Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dorcas A. Annan"'
Autor:
Masahiro Morimoto, Nako Maishi, Takuya Tsumita, Mohammad Towfik Alam, Hiroshi Kikuchi, Yasuhiro Hida, Yusuke Yoshioka, Takahiro Ochiya, Dorcas A. Annan, Ryo Takeda, Yoshimasa Kitagawa, Kyoko Hida
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTumor blood vessels play a key role in tumor metastasis. We have previously reported that tumor endothelial cells (TECs) exhibit abnormalities compared to normal endothelial cells. However, it is unclear how TECs acquire these abnormalities
Externí odkaz:
https://doaj.org/article/3a14a1337c614eb8984fa9e0ac81e8bb
Autor:
Li Cong, Nako Maishi, Dorcas A. Annan, Marian F. Young, Hirofumi Morimoto, Masahiro Morimoto, Jin-Min Nam, Yasuhiro Hida, Kyoko Hida
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background Biglycan is a proteoglycan found in the extracellular matrix. We have previously shown that biglycan is secreted from tumor endothelial cells and induces tumor angiogenesis and metastasis. However, the function of stroma biglycan
Externí odkaz:
https://doaj.org/article/92803b749a824931810385b84c5f291e
Autor:
Dorcas A. Annan, Nako Maishi, Tomoyoshi Soga, Randa Dawood, Cong Li, Hiroshi Kikuchi, Takayuki Hojo, Masahiro Morimoto, Tetsuya Kitamura, Mohammad Towfik Alam, Kazuyuki Minowa, Nobuo Shinohara, Jin-Min Nam, Yasuhiro Hida, Kyoko Hida
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Tumor endothelial cells (TECs) perform tumor angiogenesis, which is essential for tumor growth and metastasis. Tumor cells produce large amounts of lactic acid from glycolysis; however, the mechanism underlying the survival of TEC
Externí odkaz:
https://doaj.org/article/c0dcf36585064ceab340b49e02caf932
Publikováno v:
Cancers, Vol 11, Iss 10, p 1511 (2019)
Tumor blood vessels supply nutrients and oxygen to tumor cells for their growth and provide routes for them to enter circulation. Thus, angiogenesis, the formation of new blood vessels, is essential for tumor progression and metastasis. Tumor endothe
Externí odkaz:
https://doaj.org/article/251da444c4e74865b8310a545c42e7bd
Autor:
Nako Maishi, Hiroshi Kikuchi, Masumi Sato, Hiroko Nagao-Kitamoto, Dorcas A. Annan, Shogo Baba, Takayuki Hojo, Misa Yanagiya, Yusuke Ohba, Genichiro Ishii, Kenkichi Masutomi, Nobuo Shinohara, Yasuhiro Hida, Kyoko Hida
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4595 (2019)
Tumor angiogenesis research and antiangiogenic drug development make use of cultured endothelial cells (ECs) including the human microvascular ECs among others. However, it has been reported that tumor ECs (TECs) are different from normal ECs (NECs).
Externí odkaz:
https://doaj.org/article/62eabf35f462463bbbca2bb831a1882c
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1272 (2018)
Tumor progression depends on the process of angiogenesis, which is the formation of new blood vessels. These newly formed blood vessels supply oxygen and nutrients to the tumor, supporting its progression and providing a gateway for tumor metastasis.
Externí odkaz:
https://doaj.org/article/854d57ba431a4a5cbf18c937ab33a251
Autor:
Masanobu Shindoh, Yasuhiro Hida, Hiroshi Kikuchi, Shinya Tanaka, Misa Yanagiya, Dorcas A. Annan, Aya Yanagawa Matsuda, Nako Maishi, Randa Dawood, Chisaho Torii, Yoshimasa Kitagawa, Tetsuya Kitamura, Yoichi Ohiro, Kyoko Hida
Publikováno v:
Pathology International. 71:383-391
Oral squamous cell carcinoma (OSCC) impairs functionality and sensuousness resulting in poor quality of life. Biomarkers can predict disease trajectory and lead to effective treatments. Transcriptomics have identified genes that are upregulated in tu
Autor:
Mohammad Towfik Alam, Hiroshi Kikuchi, Cong Li, Randa Dawood, Takayuki Hojo, Nako Maishi, Tomoyoshi Soga, Kyoko Hida, Jin Min Nam, Nobuo Shinohara, Dorcas A. Annan, Kazuyuki Minowa, Yasuhiro Hida, Tetsuya Kitamura, Masahiro Morimoto
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
BackgroundTumor endothelial cells (TECs) perform tumor angiogenesis, which is essential for tumor growth and metastasis. Tumor cells produce large amounts of lactic acid from glycolysis; however, the mechanism underlying the survival of TECs to enabl
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3238, p 3238 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3238, p 3238 (2020)
Going from bench to bedside is a simplified description of translational research, with the ultimate goal being to improve the health status of mankind. Tumor endothelial cells (TECs) perform angiogenesis to support the growth, establishment, and dis
Autor:
Takahiro Osawa, Nako Maishi, Naoto Miyajima, Kyoko Hida, Kaname Ameda, Yoshihiro Matsuno, Masumi Sato, Ryo Takeda, Akira Kashiwagi, Hiroshi Kikuchi, Dorcas A. Annan, Mohammad Towfik Alam, Keita Ishizuka, Randa Dawood, Masahiro Morimoto, Katsushige Yamashiro, Nobuo Shinohara, Satoru Maruyama, Ryuji Matsumoto, Manabu Azuma, Kunihiko Tsuchiya, Tomoshige Akino, Yasuhiro Hida, Takashige Abe, Toru Harabayashi
Publikováno v:
Cancer research. 80(14)
Tumor endothelial cells (TEC) lining tumor blood vessels actively contribute to tumor progression and metastasis. In addition to tumor cells, TEC may develop drug resistance during cancer treatment, allowing the tumor cells to survive chemotherapy an