Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Doreen A. Spires"'
Publikováno v:
Journal of Investigative Dermatology. 83(5):394-398
The intradermal injection of 140 μg of Propionibacterium acnes (CN 6134) into the ears of female Sprague-Dawley rats produced a chronic inflammation with formation of acneiform lesions. Inflammation was characterized by more than a doubling of ear t
Autor:
Larry M. De Young, Cecil S. Cummins, Stephen J. Ballaron, Doreen A. Spires, Anthony C. Allison, John M. Young
Publikováno v:
Journal of Investigative Dermatology. (3):255-258
The ability of strains and fractions of killed propionibacteria suspensions to produce chronic rat ear inflammation after intradermal injection of 70-μg aliquots was highly correlated with production of splenomegaly in the mouse after i.p. injection
Autor:
Brad Loe, S. H. Unger, P. Cheung, S. Rouhafza, J. M. Young, K. C. Kappas, P. J. Maloney, M. C. Venuti, Doreen A. Spires, D. V. K. Murthy, Colin C. Beard, R. A. Simpson, M. Kruseman, G. H. Jones, A. H. Berks
Publikováno v:
ChemInform. 18
Autor:
Charles J. Bedord, John M. Young, Lawrence M. de Young, Bonnie M. Wagner, Doreen A. Spires, Stephen J. Ballaron
Publikováno v:
The Journal of investigative dermatology. 82(4)
Application of arachidonic acid (AA) (0.1–4 mg) to the ears of mice produces immediate vasodilatation and erythema (5 min) followed by the abrupt development of edema which is maximal at 40–60 min. The onset of edema coincides with extravasation
Autor:
M. Kruseman, Brad Loe, G. H. Jones, Doreen A. Spires, P. J. Maloney, A. H. Berks, D. V. K. Murthy, R. A. Simpson, M. C. Venuti, John M. Young
Publikováno v:
Journal of medicinal chemistry. 29(8)
On the basis of previous observations that both 2,3-dihydro-2,2,3,3-tetrahydroxy-1,4-naphthoquinone (oxoline, 1) and 6-chloroisonaphthazarin (2) had demonstrated antipsoriatic activity in vivo, a series of structural derivatives of 2 were prepared an
Autor:
Richard J. Simpson, Doreen A. Spires, Murthy D V Krishna, Patrick R. Maloney, John K. Young, Paul S. Cheung, Karen Kappas, S. H. Unger, A. H. Berks, Sussan Rouhafza, Brad Loe, Michael C. Venuti, Colin C. Beard, Myriam Kruseman, Jones Gordon H
Publikováno v:
Journal of Medicinal Chemistry. 29:2534-2534