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Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity

Autor: Powell,David R, Doree,Deon D, DaCosta,Christopher M, Platt,Kenneth A, Hansen,Gwenn M, van Sligtenhorst,Isaac, Ding,Zhi-Ming, Revelli,Jean-Pierre, Brommage,Robert

Publikováno v: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.

David R Powell, Deon D Doree, Christopher M DaCosta, Kenneth A Platt, Gwenn M Hansen, Isaac van Sligtenhorst, Zhi-Ming Ding, Jean-Pierre Revelli, Robert Brommage Lexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USACorrespondence: David R Powell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dovemedicalp::4cb4156bc37e570c882deacee9ddd4f6
https://www.dovepress.com/obesity-of-g2e3-knockout-mice-suggests-that-obesity-associated-variant-peer-reviewed-article-DMSO

Mice Lacking Gpr75 are Hypophagic and Thin.

Autor: Powell, David R, Doree, Deon D, DaCosta, Christopher M, Platt, Kenneth A, Brommage, Robert, Buhring, Lindsey, Revelli, Jean-Pierre, Shadoan, Melanie K

Publikováno v: Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy; Jan2022, Vol. 15, p45-58, 14p

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LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2.

Autor: Powell DR; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Smith MG; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Doree DD; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Harris AL; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Xiong WW; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Mseeh F; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Wilson A; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Gopinathan S; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Diaz D; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Goodwin NC; Lexicon Pharmaceuticals Inc. Princeton, New Jersey., Harrison B; Lexicon Pharmaceuticals Inc. Princeton, New Jersey., Strobel E; Lexicon Pharmaceuticals Inc. Princeton, New Jersey., Rawlins DB; Lexicon Pharmaceuticals Inc. Princeton, New Jersey., Carson K; Lexicon Pharmaceuticals Inc. Princeton, New Jersey., Zambrowicz B; Lexicon Pharmaceuticals Inc. The Woodlands, Texas., Ding ZM; Lexicon Pharmaceuticals Inc. The Woodlands, Texas.

Publikováno v: Pharmacology research & perspectives [Pharmacol Res Perspect] 2015 Mar; Vol. 3 (2), pp. e00129. Date of Electronic Publication: 2015 Mar 31.