Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Doreen Anders"'
Autor:
Julia Suchomel, Priya Agarwal, Doreen Anders, Kevin Hughes, Yang Tang, Rucha Sane, Astrid Scalori, Sunil Sharma, Sravanthi Cheeti
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract A study to determine the impact of cyclosporine (Neoral), an inhibitor of P‐gp, on the pharmacokinetics of pralsetinib (trade name GAVRETO®) was conducted in 15 healthy adult volunteers. A single 200 mg dose of pralsetinib was administere
Externí odkaz:
https://doaj.org/article/aac328372e5c492ca5f8e9f1ea06f1ca
Autor:
Kit Wun Kathy Cheung, Yang Tang, Doreen Anders, Teresa Barata, Astrid Scalori, Priya Agarwal, Rucha Sane, Sravanthi Cheeti
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 564 (2024)
Pralsetinib is a kinase inhibitor indicated for the treatment of metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer. Pralsetinib is primarily eliminated by the liver and hence hepatic impairment (HI) is likely
Externí odkaz:
https://doaj.org/article/36e760d984da4103856adc19adf5013b
Autor:
Alessandro Rambaldi, Margherita Maffioli, Alessandro M. Vannucchi, Brian Higgins, Bruno Kovic, Kate Burbury, Ruben A. Mesa, David M. Ross, Doreen Anders, Francesco Passamonti, Abdulraheem Yacoub, Tarec Christoffer El-Galaly, Aaron T. Gerds, Jeanne Palmer, John Mascarenhas, Vikas Gupta
Publikováno v:
Blood. 136:29-31
Background PV is a clonal myeloid neoplasm characterized by activating mutations in JAK2 and increased red blood cell production. Reduction of thrombosis risk through lowering of hematocrit (Hct) and thus blood viscosity is critical, but management o
Autor:
Kirsten Mundt, Benjamin M. Beckermann, Nastya Kassir, Christophe Schmitt, Candice Jamois, Magali Genevray, Claire Petry, Joy Yang, Doreen Anders
Publikováno v:
Blood. 136:7-8
Background: Myelosuppression, and especially severe and prolonged neutropenia, can make patients (pts) with acute myeloid leukemia (AML) susceptible to fatal infections. Idasanutlin (idasa), a MDM2 antagonist promoting p53 tumor suppressor activity,
Autor:
Anna Wirz-Justice, Christian Cajochen, Achim Pross, Jakub Späti, Oliver Stefani, Matthias Bues, Silvia Frey, Ralph Mager, Doreen Anders
Publikováno v:
Journal of the Society for Information Display. 20:266-272
— In commodity LC flat-panel displays, the traditional CCFL backlight is being replaced more and more by LEDs. The typical spectrum of LED-lit displays shows a significantly higher amount of blue light in the range around 464 nm. Blue light in this
Autor:
Kurt Kräuchi, Marcel Hofstetter, Judith Cann, Selim Orgül, Doreen Anders, Josef Flammer, Stephanie Vollenweider
Publikováno v:
Chronobiology International. 27:1609-1628
Heart-rate variability patterns of 18 women during a 40-h constant routine of prolonged wakefulness under controlled laboratory conditions were analyzed. The authors tested the circadian timing of the autonomic nervous system and the relationship bet
Autor:
Anna Wirz-Justice, Ralph Mager, Jakub Späti, Matthias Bues, Achim Pross, Oliver Stefani, Christian Cajochen, Doreen Anders, Sylvia Frey
Many people spend an increasing amount of time in front of computer screens equipped with light-emitting diodes (LED) with a short wavelength (blue range). Thus we investigated the repercussions on melatonin (a marker of the circadian clock), alertne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26363ee899d1cb0ad7331866fd6fa0f
https://publica.fraunhofer.de/handle/publica/225441
https://publica.fraunhofer.de/handle/publica/225441
Autor:
Ralph Mager, Dieter Spath, Matthias Bues, Achim Pross, Silvia Frey, Oliver Stefani, Doreen Anders, Christian Cajochen
Publikováno v:
SID Symposium Digest of Technical Papers. 41:1120
We present the results of clinical user studies comparing the effects of LED- vs. CCFL-backlit displays on humans, resulting from the emitted amount of 464 nm light. The LED-lit display causes significant effects on the user. We present a concept of