doreen Lepage, R. B. Pepinsky, Wen-Cherng Lee, Steve Adams, L. L. Chen, Daniel Scott, J. C. Spell, Brian M. Dolinski, Alan Gill, W. Yang, Keith Giza, Stuart J. Perper, Eric T. Whalley, Diane R Leone
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:1150-1162
Integrin alpha 4 beta 1 plays an important role in inflammatory processes by regulating the migration of lymphocytes into inflamed tissues. Here we evaluated the biochemical, pharmacological, and pharmacodynamic properties and efficacy in experimenta
Autor:
Jonathan N. Mead, Feng Shan, Juswinder Singh, Lihong Sun, Michael J. Corbley, Serene Josiah, Claudio Chuaqui, H.-Kam Cheung, Xiamei Zhang, Erika Lorraine Silverio, P. Ann Boriack-Sjodin, Timothy Pontz, Scott Bowes, Miki N. Newman, Leona E. Ling, James L. Papadatos, Doreen Lepage, Robert M. Arduini, Wen-Cherng Lee
Publikováno v:
Transforming Growth Factor-β in Cancer Therapy, Volume II ISBN: 9781588297150
The multifunctional cytokine, TGF-β, is often overexpressed in human tumors and in preclinical studies has been demonstrated to have autocrine and paracrine protumor activities including immune evasion, invasiveness, epithelial to mesenchymal transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca322a8bc362e1edd29b79e1a404b73
https://doi.org/10.1007/978-1-59745-293-9_41
https://doi.org/10.1007/978-1-59745-293-9_41
Autor:
THOMAS FAIRCLOTH GLYNN, AVILES MARIN PABLO MANUEL, DOREEN LEPAGE, MIGUEL IZQUIERDO JESUS SAN, Atanasio
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Europe PubMed Central
instname
Europe PubMed Central
Filing Date: 2007-02-28.- Priority Data: US 60/813,606 (2006-02-28).
The present invention relates to combinations of aplidine or aplidine analogues with other antitumoral agents, and the use of these combinations in the treatment of cancer, in
The present invention relates to combinations of aplidine or aplidine analogues with other antitumoral agents, and the use of these combinations in the treatment of cancer, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7d4d63262e11c28e13170513e7501911
http://hdl.handle.net/10261/3251
http://hdl.handle.net/10261/3251
Autor:
Thomas Crowell, Xianghong Xu, Veronique Bailly, Konrad Miatkowski, Matvey E. Lukashev, Dajun Yang, Werner Meier, Holly Prentice, Stephen Fawell, Jeffrey L. Browning, Matthew Jarpe, Ellen Garber, Linda Griffith, Robert M. Hoffman, William Yang, Cindy Bottiglio, Joseph Amatucci, Amie N. Carmillo, Erika Lorraine Silverio, Alex Lukashin, Rebecca Kelly, Steve Perrin, Fabienne Mackay, Kathleen Wortham, Norman Allaire, Weike Zeng, Kendall Szeliga, Mitchell Reff, Glenna Heaney, Cheryl A. Wilson, Doreen Lepage, Jane Ding, Apinya Ngam-ek, Shelia M. Violette
Publikováno v:
Cancer research. 66(19)
The lymphotoxin-β receptor (LTβR) is a tumor necrosis factor receptor family member critical for the development and maintenance of various lymphoid microenvironments. Herein, we show that agonistic anti-LTβR monoclonal antibody (mAb) CBE11 inhibi
Autor:
Paul Rayhorn, Alphonse Galdes, Dingyi Wen, Thomas Engber, Doreen Lepage, Renee I. Shapiro, Shaoshan Wang, R. Blake Pepinsky, Frederick R. Taylor, Ellen Garber, Gerald S.B. Horan, Abhijit Chakraborty, Alan Gill
Publikováno v:
Journal of pharmaceutical sciences. 91(2)
The therapeutic effects of the Sonic hedgehog (Shh) have been difficult to evaluate because of its relatively short serum half-life. To address this issue polyethylene glycol modification (PEGylation) was investigated as an approach to improve system