Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Doreen Hooi"'
Autor:
Peter Fischer, Gary Telford, Doreen Hooi, Karima Righetti, Gopal P. Jadhav, Paul Williams, Barrie Kellam, David I. Pritchard, Siri Ram Chhabra
Publikováno v:
Journal of Medicinal Chemistry. 54:3348-3359
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone (1) is involved not only in bacterial activation but also in subversion of the host immune system, and this compound might thus be used as a template to desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a588211209ca7ee9b11a5317dc8be36
https://doi.org/10.1021/jm2001019
https://doi.org/10.1021/jm2001019
Autor:
Kevin Mortimer, Johanna Feary, A. Brown, Franco H. Falcone, Doreen Hooi, Andrea Venn, David I. Pritchard, John Britton
Publikováno v:
Clinical and Experimental Allergy
Summary Background Epidemiological studies suggest that hookworm infection protects against asthma, and therefore that hookworm infection may have a direct or an indirect therapeutic potential in this disease. We now report the first clinical trial o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7991c43240a6637ac8d04f91f66df225
https://doi.org/10.1111/j.1365-2222.2009.03433.x
https://doi.org/10.1111/j.1365-2222.2009.03433.x
Autor:
Kevin Mortimer, A. Brown, John Britton, Johanna Feary, Andrea Venn, Franco H. Falcone, David I. Pritchard, Doreen Hooi
Publikováno v:
Clinical and Experimental Allergy
Summary Background Epidemiological evidence suggests that hookworm infection protects against asthma. However, for ethical and safety reasons, before testing this hypothesis in a clinical trial in asthma it is necessary to establish whether experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138c322077b457dabd9e238530c06427
https://doi.org/10.1111/j.1365-2222.2009.03187.x
https://doi.org/10.1111/j.1365-2222.2009.03187.x
Autor:
A. Brown, Doreen Hooi, Leah Scott, P. C. Pearce, David I. Pritchard, Rebecca J. Hornby, Gareth D. Griffiths
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 78:936-945
Patent and pathologic infections of the human hookworm Necator americanus were established in the common marmoset (Callithrix jacchus). In a pilot study, a laboratory strain of N. americanus was compared with a fresh field isolate. Pathology was more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46679694c9dff3a3fbcc4996805b3dca
https://doi.org/10.4269/ajtmh.2008.78.936
https://doi.org/10.4269/ajtmh.2008.78.936
Autor:
Doreen Hooi, Alan Brown, Rupert J. Quinnell, Moses J. Bockarie, Rebecca Caddick, David I. Pritchard
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 77:860-865
A popular hypothesis to explain parasite survival in the presence of a pronounced T helper 2 phenotype in helminth-parasitized populations has been FcRI blockade by parasite-induced polyclonal IgE. To begin to test the hypothesis that FcRI-bearing ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091de3c6c760a816c4129a1852f6fbe8
https://doi.org/10.4269/ajtmh.2007.77.860
https://doi.org/10.4269/ajtmh.2007.77.860
Autor:
Lucy J. Wilkinson, Gareth D. Griffiths, Gary Telford, Doreen Hooi, David L. Cook, Christopher Green, David I. Pritchard
Publikováno v:
International Immunopharmacology. 5:525-540
Immune regulation, either via the autonomic nervous system or by a proposed “non-neuronal” cholinergic system, suggests that the immune system may be susceptible to perturbation by compounds affecting cholinergic function. Here, the current UK an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0af5a73568ee117ed587165bfa5d781
https://doi.org/10.1016/j.intimp.2004.10.014
https://doi.org/10.1016/j.intimp.2004.10.014
Autor:
Lucy J. Wilkinson, Gareth D. Griffiths, Doreen Hooi, A. Christopher Green, Gary Telford, Vivienne Worrall, David L. Cook, David I. Pritchard
Publikováno v:
International Immunopharmacology. 4:1455-1466
The current pretreatment against nerve agent poisoning deployed by the UK and US armed forces is the acetylcholinesterase (EC 3.1.1.7) inhibitor pyridostigmine bromide (PB). At higher doses, PB is also used to treat the autoimmune disease myasthenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8085ad7537397f0b0a481bf205ed56c
https://doi.org/10.1016/j.intimp.2004.06.009
https://doi.org/10.1016/j.intimp.2004.06.009
Publikováno v:
Oncogene. 23:4894-4902
Cell growth is promoted by mitogens and survival factors, which activate intracellular signalling pathways to control cell cycle progression and cellular integrity. Proliferation signals are transmitted through Ras and Rho family small G-proteins cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ba07270414a6df246745c5f88759e2
https://doi.org/10.1038/sj.onc.1207612
https://doi.org/10.1038/sj.onc.1207612
Autor:
S. J. B. Tendler, Doreen Hooi, Lindy G. Durrant, Ferenc Hudecz, Michael R. Price, M. Sekowski
Publikováno v:
Journal of Immunological Methods. 159:277-281
Monoclonal antibodies have been prepared against a synthetic peptide with a sequence corresponding to a repeated hydrophilic region of the protein core of the human MUC-2 gastrointestinal mucin. Peptide conjugates, prepared by glutaraldehyde cross-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceff1b496ef711ff1d7c806e505152d
https://doi.org/10.1016/0022-1759(93)90168-7
https://doi.org/10.1016/0022-1759(93)90168-7
Autor:
Johanna Feary, Daniel G. Blount, Alan Brown, Doreen Hooi, Andrea Venn, John Britton, David I. Pritchard, Gary Telford
Publikováno v:
The American journal of tropical medicine and hygiene. 81(5)
Data from epidemiologic studies suggest that hookworm infections, in establishing an immunologic phenotype conducive to parasite survival, may protect against the development of allergic disease. We describe immunologic findings from a clinical study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b67160a315a056cdf750f72d575e2f
https://pubmed.ncbi.nlm.nih.gov/19861631
https://pubmed.ncbi.nlm.nih.gov/19861631